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  3. Plagerine 75 mg Tablet 15's

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

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Whats That

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Composition :

CLOPIDOGREL-75MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Plagerine Tablet

Plagerine Tablet consists of the anti-platelet drug (blood thinner) primarily taken for the prevention of heart attack or stroke in people at high risk of heart disease. A heart attack generally refers to the blocked flow of blood to the heart because of the blockage of arteries. A heart blockage is most often a build-up of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Plagerine Tablet belongs to a class of medications called a blood thinner or an antiplatelet medication. Plagerine Tablet plays a vital role in preventing the formation of harmful blood clots (plaque) in your veins. It makes your blood flow easy through your veins making it less likely to form a serious blood clot. So, an intake of Plagerine Tablet helps prevent blood clots if you have an increased risk of having severe chest pain (unstable angina or heart attack), stroke, peripheral arterial disease (heart problem due to narrowed blood vessels).

The recommended daily dose of Plagerine Tablet is 75 mg once daily orally, with or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience nosebleeds, heavier periods, bleeding gums, easy bruising, diarrhoea, stomach pain, indigestion, or heartburn. If the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping a sudden intake of Plagerine Tablet may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Let your doctor know if you have any liver, kidney, or heart problems. Plagerine Tablet should be taken cautiously in pregnant or breastfeeding women. It should be not given to people with a bleeding disorder (haemophilia), active pathological bleeding, like a peptic ulcer, or bleeding in the brain (intracranial haemorrhage). Do not take Plagerine Tablet with aspirin or ibuprofen for pain relief while you are using Plagerine Tablet . It may increase the chance of having stomach ulcers or severe gastric bleeding.

Uses of Plagerine Tablet

Prevention of heart attack, Prevention of stroke, Prevention of heart related chest pain (angina)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Plagerine Tablet plays a vital role to prevent the formation of harmful blood clots in your blood vessels by making platelets (clotting agents) sticking together. Thus, it helps to reduce the risk of heart attack, stroke, unstable angina (heart related chest pain), peripheral arterial disease (blocked or poor blood flow due to narrowed blood vessels) in heart disease patients and patient who have undergone recent heart surgery with stent.

Storage

Keep Plagerine Tablet out of the sight and reach of children.

Drug Warnings

Indigestion medicines known as proton pump inhibitors like omeprazole should be used with caution while taking Plagerine Tablet . Prolonged use of Plagerine Tablet can cause bleeding problems (like nosebleeds, heavier periods, bleeding gums, and easy bruising). If you are going to have any surgery, discontinue taking Plagerine Tablet 5 days before the surgery. Discontinuation of Plagerine Tablet might increase the risk of heart attack, stroke, and other risks of cardiovascular events. So, do not stop taking Plagerine Tablet of a sudden on your own decision. If you have had any recent stroke or heart attack, stop the intake of Plagerine Tablet with painkillers like aspirin or ibuprofen as it can increase your stomach or gastrointestinal bleeding. Purpura (blood leakage under the skin) has been observed with the use of Plagerine Tablet including in fatal cases.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Plagerine 75 mg Tablet:
When Selexipag and Plagerine 75 mg Tablet are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Plagerine 75 mg Tablet with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Taking Plagerine 75 mg Tablet together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Plagerine 75 mg Tablet with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Taking Plagerine 75 mg Tablet together with argatroban can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Plagerine 75 mg Tablet and Apixaban, they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding, like feeling dizzy or lightheaded, red or black, sticky stools, or severe headaches. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Taking Plagerine 75 mg Tablet and Dasatinib together can increase the risk of bleeding.

How to manage the interaction:
Taking Plagerine 75 mg Tablet together with Dasatinib may result in an interaction, but they can be taken if prescribed by a doctor. However, if you experience dizzy or lightheaded, red or black, sticky stools, or a severe headache, consult a doctor without any delay. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Co-administration of Cangrelor with Plagerine 75 mg Tablet and reduce its effectiveness if used at the same time.

How to manage the interaction:
Although taking Plagerine 75 mg Tablet with cangrelor can result in an interaction, they can be taken together if prescribed by a doctor. Plagerine 75 mg Tablet should be taken after the Cangrelor infusion is complete. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Coadministration of Plagerine 75 mg Tablet with Esomeprazole may reduce the effectiveness of Plagerine 75 mg Tablet.

How to manage the interaction:
Taking Plagerine 75 mg Tablet and esomeprazole together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
ClopidogrelTipranavir
Severe
How does the drug interact with Plagerine 75 mg Tablet:
Taking Tipranavir with Plagerine 75 mg Tablet can make the blood-thinning effects of Plagerine 75 mg Tablet stronger.

How to manage the interaction:
Although there is a possible interaction between Plagerine 75 mg Tablet and Tipranavir, you can take these medicines together if prescribed by your doctor. If you notice any bleeding, severe headaches, weakness, or black stools, contact your doctor right away. Do not stop using any medications without talking to your doctor.
ClopidogrelProtamine
Severe
How does the drug interact with Plagerine 75 mg Tablet:
Taking Protamine with Plagerine 75 mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Taking Protamine with Plagerine 75 mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Taking loperamide with Plagerine 75 mg Tablet may significantly increase the blood levels of loperamide. This can lead to serious and complications such as irregular heart rhythm.

How to manage the interaction:
Although talking Plagerine 75 mg Tablet with loperamide may result in an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Taking Plagerine 75 mg Tablet with acalabrutinib may increase the risk of bleeding.

How to manage the interaction:
There could be a possible interaction between Plagerine 75 mg Tablet and Acalabrutinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding, like feeling dizzy or lightheaded, red or black, sticky stools, or severe headaches. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A low cholesterol diet and a regular exercise regime complement treatment with Plagerine Tablet effectively.
  • Stick to a freshly prepared home-cooked meal and avoid processed, packed foods that contain hidden sugar and extra calories.
  • Try to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL cholesterol (bad cholesterol) in a short period.
  • Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
  • Quit smoking and avoid excessive intake of alcohol.

Side Effects of Plagerine Tablet

  • Nosebleeds
  • Heavier periods
  • Bleeding gums
  • Easy bruising
  • Diarrhoea
  • Stomach pain
  • Indigestion or heartburn

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • RIVAROXABAN
  • APIXABAN
  • IBUPROFEN
  • CITALOPRAM
  • OMEPRAZOLE

Special Advise

  • As Plagerine Tablet tends to increase bleeding, try to avoid injuries, keep away from sharp objects, and inform your doctor if you have peptic ulcers or injuries.

Disease/Condition Glossary

A blood clot can occur in any part of the body that can lead to a heart attack, stroke, and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. On the other hand, deep vein thrombosis (blood clot in veins), peripheral artery disease (narrowed arteries due to fat deposit or blood clot), and atherosclerosis (fat build upon the walls of the arteries) can cause a blood clot in your limbs.

Have a query?

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Alcohol

Caution

You can drink alcohol with Plagerine Tablet . But do not drink too much while taking this medicine. It can irritate your stomach.

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Pregnancy

Caution

Plagerine Tablet should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Caution

Plagerine Tablet should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Safe if prescribed

Plagerine Tablet has no or negligible influence on the ability to drive or use machines.

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Liver

Safe if prescribed

No dosage adjustment is necessary in patients with liver disease.

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Kidney

Caution

Plagerine Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Plagerine Tablet is not recommended for children. The safety and effectiveness of Plagerine Tablet have not been established in children due to limited testing of this drug on children by competent authorities across the world.

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