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Reviewed By Sunny S , MBBS

About Polytorva 2.5 mg Capsule Kit 1's

Polytorva 2.5 mg Capsule Kit 1's is a combination drug of blood thinners, cholesterol-lowering agents and blood pressure-lowering agents primarily used to prevent heart attack and stroke. Besides this, it also lowers the raised level of bad cholesterol (especially for those at high risk of heart disease). A heart attack generally refers to a blocked flow of blood to the heart due to the blockage of arteries. The blockage is most often a build-up of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Polytorva 2.5 mg Capsule Kit 1's is composed of three medicines: Atorvastatin, Ramipril, and Aspirin. Atorvastatin is a cholesterol-lowering medication that blocks the enzyme required to make fat in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). Aspirin is blood thinners or antiplatelet (anticoagulant) that collectively prevent clots in the blood vessels. Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II that tightens your blood vessels, thereby relaxing blood vessels in the body and reducing overload on the heart to pump more blood. Together Polytorva 2.5 mg Capsule Kit 1'sminimisess the risk of heart attack, stroke, and heart-related chest pain (angina).

Depending upon your medical condition, you are advised to take Polytorva 2.5 mg Capsule Kit 1's for as long as your doctor has prescribed it for you. The most common side effects of Polytorva 2.5 mg Capsule Kit 1's are increased bleeding tendency, constipation, headache, muscle pain, weakness, headaches, decreased blood pressure, dizziness, muscle pain, increased blood glucose level, and cough in some cases. Most of these side effects of Polytorva 2.5 mg Capsule Kit 1's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping Polytorva 2.5 mg Capsule Kit 1's abruptly may worsen your condition and increase your risk of a future heart attack. Let your doctor know if you are sensitive to atorvastatin, or aspirin, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), muscle problems (myopathy, rhabdomyolysis), are pregnant or planning to become pregnant or breastfeeding. Atorvastatin, present in Polytorva 2.5 mg Capsule Kit 1's, is a pregnancy category X drug, so it is contraindicated in pregnant women. As it may cause harm to the fetus if administered to pregnant women. Disclose to your doctor that you are taking Polytorva 2.5 mg Capsule Kit 1's if you are going to have any surgery.

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Non returnable*
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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

Uses of Polytorva 2.5 mg Capsule Kit 1's

Prevention of heart attack, Prevention of stroke, Angina (heart-related chest pain)

Medicinal Benefits

Polytorva 2.5 mg Capsule Kit 1's is a combination drug of a blood-thinning agent (aspirin), cholesterol-lowering agent (atorvastatin) and blood pressure-lowering agent (ramipril) primarily taken to prevent heart attack and stroke in people with heart problems. It also lowers the raised level of bad cholesterol (especially for those at high risk of heart disease). Additionally, it is also given to patients who had a recent heart bypass surgery to control cholesterol levels and prevent blood clots. Polytorva 2.5 mg Capsule Kit 1's is composed of three medicines: Atorvastatin, Ramipril, and Aspirin. Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). Aspirin is blood thinners or antiplatelet (anticoagulant) that collectively prevent clots in the blood vessels. Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lower increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and helps lower high blood pressure. Together Polytorva 2.5 mg Capsule Kit 1's reduces the risk of heart attack, stroke, and heart-related chest pain (angina).

Side Effects of Polytorva 2.5 mg Capsule Kit 1's

  • Bleeding tendency
  • Constipation
  • Headache
  • Muscle pain
  • Weakness
  • Headaches
  • Decreased blood pressure
  • Dizziness
  • Muscle pain
  • An increased blood glucose level
  • Cough in some cases

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you are highly sensitive to atorvastatin, ramipril or aspirin, have any active liver disease, have active bleeding issues (like a peptic ulcer or brain haemorrhage), are pregnant or planning to become pregnant, or breastfeeding. The patient should inform the doctor they are taking Polytorva 2.5 mg Capsule Kit 1's before any surgery or any new medicine is taken. Atorvastatin, present in Polytorva 2.5 mg Capsule Kit 1's, is a pregnancy category X drug, so it is contraindicated in pregnant women. As it may cause harm to the fetus if administered to a pregnant woman. Co-administration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know about this. Polytorva 2.5 mg Capsule Kit 1's contains atorvastatin which can cause muscle problems like myopathy and rhabdomyolysis. So, any signs of muscle pain, tenderness, or weakness, during the initial months of the treatment should be closely monitored. Patients with active liver disease should use Polytorva 2.5 mg Capsule Kit 1's with caution. The safety and effectiveness of Polytorva 2.5 mg Capsule Kit 1's have not been established, so its use should be avoided in pediatric patients or children less than 12 years of age. Discontinuation of Polytorva 2.5 mg Capsule Kit 1's may lead to cardiovascular events like heart attack, stroke, and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Polytorva 2.5 mg Capsule Kit 1's.

Therapeutic Class

CARDIOVASCULAR AGENTS

Drug-Drug Interactions

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RamiprilAliskiren
Critical
AspirinKetorolac
Critical

Drug-Drug Interactions

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RamiprilAliskiren
Critical
How does the drug interact with Polytorva 2.5 mg Capsule Kit 1's:
Taking aliskiren together with Polytorva 2.5 mg Capsule Kit 1's may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Polytorva 2.5 mg Capsule Kit 1's with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
AspirinKetorolac
Critical
How does the drug interact with Polytorva 2.5 mg Capsule Kit 1's:
Co-administration of Ketorolac and Polytorva 2.5 mg Capsule Kit 1's may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Polytorva 2.5 mg Capsule Kit 1's is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
AspirinKetorolac tromethamine
Critical
How does the drug interact with Polytorva 2.5 mg Capsule Kit 1's:
Combining Ketorolac tromethamine with Polytorva 2.5 mg Capsule Kit 1's can increase the risk of adverse effects.

How to manage the interaction:
Taking Polytorva 2.5 mg Capsule Kit 1's with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
AtorvastatinPosaconazole
Critical
How does the drug interact with Polytorva 2.5 mg Capsule Kit 1's:
Taking Polytorva 2.5 mg Capsule Kit 1's with Posaconazole can increase the blood levels of Polytorva 2.5 mg Capsule Kit 1's. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Polytorva 2.5 mg Capsule Kit 1's, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
RamiprilPotassium citrate
Severe
How does the drug interact with Polytorva 2.5 mg Capsule Kit 1's:
Taking Potassium citrate with Polytorva 2.5 mg Capsule Kit 1's may increase potassium levels in the blood. High potassium levels can lead to kidney problems, muscle paralysis, and abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Polytorva 2.5 mg Capsule Kit 1's, you can take these medicines together if prescribed by your doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
RamiprilTizanidine
Severe
How does the drug interact with Polytorva 2.5 mg Capsule Kit 1's:
Taking Polytorva 2.5 mg Capsule Kit 1's with Tizanidine may have additive effects in lowering your blood pressure

How to manage the interaction:
Although taking Polytorva 2.5 mg Capsule Kit 1's together with Tizanidine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you feel headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate. If you have the above symptoms, avoid tasks requiring attentiveness, such as driving or using dangerous machinery. Be careful when you stand up from a sitting or lying position. Do not stop taking any medication without consulting your doctor.
RamiprilLeflunomide
Severe
How does the drug interact with Polytorva 2.5 mg Capsule Kit 1's:
Taking leflunomide with Polytorva 2.5 mg Capsule Kit 1's can increase the risk of liver problems.

How to manage the interaction:
Although taking Polytorva 2.5 mg Capsule Kit 1's with Leflunomide can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RamiprilAzilsartan medoxomil
Severe
How does the drug interact with Polytorva 2.5 mg Capsule Kit 1's:
Taking Azilsartan medoxomil with Polytorva 2.5 mg Capsule Kit 1's may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Polytorva 2.5 mg Capsule Kit 1's together with Azilsartan medoxomil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, confusion, tingling in the hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.
RamiprilOlmesartan medoxomil
Severe
How does the drug interact with Polytorva 2.5 mg Capsule Kit 1's:
Taking Polytorva 2.5 mg Capsule Kit 1's together with olmesartan may increase the risk of side effects (blood pressure, kidney function impairment, and a condition called Hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking olmesartan medoxomil with Polytorva 2.5 mg Capsule Kit 1's may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
RamiprilValsartan
Severe
How does the drug interact with Polytorva 2.5 mg Capsule Kit 1's:
Taking Polytorva 2.5 mg Capsule Kit 1's with Valsartan may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Polytorva 2.5 mg Capsule Kit 1's together with Valsartan can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. Do not stop taking any medication without consulting a doctor.

Drug-Food Interactions

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ATORVASTATIN-10MG+RAMIPRIL-2.5MG+ASPIRIN-75MGPotassium rich foods, Grapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ATORVASTATIN-10MG+RAMIPRIL-2.5MG+ASPIRIN-75MGPotassium rich foods, Grapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Grapefruit, Grapefruit Juice

How to manage the interaction:
Taking potassium rich food, grapefruit and grape juice while on the treatment withRamipril, Atorvastatin and Aspirin can increase the levels of potassium salt in blood and other side effects like nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, confusion, or slow or rapid heartbeat. Limit or avoid caking potassium rich food, grapefruit and grape juice while on the treatment with Ramipril, Atorvastatin and Aspirin.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • RITONAVIR
  • LOPINAVIR
  • DARUNAVIR
  • ATAZANAVIR
  • INDINAVIR
  • ITRACONAZOLE
  • WARFARIN
  • HEPARIN
  • COLCHICINE
  • DIGOXIN
  • CYCLOSPORINE

Diet & Lifestyle Advise

  • Eat a healthy diet rich in soluble fibre like beans, legumes, whole grains, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol quickly. Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, low in red meat and most dairy.
  • Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants that help to lower LDL - low-density lipoprotein (bad cholesterol)
  • Minimize the intake of added sugar. The American Heart Association (ADA) recommends one should not eat more than 100 calories (25 grams) of added sugar for women and children and no more than 150 calories (37.5 grams) for men every day.
  • American Heart Association recommends sodium chloride intake (table salt) should not exceed more than 2,300 mg per day as part of a healthy eating pattern.
  • As a precautionary measure, do not consume alcohol and quit smoking.

Habit Forming

No

Special Advise

  • Please monitor your blood sugar (H1b1AC) level regularly.

Disease/Condition Glossary

Heart attack: A heart attack generally refers to a blocked flow of blood to the heart due to the blockage of arteries. The blockage is most often a build-up of fat, cholesterol, and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Stroke: Stroke occurs when the blood and oxygen supply to the brain is limited or stopped. When the brain does not receive sufficient oxygen and nutrients, it starts dying within a few minutes. If not treated early, it is a life-threatening condition that can lead to brain damage, coma, and even death.

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