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Manufacturer/Marketer :

Boehringer Ingelheim India Pvt Ltd

Consume Type :

ORAL

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About Pradaxa 110 mg Capsule

Pradaxa 110 mg Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), and to reduce the risk of clots in people who have undergone knee or hip replacement surgeries. 

Pradaxa 110 mg Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Pradaxa 110 mg Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Take Pradaxa 110 mg Capsule as prescribed by your doctor. You are advised to take Pradaxa 110 mg Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects of Pradaxa 110 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Pradaxa 110 mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Pradaxa 110 mg Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Pradaxa 110 mg Capsule . Try not to stop taking this medicine on your own. Discontinuing Pradaxa 110 mg Capsule may worsen your condition and increase the risk of heart attack, and stroke.

Uses of Pradaxa 110 mg Capsule

Prevention of blood clot formation, deep vein thrombosis, pulmonary embolism.

Directions for Use

Take Pradaxa 110 mg Capsule exactly as your doctor has prescribed it. Swallow it as a whole with water; do not crush or chew it.

Medicinal Benefits

Pradaxa 110 mg Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Pradaxa 110 mg Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Pradaxa 110 mg Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pradaxa 110 mg Capsule

  • Stomach pain
  • Vomiting
  • Bleeding
  • Anaemia (low number of red blood cells)
  • Nausea
  • Diarrhoea

Drug Warnings

If you are known to be allergic to Pradaxa 110 mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Pradaxa 110 mg Capsule . Pradaxa 110 mg Capsule is not recommended for children less than 18 years of age as the Safety and effectiveness have not been established. If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Pradaxa 110 mg Capsule . You should inform the doctor that you are taking Pradaxa 110 mg Capsule if you are due to undergo surgery. Avoid consumption of alcohol while taking Pradaxa 110 mg Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilateKetoconazole
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Pradaxa 110 mg Capsule:
When Mifepristone is taken with Pradaxa 110 mg Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Pradaxa 110 mg Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateKetoconazole
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Coadministration of Ketoconazole and Pradaxa 110 mg Capsule may increase the blood levels and effects Pradaxa 110 mg Capsule. This may increase the risk of anemia and bleeding issues.

How to manage the interaction:
Although taking Ketoconazole and Pradaxa 110 mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you notice paleness, exhaustion, dizziness, fainting, unusual bleeding or bruising, swelling, nausea, vomiting, blood in your urine or stools, headache, or weakness, consult a doctor. Do not discontinue any medication without consulting a doctor.
Dabigatran etexilateFosphenytoin
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
When Pradaxa 110 mg Capsule is taken with Fosphenytoin, it can lower the rate at which the body breaks down Pradaxa 110 mg Capsule. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Fosphenytoin with Pradaxa 110 mg Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms like sudden breathlessness, sharp chest pain, throbbing, cramping pain, swelling, redness or warmth in legs or arms, it's important to let your doctor know right away. They can recommend other options that won't cause any problems with your current medications. Do not discontinue any medications without first consulting your doctor.
Dabigatran etexilateLepirudin
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Taking Pradaxa 110 mg Capsule with Lepirudin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 110 mg Capsule with Lepirudin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateDefibrotide
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Taking Pradaxa 110 mg Capsule with Defibrotide can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 110 mg Capsule with Defibrotide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilatePiroxicam
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Coadministration of Piroxicam with Pradaxa 110 mg Capsule can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Piroxicam and Pradaxa 110 mg Capsule, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
Dabigatran etexilatePhenobarbital
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Phenobarbital can drastically lower Pradaxa 110 mg Capsule blood levels, making the medicine less effective in treating and preventing blood clots.

How to manage the interaction:
Although taking phenobarbital with Pradaxa 110 mg Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateMeloxicam
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Co-administration of Meloxicam with Pradaxa 110 mg Capsule together can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Pradaxa 110 mg Capsule and Meloxicam, you can take these medicines together if prescribed by a doctor. If you notice any of these symptoms - bleeding, bruising, feeling dizzy or weak, black or tarry stools, severe headaches, or bleeding or vomiting - contact a doctor right away. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateAlteplase
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Taking Pradaxa 110 mg Capsule with Alteplase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 110 mg Capsule with Alteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateApixaban
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Coadministration of Pradaxa 110 mg Capsule and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Pradaxa 110 mg Capsule and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Pradaxa 110 mg Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Pradaxa 110 mg Capsule treatment.

Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Pradaxa 110 mg Capsule Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Pradaxa 110 mg Capsule is a thrombin inhibitor. The inhibition of thrombin, reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.

No, you are not recommended to stop taking Pradaxa 110 mg Capsule without consulting your doctor as it may worsen the condition. Therefore, take Pradaxa 110 mg Capsule for as long as your doctor has prescribed it.

Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Pradaxa 110 mg Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Taking Pradaxa 110 mg Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Pradaxa 110 mg Capsule .

Pradaxa 110 mg Capsule may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.

Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENPROCOUMON
  • ACENOCOUMAROL
  • HEPARIN
  • CLOPIDOGREL
  • PRASUGREL
  • TICAGRELOR
  • RIVAROXABAN
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • VERAPAMIL
  • ITRACONAZOLE
  • KETOCONAZOLE
  • TACROLIMUS
  • CYCLOSPORINE
  • INDINAVIR
  • RITONAVIR
  • RIFAMPICIN
  • CLARITHROMYCIN
  • GLECAPREVIR
  • PIBRENTASVIR
  • IBUPROFEN
  • DICLOFENAC
  • PHENYTOIN
  • CARBAMAZEPINE

Special Advise

  • You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalized ratio) to analyze your blood clotting time.
  • In case you miss a dose of Pradaxa 110 mg Capsule , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.

Disease/Condition Glossary

Thrombosis/Blood Clot: A blood clot can occur in any part of the body and can lead to a heart attack, stroke, or damage to organs. Blood clots can reach the arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. 

Deep vein thrombosis (blood clots in legs): It is a medical condition in which blood clots form in deep veins, usually in the legs. The symptoms include leg pain or swelling. 

Pulmonary embolism (blood clots in the lung): It is a chronic condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain, and shortness of breath.

Stroke (blood clots in the brain): It occurs when the supply of blood to part of your brain is stopped or reduced. This prevents brain tissue from getting nutrients and oxygen leading to the death of brain cells.

Heart attack: A heart attack means the death of heart tissue due to a shortage of blood supply to the heart muscles. This can occur when there is an accumulation of cholesterol or fat narrowing the heart's major veins or when other substances like a blood clot are blocking the flow of blood. 

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