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  3. Prazoqol DSR Capsule 10's

Prazoqol DSR Capsule 10's, Pack of 10 CapsuleS
Prazoqol DSR Capsule 10's, Pack of 10 CapsuleS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Hari Kumar , MBBS
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Whats That

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Composition :

DOMPERIDONE-30MG + PANTOPRAZOLE-40MG

Manufacturer/Marketer :

Proqol Health Care Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Prazoqol DSR Capsule

Prazoqol DSR Capsule is composed of two medicines, namely: Domperidone and Pantoprazole. Domperidone is a prokinetic and anti-nausea agent that helps to treat indigestion and stomach pain. On the other hand, Pantoprazole is a proton pump inhibitor that reduces the excess stomach acid formation by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). Prazoqol DSR Capsule is a widely used medicine to treat peptic ulcers and gastroesophageal reflux disease (GERD). Prazoqol DSR Capsule prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and in this way reduces the feeling of bloating, or fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, that is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum.

It should be taken as prescribed by the doctor. Like all medicines, Prazoqol DSR Capsule may cause side effects, although not everybody gets them. The most common side effects of Prazoqol DSR Capsule are diarrhoea, stomach pain, flatulence (gas), dryness in the mouth, dizziness, and headache. Everyone doesn't need to experience the above side effects. In case of any discomfort, speak with your doctor.

It is recommended not to use if you are allergic to any ingredinets present in it. Prolonged intake of Pantoprazole is associated with a low level of Vitamin B12 and low magnesium. Hence yearly test of Vitamin B12 and magnesium is required if you are taking Prazoqol DSR Capsule for the long term. Use of Prazoqol DSR Capsule is contraindicated in people with lupus (autoimmune inflammatory disease). Try to avoid caffeine-containing beverages (coffee, tea), spicy/deep fried/processed foods, carbonated drinks, acidic foods like citrus fruits/vegetables (tomatoes).

Uses of Prazoqol DSR Capsule

Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of food pipe (esophagitis), Peptic ulcer.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Prazoqol DSR Capsule plays a vital role in preventing nausea, vomiting, stomach upset, stomach pain, peptic ulcer, and other conditions due to hyperacidity or acid reflux. Pantoprazole prevents the proton pumps gate from producing an excessive amount of stomach acid. While Domperidone stops nausea (feeling sick) and vomiting (being sick) blocking messages between parts of your brain called the chemoreceptor trigger zone (CTZ) and the vomiting centre.

Storage

Keep Prazoqol DSR Capsule out of the sight and reach of children.

Drug Warnings

You should avoid taking Prazoqol DSR Capsule if you are allergic to Prazoqol DSR Capsule or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Prazoqol DSR Capsule may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Prazoqol DSR Capsule may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Prazoqol DSR Capsule may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor.

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
PantoprazoleDacomitinib
Severe

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with Prazoqol DSR Capsule:
Co-administration of Rilpivirine is taken with Prazoqol DSR Capsule, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking Prazoqol DSR Capsule with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PantoprazoleDacomitinib
Severe
How does the drug interact with Prazoqol DSR Capsule:
Taking Prazoqol DSR Capsule can make Dacomitinib less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Prazoqol DSR Capsule with Dacomitinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleAtazanavir
Severe
How does the drug interact with Prazoqol DSR Capsule:
Co-administration of Prazoqol DSR Capsule reduces stomach acid, decreases the absorption and blood levels of Atazanavir, and reduces its effectiveness.

How to manage the interaction:
Taking Prazoqol DSR Capsule with Atazanavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleErlotinib
Severe
How does the drug interact with Prazoqol DSR Capsule:
Taking Erlotinib with Prazoqol DSR Capsule may interfere with the absorption of Erlotinib into the bloodstream, and reduce its effectiveness.

How to manage the interaction:
Taking Prazoqol DSR Capsule with Erlotinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleMethotrexate
Severe
How does the drug interact with Prazoqol DSR Capsule:
Co-administration of Methotrexate with Prazoqol DSR Capsule can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Prazoqol DSR Capsule and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
PantoprazoleDasatinib
Severe
How does the drug interact with Prazoqol DSR Capsule:
Taking Dasatinib with Prazoqol DSR Capsule may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Prazoqol DSR Capsule with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
PantoprazoleGefitinib
Severe
How does the drug interact with Prazoqol DSR Capsule:
Taking Gefitinib with Prazoqol DSR Capsule reduces the acidity level in the stomach and may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Taking Prazoqol DSR Capsule with Gefitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take gefitinib 12 hours before or 12 hours after Prazoqol DSR Capsule to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.
PantoprazolePazopanib
Severe
How does the drug interact with Prazoqol DSR Capsule:
Taking Prazoqol DSR Capsule with Pazopanib may reduce the effectiveness of pazopanib.

How to manage the interaction:
If you are supposed to take Prazoqol DSR Capsule and Pazopanib together, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PantoprazoleNelfinavir
Severe
How does the drug interact with Prazoqol DSR Capsule:
Taking Nelfinavir with Prazoqol DSR Capsule may decrease the absorption and blood levels of Nelfinavir and reduce its effectiveness.

How to manage the interaction:
Taking Prazoqol DSR Capsule with Nelfinavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
DomperidoneMethadone
Severe
How does the drug interact with Prazoqol DSR Capsule:
Coadministration of Prazoqol DSR Capsule with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Prazoqol DSR Capsule and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre-containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B 12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Take a break of 5 minutes in 1 hour by brisk walking or stretching.

Side Effects of Prazoqol DSR Capsule

  • Headache
  • Diarrhoea
  • Nausea
  • Abdominal pain
  • Vomiting
  • Flatulence
  • Dizziness
  • Arthralgia (joint pain)

Habit Forming

No

Therapeutic Class

ANTACIDS

Prazoqol DSR Capsule Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and in this way reduces the feeling of bloating, or fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, which is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum.

Prazoqol DSR Capsule can be safely taken as long as your doctor has prescribed it to you.

Yes, taking Prazoqol DSR Capsule for a very long time can cause calcium depletion from the body leading to weakening of bones. Hence a calcium and vitamin D supplement is recommended along with Prazoqol DSR Capsule to replenish calcium depletion in the body.

Yes. Prazoqol DSR Capsule can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.

Prolonged intake of Prazoqol DSR Capsule may weaken your bone and lower haemoglobin level. Your doctor may prescribe you Vitamin B12 for enhancing haemoglobin and calcium/vitamin D/magnesium supplements for bone health.

Combination of pantoprazole and domperidone is effective & safe.

No, Prazoqol DSR Capsule is a prescribed drug with minimal side effects. Only take it if your doctor has recommended it to you for acidity.

Drug-Drug Interactions Checker List

  • CLOPIDOGREL
  • WARFARIN
  • KETOCONAZOLE
  • VORICONAZOLE
  • ITRACONAZOLE
  • POSACONAZOLE
  • ATAZANAVIR
  • NELFINAVIR
  • AMPICILLIN
  • RIFAMPICIN
  • DIGOXIN
  • METHOTREXATE

Disease/Condition Glossary

Normally a thick layer of mucous protects the stomach against its own acid secretion. But, in long run, it gets eroded by excessive stomach acid production leading to complications like GERD, peptic ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a gastrointestinal disorder that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe that causes heartburn. On the other hand, a peptic ulcer is a painful condition followed by the development of sores or ulcers in the stomach lining or duodenum (first part of the small intestine). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

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