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Not for online sale
Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pregeb D 75/30 Capsule

Pregeb D 75/30 Capsule belongs to an anticonvulsant class of medicines. It is used in the treatment of diabetic neuropathic pain and fibromyalgia. Neuropathic pain/ peripheral neuropathy is pain that occurs when the nervous system is not working properly or is damaged. Diabetic neuropathic pain/diabetic neuropathy is a condition causing moderate to severe pain due to damage of nerves in the thigh, hip, buttock and leg regions. Symptoms may include tingling, shooting pain, burning, or even an electric shock sensation. Fibromyalgia is a chronic condition with moderate pain and tenderness all over the body resulting in fatigue and trouble sleeping.

Pregeb D 75/30 Capsule is a combination of Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain.

Pregeb D 75/30 Capsule can be taken with or without food or as prescribed by your doctor. Pregeb D 75/30 Capsule may cause certain side effects such as nausea, constipation, headache, dry mouth, increased sweating, loss of appetite, dizziness, and burning sensation. These side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist, inform your doctor.

Pregeb D 75/30 Capsule should be avoided if you are allergic to it. Inform your doctor if you have any liver or kidney disease, seizures (fits), mania, bipolar disorder, glaucoma (an eye condition), bleeding disorders, or are at risk of hyponatremia (low sodium levels, especially in patients taking diuretics or water pills). If you are pregnant or breastfeeding, inform your doctor before taking this medicine. It is not recommended for use in children and young adults as it increases the risk of suicidal tendencies. 

Uses of Pregeb D 75/30 Capsule

Diabetic Neuropathic Pain, Fibromyalgia

Directions for Use

Take Pregeb D 75/30 Capsule as prescribed by your doctor. Swallow it as a whole with water. It can be taken with or without food. Do not crush, break or chew it.

Medicinal Benefits

Pregeb D 75/30 Capsule contains Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain. Pregeb D 75/30 Capsule effectively treats neuropathic pain, and improves nerve conduction for proper nerve signal functioning in the body. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Pregeb D 75/30 Capsule should be avoided if you are allergic to any of the components in it. Do not stop taking Pregeb D 75/30 Capsule suddenly without your doctor’s advice, as it may cause withdrawal symptoms like dizziness, tingling sensation, sleep disturbances, restlessness, nausea or vomiting, headache, or excessive sweating. Inform your doctor if you have any liver or kidney disease, seizures (fits), mania, bipolar disorder, or glaucoma (an eye condition). Pregeb D 75/30 Capsule may increase suicidal thoughts, so it is advised to use caution in patients with mania, bipolar disorder or depression. It is not recommended for use in children below 18 years of age as the safety and efficacy of this medicine are not established. Pregnant or breastfeeding mothers should inform the doctor before using Pregeb D 75/30 Capsule .

Drug-Drug Interactions

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PregabalinEsketamine
Severe

Drug-Drug Interactions

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PregabalinEsketamine
Severe
How does the drug interact with Pregeb D 75/30 Capsule:
When Pregeb D 75/30 Capsule and Esketamine are taken together, it may increase the risk of side effects.

How to manage the interaction:
Although taking Pregeb D 75/30 Capsule and Esketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregeb D 75/30 Capsule:
Using Pregeb D 75/30 Capsule together with Pentazocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pentazocine and Pregeb D 75/30 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSodium oxybate
Severe
How does the drug interact with Pregeb D 75/30 Capsule:
Using Sodium oxybate together with Pregeb D 75/30 Capsule may increase the risk of side effects.

How to manage the interaction:
Although taking Pregeb D 75/30 Capsule with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. For at least six hours after taking sodium oxybate, avoid operating machinery or engaging in potentially dangerous activities. Also, be careful when getting up from a sitting or lying down posture. Do not stop using any medications without talking to a doctor.
PregabalinAlfentanil
Severe
How does the drug interact with Pregeb D 75/30 Capsule:
Using Pregeb D 75/30 Capsule together with Alfentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Pregeb D 75/30 Capsule and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinSufentanil
Severe
How does the drug interact with Pregeb D 75/30 Capsule:
Using Pregeb D 75/30 Capsule together with Sufentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking sufentanil and Pregeb D 75/30 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinCodeine
Severe
How does the drug interact with Pregeb D 75/30 Capsule:
Using Pregeb D 75/30 Capsule together with Codeine may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Codeine and Pregeb D 75/30 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregeb D 75/30 Capsule:
Using Pregeb D 75/30 Capsule together with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Although taking fentanyl together with Pregeb D 75/30 Capsule can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Pregeb D 75/30 Capsule:
When Tramadol is used with Pregeb D 75/30 Capsule, it may possibly lead to side effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Although taking tramadol and Pregeb D 75/30 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregeb D 75/30 Capsule:
Using Pregeb D 75/30 Capsule together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Pregeb D 75/30 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinHydrocodone
Severe
How does the drug interact with Pregeb D 75/30 Capsule:
Using Pregeb D 75/30 Capsule together with Hydrocodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Pregeb D 75/30 Capsule together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercise regularly, which helps in reducing pain.
  • Rest well, and get enough sleep.
  • Always take a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Pregeb D 75/30 Capsule contains Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain.

Do not stop using Pregeb D 75/30 Capsule suddenly as it can cause withdrawal symptoms. Your doctor will gradually reduce the dose based on your clinical condition.

Seek medical attention immediately if you notice any depressive thoughts while using Pregeb D 75/30 Capsule . Your doctor may change the dose or medicine to treat your condition.

Neuropathic pain/ peripheral neuropathy is pain that occurs when the nervous system is not working properly or is damaged.

Drug-Drug Interactions Checker List

  • TRAMADOL
  • FLUOXETINE
  • MOCLOBEMIDE
  • VENLAFAXINE
  • AMITRIPTYLINE

Special Advise

  • Do not stop taking Pregeb D 75/30 Capsule suddenly, as it may cause withdrawal symptoms.
  • Do frequent blood tests to check your fasting blood glucose, HbA1c, and total cholesterol (TC) levels to reduce any serious side effects.

Disease/Condition Glossary

Diabetic Neuropathy: Diabetic neuropathic pain/diabetic neuropathy is a condition causing moderate to severe pain due to damage of nerves in the thigh, hip, buttock and leg regions. Symptoms may include tingling, shooting pain, burning, or even an electric shock sensation. It mainly occurs in patients suffering from Type II Diabetes.

Fibromyalgia: It is a chronic condition with moderate pain and tenderness of the muscle all over the body. It mainly occurs due to physical or psychological stress. Symptoms may include fatigue, tiredness, trouble sleeping, anxiety, headache and depression.

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