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Reviewed By Sunny S , MBBS
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Composition

PRIMIDONE-12.5MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Prolet 12.5 Tablet 15's

Prolet 12.5 Tablet 15's belongs to the group of neurological medication called 'anticonvulsant' used to control various epileptic conditions (fits), prevent seizures and treat shaking attacks (essential tremor). Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain leading to seizures, unusual behaviour, and loss of awareness. Prolet 12.5 Tablet 15's is ineffective for treating absence (petit mal) seizures.

Prolet 12.5 Tablet 15's contains 'Primidone', which increases the activity of a chemical messenger (GABA) that suppresses the brain's excessive and abnormal activity of nerve cells. Our brain cells (neurons) work by firing at a certain rate to function normally. However, during an epileptic attack or seizure, our neurons are forced to work rapidly compared to normal conditions. Prolet 12.5 Tablet 15's prevents neurons from working at a very fast speed, thereby preventing all brain cells from firing together rapidly in an uncontrolled way. As a result, episodes of seizures are stopped at their initial point only. 

Take Prolet 12.5 Tablet 15's with or without food. You are advised to take Prolet 12.5 Tablet 15's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as nausea, headache, vomiting, drowsiness, vertigo, visual impairment, low energy, impaired coordination, and nystagmus (involuntary eye movement). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition, effectually continue taking Prolet 12.5 Tablet 15's for as long as your doctor has prescribed it. Please do not skip any doses or stop taking Prolet 12.5 Tablet 15's suddenly without consulting your doctor, as it may lead to increased seizures. Avoid taking Prolet 12.5 Tablet 15's if you are pregnant or breastfeeding unless prescribed. Prolet 12.5 Tablet 15's should not be given to children unless prescribed by a doctor. Avoid alcohol consumption while taking Prolet 12.5 Tablet 15's as it might increase side effects. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Prolet 12.5 Tablet 15's

Epilepsy (fits)

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew it.Syrup: Take the prescribed dose by mouth using the measuring cup/dosing syringe. Shake the bottle well before use.

Medicinal Benefits

Prolet 12.5 Tablet 15's belongs to the group of anticonvulsant medicines. It contains Primidone used to control epilepsy (fits). Prolet 12.5 Tablet 15's is also used to control and prevent fits during or after a severe head injury or brain surgery. Prolet 12.5 Tablet 15's is also used to treat trigeminal neuralgia (facial nerve pain). Prolet 12.5 Tablet 15's works by controlling overactivity of the brain that causes seizures (fits). Thereby, Prolet 12.5 Tablet 15's helps in controlling epileptic fits involving spasms of the muscles and jerking.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Prolet 12.5 Tablet 15's

  • Headache
  • Nausea
  • Dizziness
  • Drowsiness
  • Low energy
  • Vomiting
  • Vertigo
  • Visual impairment
  • Impaired coordination
  • Nystagmus (involuntary eye movement)

Drug Warnings

Do not take Prolet 12.5 Tablet 15's if you are allergic to any of its contents. Do not skip doses or stop taking Prolet 12.5 Tablet 15's suddenly without consulting your doctor, as Prolet 12.5 Tablet 15's may cause increased seizures. Talk to your doctor if you have heart, kidney, or liver problems. Avoid taking Prolet 12.5 Tablet 15's if you are pregnant or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Prolet 12.5 Tablet 15's as it might cause unpleasant side effects. Prolet 12.5 Tablet 15's should not be used by children unless prescribed. Let your doctor know if you have diabetes, as intake of Prolet 12.5 Tablet 15's affects the blood sugar level. Intake of Prolet 12.5 Tablet 15's may cause dizziness, so be cautious while driving or operating heavy machinery.

Drug-Drug Interactions

verifiedApollotooltip
PrimidoneVoriconazole
Critical
PrimidonePirfenidone
Critical

Drug-Drug Interactions

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PrimidoneVoriconazole
Critical
How does the drug interact with Prolet 12.5 Tablet:
Taking voriconazole together with Prolet 12.5 Tablet may reduce the blood levels of voriconazole, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Voriconazole and Prolet 12.5 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PrimidonePirfenidone
Critical
How does the drug interact with Prolet 12.5 Tablet:
Coadministration of pirfenidone with Prolet 12.5 Tablet can reduce levels and the effects of pirfenidone.

How to manage the interaction:
Although there is an interaction between pirfenidone and Prolet 12.5 Tablet, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneRanolazine
Critical
How does the drug interact with Prolet 12.5 Tablet:
Coadministration of ranolazine with Prolet 12.5 Tablet can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between Prolet 12.5 Tablet and Ranolazine, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidonePraziquantel
Critical
How does the drug interact with Prolet 12.5 Tablet:
Taking praziquantel with Prolet 12.5 Tablet can lower the levels of praziquantel in your blood, which leads to a decreased therapeutic effect.

How to manage the interaction:
Taking Prolet 12.5 Tablet with Praziquantel is not recommended. Please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PrimidoneLurasidone
Critical
How does the drug interact with Prolet 12.5 Tablet:
Co-administration of lurasidone with Prolet 12.5 Tablet may result in significantly lower blood levels of lurasidone, making the medication less effective or ineffective in treating your illness.

How to manage the interaction:
There is an interaction between Lurasidone and Prolet 12.5 Tablet, so it is not recommended; it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneBoceprevir
Critical
How does the drug interact with Prolet 12.5 Tablet:
Coadministration of boceprevir with Prolet 12.5 Tablet may decrease the blood levels of boceprevir, which may make it less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Prolet 12.5 Tablet and boceprevir, they can be taken together if your doctor advises. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PrimidoneIsavuconazole
Critical
How does the drug interact with Prolet 12.5 Tablet:
Taking isavuconazole with Prolet 12.5 Tablet may decrease the blood levels of isavuconazole and reduce its effectiveness.

How to manage the interaction:
Taking isavuconazole with Prolet 12.5 Tablet is not recommended, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneRitonavir
Critical
How does the drug interact with Prolet 12.5 Tablet:
Taking ritonavir and Prolet 12.5 Tablet may decrease the blood levels of ritonavir.

How to manage the interaction:
Taking Prolet 12.5 Tablet with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneDaclatasvir
Critical
How does the drug interact with Prolet 12.5 Tablet:
Coadministration of daclatasvir with Prolet 12.5 Tablet may decrease the blood levels of daclatasvir, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Prolet 12.5 Tablet and Daclatasvir, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneApremilast
Severe
How does the drug interact with Prolet 12.5 Tablet:
Coadministration of apremilast with Prolet 12.5 Tablet may decrease the blood levels of apremilast, which may make apremilast less effective in treating.

How to manage the interaction:
Although there is an interaction between Prolet 12.5 Tablet and Apremilast, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Following a ketogenic diet (low in carbohydrates and high in fat) is recommended.
  • Meditation, walking, involving in a task, and smelling a strong odour are a few self-control methods to prevent seizures.
  • Acupuncture therapy may also be helpful.
  • Rest properly. Avoid stress by doing meditation or yoga.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Prolet 12.5 Tablet 15's Substitute

Substitutes safety advice
  • Prolet-12.5mg Tablet 10's

    by AYUR

    9.50per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FLUINDIONE
  • PHENINDIONE
  • WARFARIN
  • PHENYTOIN
  • FELBAMATE
  • VALPROIC ACID
  • CARBAMAZEPINE
  • LAMOTRIGINE
  • OXCARBAZEPINE
  • DEXAMETHASONE
  • CYCLOSPORINE
  • TACROLIMUS
  • SIROLIMUS
  • EVEROLIMUS
  • PREDNISONE
  • LURASIDONE
  • CYCLOPHOSPHAMIDE
  • LOPINAVIR
  • BOCEPREVIR
  • COBICISTAT
  • THEOPHYLLINE
  • MONTELUKAST

Special Advise

  • Your doctor may advise you to get regular blood tests to check for any abnormality of blood and test the amount of Prolet 12.5 Tablet 15's in your blood. 
  • Monitor your blood sugar level regularly while taking Prolet 12.5 Tablet 15's.

Disease/Condition Glossary

Epilepsy: It is a central nervous system disorder in which brain activity becomes abnormal, leading to rapid fits/seizure episodes with unusual behaviour and loss of awareness. Fits/Seizure is a sudden rush of electrical activity in the brain. Lack of sleep, high fever, stress, bright lights, caffeine, certain medicines, alcohol, and skipping meals/overeating are a few of the most common triggers for seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders.

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