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Composition :

PRIMIDONE-50MG

Manufacturer/Marketer :

Alteus Biogenics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Prolet-50 Tablet

Prolet-50 Tablet belongs to the group of neurological medication called 'anticonvulsant' used to control various epileptic conditions (fits), prevent seizures and treat shaking attacks (essential tremor). Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain leading to seizures, unusual behaviour, and loss of awareness. Prolet-50 Tablet is ineffective for treating absence (petit mal) seizures.

Prolet-50 Tablet contains 'Primidone', which increases the activity of a chemical messenger (GABA) that suppresses the brain's excessive and abnormal activity of nerve cells. Our brain cells (neurons) work by firing at a certain rate to function normally. However, during an epileptic attack or seizure, our neurons are forced to work rapidly compared to normal conditions. Prolet-50 Tablet prevents neurons from working at a very fast speed, thereby preventing all brain cells from firing together rapidly in an uncontrolled way. As a result, episodes of seizures are stopped at their initial point only. 

Take Prolet-50 Tablet with or without food. You are advised to take Prolet-50 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as nausea, headache, vomiting, drowsiness, vertigo, visual impairment, low energy, impaired coordination, and nystagmus (involuntary eye movement). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition, effectually continue taking Prolet-50 Tablet for as long as your doctor has prescribed it. Please do not skip any doses or stop taking Prolet-50 Tablet suddenly without consulting your doctor, as it may lead to increased seizures. Avoid taking Prolet-50 Tablet if you are pregnant or breastfeeding unless prescribed. Prolet-50 Tablet should not be given to children unless prescribed by a doctor. Avoid alcohol consumption while taking Prolet-50 Tablet as it might increase side effects. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Prolet-50 Tablet

Epilepsy (fits)

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew it.Syrup: Take the prescribed dose by mouth using the measuring cup/dosing syringe. Shake the bottle well before use.

Medicinal Benefits

Prolet-50 Tablet belongs to the group of anticonvulsant medicines. It contains Primidone used to control epilepsy (fits). Prolet-50 Tablet is also used to control and prevent fits during or after a severe head injury or brain surgery. Prolet-50 Tablet is also used to treat trigeminal neuralgia (facial nerve pain). Prolet-50 Tablet works by controlling overactivity of the brain that causes seizures (fits). Thereby, Prolet-50 Tablet helps in controlling epileptic fits involving spasms of the muscles and jerking.

Storage

Store in a cool and dry place away from sunlight
Side effects of Prolet-50 Tablet
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.

Drug Warnings

Do not take Prolet-50 Tablet if you are allergic to any of its contents. Do not skip doses or stop taking Prolet-50 Tablet suddenly without consulting your doctor, as Prolet-50 Tablet may cause increased seizures. Talk to your doctor if you have heart, kidney, or liver problems. Avoid taking Prolet-50 Tablet if you are pregnant or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Prolet-50 Tablet as it might cause unpleasant side effects. Prolet-50 Tablet should not be used by children unless prescribed. Let your doctor know if you have diabetes, as intake of Prolet-50 Tablet affects the blood sugar level. Intake of Prolet-50 Tablet may cause dizziness, so be cautious while driving or operating heavy machinery.

Drug-Drug Interactions

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PrimidoneDaclatasvir
Critical
PrimidoneIsavuconazole
Critical

Drug-Drug Interactions

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PrimidoneDaclatasvir
Critical
How does the drug interact with Prolet-50 Tablet:
Coadministration of daclatasvir with Prolet-50 Tablet may decrease the blood levels of daclatasvir, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Prolet-50 Tablet and Daclatasvir, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneIsavuconazole
Critical
How does the drug interact with Prolet-50 Tablet:
Taking isavuconazole with Prolet-50 Tablet may decrease the blood levels of isavuconazole and reduce its effectiveness.

How to manage the interaction:
Taking isavuconazole with Prolet-50 Tablet is not recommended, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneRanolazine
Critical
How does the drug interact with Prolet-50 Tablet:
Coadministration of ranolazine with Prolet-50 Tablet can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between Prolet-50 Tablet and Ranolazine, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneLurasidone
Critical
How does the drug interact with Prolet-50 Tablet:
Co-administration of lurasidone with Prolet-50 Tablet may result in significantly lower blood levels of lurasidone, making the medication less effective or ineffective in treating your illness.

How to manage the interaction:
There is an interaction between Lurasidone and Prolet-50 Tablet, so it is not recommended; it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneBoceprevir
Critical
How does the drug interact with Prolet-50 Tablet:
Coadministration of boceprevir with Prolet-50 Tablet may decrease the blood levels of boceprevir, which may make it less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Prolet-50 Tablet and boceprevir, they can be taken together if your doctor advises. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PrimidoneVoriconazole
Critical
How does the drug interact with Prolet-50 Tablet:
Taking voriconazole together with Prolet-50 Tablet may reduce the blood levels of voriconazole, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Voriconazole and Prolet-50 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PrimidonePirfenidone
Critical
How does the drug interact with Prolet-50 Tablet:
Coadministration of pirfenidone with Prolet-50 Tablet can reduce levels and the effects of pirfenidone.

How to manage the interaction:
Although there is an interaction between pirfenidone and Prolet-50 Tablet, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneRitonavir
Critical
How does the drug interact with Prolet-50 Tablet:
Taking ritonavir and Prolet-50 Tablet may decrease the blood levels of ritonavir.

How to manage the interaction:
Taking Prolet-50 Tablet with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidonePraziquantel
Critical
How does the drug interact with Prolet-50 Tablet:
Taking praziquantel with Prolet-50 Tablet can lower the levels of praziquantel in your blood, which leads to a decreased therapeutic effect.

How to manage the interaction:
Taking Prolet-50 Tablet with Praziquantel is not recommended. Please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PrimidoneAmlodipine
Severe
How does the drug interact with Prolet-50 Tablet:
Using amlodipine and Prolet-50 Tablet together may lower amlodipine blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of amlodipine with Prolet-50 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Following a ketogenic diet (low in carbohydrates and high in fat) is recommended.
  • Meditation, walking, involving in a task, and smelling a strong odour are a few self-control methods to prevent seizures.
  • Acupuncture therapy may also be helpful.
  • Rest properly. Avoid stress by doing meditation or yoga.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Prolet-50 Tablet Substitute

Substitutes safety advice
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    7.20per tablet
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    by AYUR

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  • Epiad 50 Tablet 10's

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  • Epiprimid-50 Tablet 10's

    by Others

    9.45per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Prolet-50 Tablet works by controlling overactivity of the brain that causes seizures (fits). Thereby, Prolet-50 Tablet helps in controlling epileptic fits involving spasms of the muscles and jerking.

Prolet-50 Tablet can make birth control pills less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.

Please do not stop taking Prolet-50 Tablet without consulting your doctor as it may cause increased seizures. Continue taking Prolet-50 Tablet for as long as your doctor prescribes it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Prolet-50 Tablet .

Yes, Prolet-50 Tablet may cause swelling in the gums. Brush and floss your teeth daily; visit your dentist if you experience this problem regularly.

You should not take Prolet-50 Tablet if you have liver disease, kidney disease, porphyria (an inherited disease that affects haemoglobin biosynthesis), alcohol dependence and suicidal thoughts.

Primidone may affect the breakdown of blood sugar/glucose and may prevent the release of insulin, thereby leading to high blood sugar. This is important if you have diabetes. So, contact a doctor before using Prolet-50 Tablet in this condition.

Drug-Drug Interactions Checker List

  • FLUINDIONE
  • PHENINDIONE
  • WARFARIN
  • PHENYTOIN
  • FELBAMATE
  • VALPROIC ACID
  • CARBAMAZEPINE
  • LAMOTRIGINE
  • OXCARBAZEPINE
  • DEXAMETHASONE
  • CYCLOSPORINE
  • TACROLIMUS
  • SIROLIMUS
  • EVEROLIMUS
  • PREDNISONE
  • LURASIDONE
  • CYCLOPHOSPHAMIDE
  • LOPINAVIR
  • BOCEPREVIR
  • COBICISTAT
  • THEOPHYLLINE
  • MONTELUKAST

Special Advise

  • Your doctor may advise you to get regular blood tests to check for any abnormality of blood and test the amount of Prolet-50 Tablet in your blood. 
  • Monitor your blood sugar level regularly while taking Prolet-50 Tablet .

Disease/Condition Glossary

Epilepsy: It is a central nervous system disorder in which brain activity becomes abnormal, leading to rapid fits/seizure episodes with unusual behaviour and loss of awareness. Fits/Seizure is a sudden rush of electrical activity in the brain. Lack of sleep, high fever, stress, bright lights, caffeine, certain medicines, alcohol, and skipping meals/overeating are a few of the most common triggers for seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders.

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