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Written By Divya L , PharmaD
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Meethi Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

About Promygra 20 Tablet

Promygra 20 Tablet belongs to the class of 'anti-migraine drugs' primarily used to treat migraine. Migraine is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Its symptoms include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

Promygra 20 Tablet consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. It is also used to treat vertigo (spinning sensation).

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Promygra 20 Tablet include dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting Promygra 20 Tablet. Promygra 20 Tablet may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking Promygra 20 Tablet if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with Promygra 20 Tablet as it could lead to increased drowsiness.

Uses of Promygra 20 Tablet

Migraine.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, crush or break it.

Medicinal Benefits

Promygra 20 Tablet is used to treat migraine. It consists of 'Propranolol' and 'Flunarizine'. Propranolol is a beta-blocker and has anxiolytic (anxiety-reducing), anti-arrhythmic, and antihypertensive properties. It works by lowering cerebral (brain) blood flow and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation. It reduces the severity and frequency of migraine headaches. Flunarizine is a channel blocker that improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. 

Storage

Keep Promygra 20 Tablet out of sight and reach of children.

Drug Warnings

Inform your doctor if you have any history of liver or kidney diseases, breathing problems (asthma, bronchitis, emphysema), diabetes, heart failure, heart rhythm problems (sinus bradycardia, Wolff-Parkinson-White syndrome, atrioventricular block), overactive thyroid, blood circulation problems (Raynaud's disease), adrenal gland tumour (pheochromocytoma), depression, metabolic acidosis (excess acid in the blood), and myasthenia gravis (muscle weakness) before starting Promygra 20 Tablet. Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you Promygra 20 Tablet. Avoid consuming alcohol along with Promygra 20 Tablet as it could lead to increased dizziness and drowsiness.

Drug-Drug Interactions

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PropranololSaquinavir
Severe

Drug-Drug Interactions

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How does the drug interact with Promygra 20 Tablet:
Coadministration of thioridazine with Promygra 20 Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Promygra 20 Tablet and thioridazine, they can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, and shortness of breath contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololSaquinavir
Severe
How does the drug interact with Promygra 20 Tablet:
Using saquinavir together with Promygra 20 Tablet increases the risk of irregular heart rhythm due to the additive effect.

How to manage the interaction:
Although taking Promygra 20 Tablet together with Saquinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, sudden dizziness, fainting, slow pulse, or irregular heartbeat. Do not stop using any medication without consulting a doctor.
PropranololIsoetarine
Severe
How does the drug interact with Promygra 20 Tablet:
Using Promygra 20 Tablet together with isoetharine may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Promygra 20 Tablet can sometimes cause breathing problems.

How to manage the interaction:
Although taking Promygra 20 Tablet together with Isoetarine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promygra 20 Tablet:
Taking Promygra 20 Tablet with Labetalol can potentially enhance the effects of orthostatic hypotension (low blood pressure that happens when standing after sitting or lying down).

How to manage the interaction:
Although taking Promygra 20 Tablet together with Labetalol can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience lightheadedness or dizziness upon standing, blurred vision, weakness, fainting, or confusion. Do not discontinue any medicine without consulting a doctor.
How does the drug interact with Promygra 20 Tablet:
Using Promygra 20 Tablet and salbutamol together can reduce the effects or increase the risk of narrowing of the airways.

How to manage the interaction:
The combined use of Promygra 20 Tablet and salbutamol can lead to an interaction, but they can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promygra 20 Tablet:
Co-administration of Bisoprolol with Promygra 20 Tablet may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there may be an interaction, bisoprolol can be taken with Promygra 20 Tablet if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promygra 20 Tablet:
Coadministration of Aminophylline with Promygra 20 Tablet together can make Promygra 20 Tablet less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Promygra 20 Tablet can cause an interaction. However, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PropranololBitolterol
Severe
How does the drug interact with Promygra 20 Tablet:
Using Promygra 20 Tablet together with bitolterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Promygra 20 Tablet can sometimes cause breathing problems.

How to manage the interaction:
Taking Promygra 20 Tablet with Bitolterol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promygra 20 Tablet:
Coadministration of Promygra 20 Tablet and levosalbutamol can increase the risk of breathing problems.

How to manage the interaction:
Although there is an interaction between Promygra 20 Tablet and levosalbutamol, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promygra 20 Tablet:
Taking Promygra 20 Tablet and Diltiazem together increases the risk of side effects.

How to manage the interaction:
Although taking Promygra 20 Tablet together with Diltiazem can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not stop using any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. Instead, eat a healthy diet and do regular exercise to avoid weight gain caused due to Promygra 20 Tablet.
  • Avoid loud music, extreme temperatures, bright lights, and noisy places as it can increase headache.
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine to relieve headaches.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Promygra 20 Tablet is a combination of two drugs: Propranolol and Flunarizine. Promygra 20 Tablet treats migraine by reducing the blood flow to the brain, and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation.

Promygra 20 Tablet may sometimes cause weight gain during its prolonged use. It is always advised to maintain a well-balanced, healthy diet and exercise regularly.

Promygra 20 Tablet does not work for a sudden migraine attack. It is helpful in only preventing new episodes of migraine headaches. Please let your doctor know if you have sudden attacks to be prescribed other suitable medications.

Promygra 20 Tablet is contraindicated in asthma, slow heart rate, abnormal heart rhythms, heart conditions like AV (Atrioventricular) block or sick sinus syndrome, depression, and Parkinson's disease. Please consult your doctor before starting Promygra 20 Tablet if you have a medical history.

Your doctor will prescribe Promygra 20 Tablet to prevent any new episodes of migraine. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of migraine. Promygra 20 Tablet also contains Propranolol, and its sudden withdrawal may cause sweating, shaking, irregular heartbeat, and worsening of underlying angina or heart attack. Hence, do not stop using Promygra 20 Tablet unless advised by your doctor.

Drug-Drug Interactions Checker List

  • ALPRAZOLAM
  • QUETIAPINE
  • ARIPIPRAZOLE
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • SERTRALINE
  • DULOXETINE
  • FLUOXETINE
  • CARBAMAZEPINE
  • PHENYTOIN

Special Advise

  • Let your doctor know that you are taking Promygra 20 Tablet if you are undergoing any medical tests.
  • Beta-blockers like Propranolol can mask hypoglycaemia symptoms (low blood sugar) or hyperthyroidism (high thyroid levels).
  • It is advised to inform your doctor if you have diabetes or thyroid disease before using Promygra 20 Tablet.
  • Beta-blockers can also cause changes in serum lipid profiles. Patients with pre-existing hyperlipidaemia (high lipid levels) should be closely monitored if using Promygra 20 Tablet.

Disease/Condition Glossary

Migraine: It is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Symptoms of migraine may include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound. Migraine can be triggered by various factors like foods (eggs, tomatoes, onions, dairy products, wheat, pasta, citrus fruits, nitrites found in foods, alcohol, and red wine), hormonal changes, sleep changes, stress, loud noises, and medications.

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