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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Composition :

ALPROSTADIL-500MCG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Prostacel 500 mcg Injection

Prostacel 500 mcg Injection belongs to the class of medicine called vasodilators. It is primarily used in the treatment of erectile dysfunction. Erectile dysfunction, also known as impotence, is defined as the difficulty of keeping a hard and erect penis that is firm enough and suitable for sexual activity. Symptoms may include less sexual desire, trouble getting and keeping an erection, and pain during intercourse. Prostacel 500 mcg Injection is also used as an adjunct to other diagnostic tests in the diagnosis of erectile dysfunction.

Prostacel 500 mcg Injection contains ‘Alprostadil, which belongs to the class of vasodilators. It works by relaxing the blood vessels in the penis; and allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction.

Prostacel 500 mcg Injection may cause certain side effects such as pain or aching in the penis, breakage of the needle, burning sensation in the opening of the urinary opening of the penis, redness of the penis, and prolonged erection. Most of these side effects do not require medical attention and will resolve gradually over time. However, if you experience these side effects persistently, consult your doctor immediately. Prostacel 500 mcg Injection should be administered as prescribed by your doctor. Before administration, read the label carefully.

Prostacel 500 mcg Injection should be avoided if you are allergic to it or other components present in it. This medicine is contraindicated in conditions such as sickle cell anemia or sickle cell trait, multiple myeloma, leukemia, cavernosal fibrosis, and penile implants, as it can lead to serious side effects. Prostacel 500 mcg Injection is only recommended for use in men; hence, the use of this medicine in women and children should be avoided. Inform your doctor if you have/had heart problems or stroke, low blood pressure or uncontrolled high blood pressure, liver/kidney and penile fibrosis. Prostacel 500 mcg Injection may cause dizziness, so avoid driving, as it can make you dizzy. Avoid consuming alcohol as it may cause increased dizziness and other unusual side effects. 

Uses of Prostacel 500 mcg Injection

Erectile dysfunction (impotence).

Directions for Use

Prostacel 500 mcg Injection is intended for the Intracavenosal/Urethral route only. It should be administered as prescribed by your doctor. Follow all the instructions provided in the leaflet or discuss the administration procedure with your doctor. How to use: Wash and dry your hands before administration. Remove the syringe and the needle from the wrap without touching it. Then remove the syringe cap, attach the needle to the syringe and turn it in clockwise. Now remove the vial cap and wipe the rubber stopper with alcohol swap. Later, remove the needle cover and push the needle into the diluent. Adjust the reading on the syringe and remove the liquid from the vail. Tap the syringe barrel to remove any air bubbles present. Now inject the liquid on the top view of the penis. Be careful while removing the liquid as there may be chances of breakage.

Medicinal Benefits

Prostacel 500 mcg Injection contains Alprostadil, which belongs to the class of vasodilators. It works by relaxing the blood vessels in the penis; and allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction.

Storage

Store in a cool and dry place away from sunlight
Side effects of Prostacel 500 mcg Injection
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here's a comprehensive approach to managing medication-triggered high blood pressure (hypertension):
  • Inform your doctor if you experience high blood pressure symptoms after starting a new medication or changing your medication regimen.
  • To reduce high blood pressure symptoms, your doctor may change your medication regimen or dose.
  • Monitor your blood pressure regularly to track changes and potential side effects.
  • Make lifestyle changes, such as following a healthy diet, exercising regularly, and reducing sodium intake.
  • Consider incorporating stress-reducing activities, like meditation or deep breathing exercises, into your daily routine.
  • Create a personalized plan with your doctor to manage high blood pressure, which may include additional medications, therapies, or lifestyle modifications.
  • Follow up with your doctor on a frequent basis to assess progress, change treatment plans, and address any concerns or issues.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.

Drug Warnings

Prostacel 500 mcg Injection should be avoided if you are allergic to it or its other components. This medicine is contraindicated in conditions such as sickle cell anemia or sickle cell trait, multiple myeloma, leukemia, cavernosal fibrosis, Peyronie’s disease or penile implants, as it can lead to serious side effects. Prostacel 500 mcg Injection is only recommended for use in men; hence, the use of this medicine in women and children should be avoided. Inform your doctor if you have/had heart problems or stroke, low blood pressure or uncontrolled high blood pressure, liver/kidney and penile fibrosis. Prostacel 500 mcg Injection may cause dizziness, so avoid driving, as it can make you dizzy. Avoid consuming alcohol, which might cause increased dizziness and other unusual side effects. 

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintaining a healthy weight, eating a balanced diet, and regular exercising may help you manage erectile dysfunction. 
  • Avoid alcohol consumption as it may temporarily impair your ability to get an erection.
  • Avoid the usage of tobacco.
  • Share intimate time with your partner.
  • Stay sexually active to prevent further problems with erectile dysfunction.

Habit Forming

No

Therapeutic Class

VASODILATORS

Prostacel 500 mcg Injection Substitute

Substitutes safety advice
  • Alpostin 500 mcg Injection 1 ml

    by Others

    5641.70per tablet
  • Alpostadil Injection 1 ml

    by Others

    6411.73per tablet
  • Prostal 500Mg Inj

    by AYUR

    4689.17per tablet

Drug-Diseases Interactions

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ALPROSTADIL-500MCGRespiratory failure, not elsewhere classified
Severe
ALPROSTADIL-500MCGHypotension
Moderate

Drug-Diseases Interactions

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ALPROSTADIL-500MCGRespiratory failure, not elsewhere classified
Severe
How does the disease interact with Prostacel 500 mcg Injection:
Prostacel 500 mcg Injection injection should not be used in neonates with respiratory distress syndrome.

How to manage the interaction:
Prostacel 500 mcg Injection is contraindicated in newborns with respiratory distress syndrome (breathing disorder). Prostacel 500 mcg Injection should be used where ventilatory assistance is immediately available.
ALPROSTADIL-500MCGHypotension
Moderate
How does the disease interact with Prostacel 500 mcg Injection:
Prostacel 500 mcg Injection should be administered cautiously in patients with hypotension.

How to manage the interaction:
Prostacel 500 mcg Injection may increase the risk of hypotension (low blood pressure). Hence, Prostacel 500 mcg Injection should be used with caution in hypotension patients.
ALPROSTADIL-500MCGHaemorrhage, not elsewhere classified
Moderate
How does the disease interact with Prostacel 500 mcg Injection:
Platelet aggregation is prevented with Prostacel 500 mcg Injection. When administering Prostacel 500 mcg Injection injection to newborns who have a tendency to haemorrhage, caution is advised.

How to manage the interaction:
Prostacel 500 mcg Injection inhibits platelet aggregation (platelets clump together to form blood clots). Hence, Prostacel 500 mcg Injection should be used with caution in neonates with bleeding tendencies.

FAQs

No, do not take Prostacel 500 mcg Injection with nitrates. Taking Prostacel 500 mcg Injection with medicines used to treat angina/chest pain, such as nitrates/nitroglycerin, may cause severe lowering of blood pressure. You are advised not to take Prostacel 500 mcg Injection if you are taking nitrates or have a history of heart attack/stroke.

Prostacel 500 mcg Injection works by relaxing the blood vessels in the penis, allowing blood to flow into the penis when the person is sexually excited.

Drug-Drug Interactions Checker List

  • AMLODIPINE
  • LISINOPRIL
  • TAMSULOSIN
  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERYTHROMYCIN
  • PHENOBARBITAL
  • PHENYTOIN
  • CARBAMAZEPINE
  • RIFAMPICIN

Special Advise

  • Do not take Prostacel 500 mcg Injection more than once a day. Take Prostacel 500 mcg Injection as prescribed by the doctor.
  • Talk to your doctor if the erection persists for greater than four hours.
  • Prostacel 500 mcg Injection is only intended for use in men. Avoid using it for women and children.
  • Intended to be administered through the intracavernosal route only. Hence avoid using it for IM or IV route.

Disease/Condition Glossary

Erectile dysfunction: Erectile dysfunction, also known as impotence, is defined as the difficulty of keeping a hard and erect penis that is firm enough and suitable for sexual activity. It could be a sign of physical or psychological conditions such as fear of sexual failure, anxiety, depression, low self-esteem, or stress. Certain health-related factors such as smoking, drinking, being overweight, being physically inactive, and high blood pressure also contribute to erectile dysfunction. Symptoms of erectile dysfunction include difficulty in getting an erection, difficulty in maintaining the erection during intercourse and decreased sexual desire.

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