Pulmofree 10 mg Injection 12.5 ml

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Veda Maddala , M Pharmacy

MRP ₹2000

(Inclusive of all Taxes)

₹300.0 Cashback (15%)

Provide Delivery Location

Non returnable*

Know More

COD available

Online payment accepted

Prescription drug

Whats That

About Pulmofree 10 mg Injection 12.5 ml

Pulmofree 10 mg Injection 12.5 ml belongs to the group of medicines called phosphodiesterase-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs), to improve the ability to exercise and to slow down clinical worsening.

Pulmofree 10 mg Injection 12.5 ml contains 'Sildenafil' that relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.

In some cases, Pulmofree 10 mg Injection 12.5 ml may cause side effects such as headache, indigestion, flushing, insomnia, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Pulmofree 10 mg Injection 12.5 ml if you are allergic to any of the components or if you are taking nitrate medicines or riociguat (a drug used to treat pulmonary hypertension). Pulmofree 10 mg Injection 12.5 ml is not recommended for use in children. Consult your doctor if you experience hearing or visual impairment.

Uses of Pulmofree 10 mg Injection 12.5 ml

Pulmonary arterial hypertension (PAH)

Directions for Use

Pulmofree 10 mg Injection 12.5 ml will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Pulmofree 10 mg Injection 12.5 ml belongs to the group of medicines called phosphodiesterase type-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs) to improve the ability to exercise and to slow down clinical worsening. Pulmofree 10 mg Injection 12.5 ml relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.

Storage

Keep Pulmofree 10 mg Injection 12.5 ml out of reach and sight of children.

Side effects of Pulmofree 10 mg Injection 12.5 ml

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Reddening Of The Face

Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:

Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Trouble Falling/ Staying Asleep

Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:

Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
Try relaxing techniques like deep breathing, mindfulness meditation and any others.
Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Redness Of The Skin

Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:

Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Shortness Of Breath

Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):

Tell your doctor immediately if you experience shortness of breath after taking medication.
Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Stuffy Nose

Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide

Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.

Drug Warnings

Do not take Pulmofree 10 mg Injection 12.5 ml if you are allergic to any of the components, if you are taking medicines called nitrates which are used to treat angina or chest pain or guanylate cyclase stimulator medicines (medicines used to treat heart failure and PAH). Inform your doctor if you have/had heart problems such as angina, heart attack, irregular heartbeat, or heart failure, blood circulation problems, low blood pressure, eye or ear problems, sickle cell anaemia (an abnormality of red blood cells), multiple myeloma (cancer of bone marrow) or leukaemia (cancer of blood cells), stomach ulcer, bleeding problems, problems with the shape of the penis or Peyronie's disease (a condition that causes painful erections).

Drug-Drug Interactions

SildenafilSaquinavir

Critical

SildenafilAmyl nitrite

Critical

Drug-Drug Interactions

Login/Sign Up

SildenafilSaquinavir

Critical

How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Saquinavir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and side effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Saquinavir and Pulmofree 10 mg Injection 12.5 ml together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

SildenafilAmyl nitrite

Critical

How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Combining Amyl nitrite and Pulmofree 10 mg Injection 12.5 ml can increase the risk or severity of lower blood pressure.

How to manage the interaction:
Taking Amyl nitrite and Pulmofree 10 mg Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken only when advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

SildenafilAtazanavir

Critical

How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Combining Atazanavir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and side effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Atazanavir and Pulmofree 10 mg Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

SildenafilIndinavir

Critical

How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Indinavir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and side effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Indinavir and Pulmofree 10 mg Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

SildenafilTelaprevir

Critical

How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Combining Telaprevir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Telaprevir and Pulmofree 10 mg Injection 12.5 ml together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

SildenafilAmprenavir

Critical

How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Amprenavir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Amprenavir and Pulmofree 10 mg Injection 12.5 ml together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

SildenafilRiociguat

Critical

How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Co-administration of Pulmofree 10 mg Injection 12.5 ml with Riociguat may lower the blood pressure.

How to manage the interaction:
Taking Riociguat and Pulmofree 10 mg Injection 12.5 ml together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

SildenafilDarunavir

Critical

How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Combining Darunavir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Darunavir and Pulmofree 10 mg Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

SildenafilIsosorbide dinitrate

Critical

How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Isosorbide dinitrate and Pulmofree 10 mg Injection 12.5 ml can increase the risk of low blood pressure.

How to manage the interaction:
Taking Isosorbide dinitrate and Pulmofree 10 mg Injection 12.5 ml together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

SildenafilNitroprusside

Critical

How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Pulmofree 10 mg Injection 12.5 ml with Nitroprusside can increase the risk of developing low blood pressure.

How to manage the interaction:
Taking Pulmofree 10 mg Injection 12.5 ml with Nitroprusside together is generally avoided as it can lead to an interaction, it can be taken only if prescribed by your doctor. If you experience any side effects such as dizziness, lightheadedness, headache, or heart palpitations you should seek immediate medical attention. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

Lower your intake of salt. This helps in reducing the risk of developing oedema.
Include vegetables, fruits, whole grains, lean meats, poultry, fish, and fat-free/low-fat dairy products in your diet.
Avoid canned foods, processed foods, pickled, and frozen food. Instead, consume fresh foods.
Limit consumption of caffeine and alcohol as they can alter blood pressure.
Monitor fluid intake to prevent swelling/fluid retention.

Side Effects of Pulmofree 10 mg Injection 12.5 ml

Headache
Indigestion
Flushing
Insomnia (sleep disorder)
Diarrhoea

Habit Forming

No

Therapeutic Class

PDE5-INHIBITORS

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:45 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

FAQs

How does Pulmofree 10 mg Injection 12.5 ml work?

Pulmofree 10 mg Injection 12.5 ml relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.

Does Pulmofree 10 mg Injection 12.5 ml cause diarrhoea?

Diarrhoea might be a side effect of Pulmofree 10 mg Injection 12.5 ml. Eat non-spicy food and drink fluids if you experience diarrhoea. Consult your doctor if the condition persists or worsens.

Can I take Pulmofree 10 mg Injection 12.5 ml with nitrates?

Do not to take Pulmofree 10 mg Injection 12.5 ml with nitrates. Taking Pulmofree 10 mg Injection 12.5 ml with medicines used to treat angina/chest pain such as nitrates/nitroglycerin may cause severe lowering of blood pressure. Consult your doctor if you have a history of heart attack/stroke.

Does Pulmofree 10 mg Injection 12.5 ml cause low blood pressure?

Pulmofree 10 mg Injection 12.5 ml has vasodilation properties which may cause low blood pressure (hypotension). Therefore, inform your doctor if you have resting hypotension, fluid depletion, autonomic dysfunction (dysfunction of the nerves), or severe left ventricular outflow obstruction.

Does Pulmofree 10 mg Injection 12.5 ml increase the risk of bleeding?

When taken along with vitamin K antagonists, Pulmofree 10 mg Injection 12.5 ml might increase the risk of bleeding. Consult your doctor if you are taking any vitamin K antagonists.

Drug-Drug Interactions Checker List

RIOCIGUAT
RITONAVIR
AMLODIPINE

Disease/Condition Glossary

Pulmonary arterial hypertension (PAH): High blood pressure affects the arteries in the lungs and heart leading to pulmonary arterial hypertension. It occurs due to narrowed or blocked blood vessels which increases the workload on the heart. Symptoms include chest pain, dizziness, fatigue, and swelling in the legs and ankles.