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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

QUETIAPINE-400MG

Manufacturer/Marketer :

Psychotropics India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Quticool-SR 400mg Tablet

Quticool-SR 400mg Tablet belongs to a group of medications called ‘antipsychotics’. It is used in the treatment of bipolar depression, mania and schizophrenia. Bipolar disorder is characterized by manic episodes of excitement or euphoria and depression. Schizophrenia is characterized by symptoms of hallucinations (seeing or hearing things that are not real) and delusions (wrong beliefs).

Quticool-SR 400mg Tablet contains ‘quetiapine’, which is an antipsychotic drug. It acts by blocking dopamine, a hormone in the brain responsible for developing symptoms of schizophrenia and bipolar disorder. Quticool-SR 400mg Tablet  also affects other neurotransmitters in the brain, such as serotonin, and its beneficial effects may also be related to this. Altogether  Quticool-SR 400mg Tablet  rebalances dopamine and serotonin to improve thinking, mood and behaviour.

Quticool-SR 400mg Tablet should be taken as prescribed by the doctor. Common side-effects of Quticool-SR 400mg Tablet are dizziness, drowsiness, headache, dry mouth, abnormal muscle movements such as difficulty moving muscles, tremors and muscle stiffness,  change in cholesterol levels, weight gain, and decrease in haemoglobin (protein in blood that carries oxygen) levels. Additionally, in children and adolescents, swelling of breasts in boys and girls and production of breast milk (due to an increase in prolactin hormone (helps in producing breast milk)) and irregular menstruation can be seen. Please do not stop taking Quticool-SR 400mg Tablet without your doctor’s advice, as it may lead to withdrawal symptoms.

Do not take Quticool-SR 400mg Tablet if you are allergic to quetiapine or any other ingredients present in it. Before taking Quticool-SR 400mg Tablet , inform your doctor if you have problems associated with the liver, kidney or heart. Also, inform your doctor if you have any sleeping difficulties. It is not recommended for use in children under 18 years of age. Tell your doctor immediately if you develop suicidal thoughts, or your depression worsens after taking Quticool-SR 400mg Tablet . Quticool-SR 400mg Tablet contains lactose, so it should not be given to people who are intolerant to some sugars. Tell your doctor if you are pregnant or breastfeeding.

Uses of Quticool-SR 400mg Tablet

Bipolar depression, mania, schizophrenia

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Quticool-SR 400mg Tablet contains ‘quetiapine’ that belongs to the class of antipsychotics. It works by blocking the dopamine receptors preventing the excessive activity of dopamine. Dopamine is a ‘feel-good hormone’ that promotes happiness, excitement and pleasure. It alters brain function, improving mood, thinking ability and social behaviour. It reduces the development of symptoms in patients with schizophrenia, bipolar disorder or other mood disorders. Quticool-SR 400mg Tablet  also has effects on other neurotransmitters in the brain, such as serotonin, and its beneficial effects may also be related to this. Altogether  Quticool-SR 400mg Tablet  rebalances dopamine and serotonin to improve thinking, mood and behaviour.

Storage

Store in a cool and dry place away from sunlight
Side effects of Quticool-SR 400mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
  • Exercise and a healthy diet can help manage high cholesterol, but consult your doctor about medication if lifestyle changes are not enough.
  • Avoid foods high in cholesterol, saturated fat, and trans fats, such as egg yolks, cheese, fried foods, pastries, ice cream, and red meat.
  • Increase your intake of vegetables, fruits, oats, whole grains, lentils, and beans to boost fibre consumption.
  • Include foods rich in monounsaturated fats, like nuts, avocados, olive oil, and oily fish.
  • Exercise regularly for 30 minutes and maintain a healthy weight.
  • Quit smoking and limit excessive alcohol consumption, as both can negatively impact your cholesterol levels.
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Drug Warnings

Do not take Quticool-SR 400mg Tablet if you are allergic to quetiapine or any ingredients present in it. Before taking Quticool-SR 400mg Tablet , inform your doctor if you have low blood pressure, stroke, liver problems, seizures, diabetes, dementia (memory loss), alcohol or drug abuse, sleep apnea (a sleep disorder) and urinary retention. Quticool-SR 400mg Tablet contains lactose, so it should not be given to people with lactose intolerance. Do not abruptly stop taking the medication as it may cause withdrawal symptoms, especially suicidal thoughts in young adults.

Drug-Drug Interactions

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QuetiapineZiprasidone
Critical
QuetiapineMetoclopramide
Critical

Drug-Drug Interactions

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QuetiapineZiprasidone
Critical
How does the drug interact with Quticool-SR 400mg Tablet:
Co-administration of Quticool-SR 400mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Quticool-SR 400mg Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
QuetiapineMetoclopramide
Critical
How does the drug interact with Quticool-SR 400mg Tablet:
Coadministration of metoclopramide with Quticool-SR 400mg Tablet can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Metoclopramide with Quticool-SR 400mg Tablet is generally avoided as it can possibly result in an interaction. They can be taken together if advised by your doctor. However, contact a doctor if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.
QuetiapineDisopyramide
Severe
How does the drug interact with Quticool-SR 400mg Tablet:
Coadministration of disopyramide together with Quticool-SR 400mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between disopyramide and Quticool-SR 400mg Tablet, it can be taken if prescribed by a doctor. If you experience irregular heartbeats, chest pain, sudden dizziness, or trouble breathing, you should call your doctor right away. Do not stop using any medications without a doctor's advice.
QuetiapineFentanyl
Severe
How does the drug interact with Quticool-SR 400mg Tablet:
Coadministration of Quticool-SR 400mg Tablet and fentanyl can increase the risk of side effects such as breathing problems.

How to manage the interaction:
Although taking Fentanyl together with Quticool-SR 400mg Tablet can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you feel dizziness, sleepiness, difficulty concentrating, and impaired judgment. Do not discontinue any medication without consulting a doctor.
QuetiapinePrimidone
Severe
How does the drug interact with Quticool-SR 400mg Tablet:
Coadministration of Quticool-SR 400mg Tablet and primidone can decrease the blood levels of Quticool-SR 400mg Tablet.

How to manage the interaction:
Although taking Primidone and Quticool-SR 400mg Tablet together can evidently cause an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
QuetiapineHydroxychloroquine
Severe
How does the drug interact with Quticool-SR 400mg Tablet:
Coadministration of Quticool-SR 400mg Tablet and hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Quticool-SR 400mg Tablet and hydroxychloroquine can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or shortness of breath, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
QuetiapineTetrabenazine
Severe
How does the drug interact with Quticool-SR 400mg Tablet:
Coadministration of Quticool-SR 400mg Tablet with tetrabenazine an increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Tetrabenazine and Quticool-SR 400mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
QuetiapineRifampicin
Severe
How does the drug interact with Quticool-SR 400mg Tablet:
Taking Quticool-SR 400mg Tablet with rifampin may lower the blood levels of Quticool-SR 400mg Tablet, which may decrease its effectiveness.

How to manage the interaction:
Although taking Rifampicin together with Quticool-SR 400mg Tablet can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
QuetiapineKetoconazole
Severe
How does the drug interact with Quticool-SR 400mg Tablet:
Coadministration of Quticool-SR 400mg Tablet and Ketoconazole may increase the blood levels of Quticool-SR 400mg Tablet.

How to manage the interaction:
Although taking ketoconazole and Quticool-SR 400mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, tiredness, dry mouth, constipation, increased hunger, or weight gain, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
QuetiapineArsenic trioxide
Severe
How does the drug interact with Quticool-SR 400mg Tablet:
Coadministration of Quticool-SR 400mg Tablet with arsenic trioxide can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Co-administration of Arsenic trioxide with Quticool-SR 400mg Tablet can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not take grapefruit or grapefruit juice while using Quticool-SR 400mg Tablet as it may alter the effects of the medicine.
  • Avoid intense exercise as it is harder for the body to cool down when it gets very hot. So, drink plenty of fluids and avoid going out in hot weather.
  • Do not take alcohol as it increases drowsiness and also worsens the disease condition. 
  • Eat healthily and keep a check on your weight regularly.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Quticool-SR 400mg Tablet Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Quticool-SR 400mg Tablet contains 'quetiapine' that works by blocking dopamine receptors in the brain. By inhibiting the synthesis of the dopamine hormone, there will be a decrease in the occurrence of symptoms in patients with schizophrenia and bipolar depression. Quticool-SR 400mg Tablet  also has effects on other neurotransmitters in the brain, such as serotonin, and its beneficial effects may also be related to this. Altogether Quticool-SR 400mg Tablet  rebalances dopamine and serotonin to improve thinking, mood and behaviour.

Quticool-SR 400mg Tablet increases blood pressure. So, it is advisable to monitor your blood pressure while taking Quticool-SR 400mg Tablet frequently.

Quticool-SR 400mg Tablet may cause dizziness and may increase the risk of falls. So, stand up slowly when rising from a sitting or lying position.

Quticool-SR 400mg Tablet should not drive or operate heavy machinery after taking Quticool-SR 400mg Tablet as it causes drowsiness.

The long-term use of Quticool-SR 400mg Tablet may cause potential side effects such as tardive dyskinesia (uncontrolled movements of arms and legs), increased blood sugar, vision impairment, and weight gain. However, if the benefits outweigh the risks, your doctor prescribes Quticool-SR 400mg Tablet for a prolonged period.

Quticool-SR 400mg Tablet is not recommended for use in children and adolescents under the age of 18 years. In children, it may cause potential side effects such as swelling of breasts in boys and girls, irregular periods and weight gain.

Drug-Drug Interactions Checker List

  • CITALOPRAM
  • ESCITALOPRAM
  • BUPROPION
  • ACETAMINOPHEN
  • HYDROCODONE
  • TRAMADOL

Special Advise

  • Quticool-SR 400mg Tablet may increase blood sugar levels even if you don't have diabetes, especially in patients with schizophrenia. So, it is recommended to immediately inform your doctor if you have symptoms such as increased thirst, frequent urination, fatigue or increased appetite.
  • If you are having a urine drug screen (an analysis to determine the presence of illegal drugs or drugs that are mostly abused, such as methadone or tricyclic antidepressants in the blood), the test results may show positive when certain test methods are used. A more specific test may be required in such cases.

Disease/Condition Glossary

Schizophrenia: Schizophrenia (psychosis) is a mental illness in which the processing of brain information is affected. Symptoms include hallucinations (seeing or hearing unreal things), delusions (false beliefs) and become withdrawal from society. They lose the ability to differentiate reality from false beliefs.

Bipolar disorder: Bipolar disorder or manic depression: Patients with bipolar disorders have mood swings ranging from manic episodes of heightened excitement to severe depression. Bipolar disorder may occur due to genetic factors, alcohol or drug abuse and mental trauma.

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