Rectol 250 mg Suppository 5's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Veda Maddala , M Pharmacy

Rectol 250 mg Suppository belongs to the group of analgesics (pain killers)

Prescription drug

MRP ₹72

(Inclusive of all Taxes)

₹10.8 Cashback (15%)

Provide Delivery Location

Non returnable*

Know More

COD available

Online payment accepted

Prescription drug

Whats That

About Rectol 250 mg Suppository

Rectol 250 mg Suppository belongs to the group of analgesics (pain killers), and antipyretics (fever-reducing agents) used to treat mild to moderate pain and fever in adults and children weighing at least 7kgs. Pain and fever are caused by the activation of pain receptors due to the release of certain natural chemicals in the body like prostaglandins.

Rectol 250 mg Suppository contains 'Paracetamol' which prevents the release of chemical messengers (prostaglandins) that cause pain and inflammation. Thus, relieves pain. Rectol 250 mg Suppository also acts as an antipyretic agent by affecting the chemical messengers in the brain that regulate body temperature. Thereby, reduces fever.

Your doctor will decide the dose and duration of Rectol 250 mg Suppository based on your condition. In some cases, Rectol 250 mg Suppository may cause side effects like rash, soreness in or around the rectum/anus, and itching. Most of these side effects do not necessitate medical attention and will resolve gradually over time. However, if the side effects persist or worsen, please consult a doctor.

Do not take Rectol 250 mg Suppository if you are allergic to any of its components. Inform your doctor if you have kidney or liver problems, alcoholism, infections or any other medical conditions. Consult your doctor if you are pregnant or breastfeeding. Do not exceed the recommended dosage as an overdose may be injurious to the liver. Do not swallow Rectol 250 mg Suppository; it is for anal administration only.

Uses of Rectol 250 mg Suppository

Pain relief, Fever

Directions for Use

Use Rectol 250 mg Suppository exactly as advised by the doctor. The suppository should be inserted into the rectum (back passage) by removing the plastic wrapper. Wash your hands before and after inserting the suppository.

Medicinal Benefits

Rectol 250 mg Suppository belongs to the group of analgesics (pain killers), and antipyretics (fever-reducing agents) used to treat mild to moderate pain and fever in adults and children weighing at least 7kgs. Rectol 250 mg Suppository prevents the release of chemical messengers (prostaglandin) that cause pain and inflammation. Thus, relieves pain. Rectol 250 mg Suppository also acts as an antipyretic agent by affecting the chemical messengers in the brain that regulate body temperature. Thereby, reduces fever.

Storage

Keep Rectol 250 mg Suppository out of reach and sight of children.

Side effects of Rectol 250 mg Suppository

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Increased Aspartate Aminotransferase (AST) In Blood

Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
Reduced alcohol intake can enhance liver enzyme function.
Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
Liver function tests regularly can help manage increased levels of AST.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Anemia

Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
Consume vitamin C-rich foods as they aid iron absorption.
Limit tea, cocoa, and coffee as these can slow iron absorption.
Exercise regularly; however, do not overdo it.

Rash

Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
Protect your skin from extreme heat and try to apply wet compresses.
Soak in the cool bath, which gives a soothing impact to the affected area.

Shortness Of Breath

Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):

Tell your doctor immediately if you experience shortness of breath after taking medication.
Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Drug Warnings

Do not take Rectol 250 mg Suppository if you are allergic to any of its components, have severe liver problems or if the child weighs below 7kgs. Inform your doctor if you have kidney or liver problems, inherited metabolic disease, alcoholism, infections or any other medical conditions. Consult your doctor if you are pregnant or breastfeeding. Do not exceed the recommended dosage as an overdose may be injurious to the liver. Do not swallow Rectol 250 mg Suppository; it is for anal administration only.

Drug-Drug Interactions

ParacetamolOxazepam

Severe

ParacetamolValdecoxib

Severe

Drug-Drug Interactions

Login/Sign Up

ParacetamolOxazepam

Severe

How does the drug interact with Rectol 250 mg Suppository:
Co-administration of Rectol 250 mg Suppository may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Rectol 250 mg Suppository, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

ParacetamolValdecoxib

Severe

How does the drug interact with Rectol 250 mg Suppository:
Co-administration of Rectol 250 mg Suppository and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Rectol 250 mg Suppository and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.

ParacetamolLomitapide

Severe

How does the drug interact with Rectol 250 mg Suppository:
Co-administration of Lomitapide and Rectol 250 mg Suppository may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Rectol 250 mg Suppository and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

ParacetamolKetamine

Severe

How does the drug interact with Rectol 250 mg Suppository:
Co-administration of ketamine and Rectol 250 mg Suppository may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Rectol 250 mg Suppository together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

ParacetamolTeriflunomide

Severe

How does the drug interact with Rectol 250 mg Suppository:
Co-administration of Teriflunomide with Rectol 250 mg Suppository may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Rectol 250 mg Suppository with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

ParacetamolLeflunomide

Severe

How does the drug interact with Rectol 250 mg Suppository:
Co-administration of Rectol 250 mg Suppository and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Rectol 250 mg Suppository and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

ParacetamolKetoconazole

Severe

How does the drug interact with Rectol 250 mg Suppository:
Co-administration of Rectol 250 mg Suppository and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Rectol 250 mg Suppository and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.

ParacetamolMipomersen

Severe

How does the drug interact with Rectol 250 mg Suppository:
Co-administration of Mipomersen with Rectol 250 mg Suppository may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Rectol 250 mg Suppository and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

Rest well, and get plenty of sleep.
Stay hydrated; drink plenty of water.
Mild exercises such as jogging and walking are helpful for muscle stretching.
To avoid developing pressure sores, change your position at least every two hours.
Hot or cold therapy can help treat pain. Apply an ice pack or hot pack on the muscle for 15-20minutes.

Side Effects of Rectol 250 mg Suppository

Rash
Itching
Soreness in or around the rectum/anus

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Rectol 250 mg Suppository Substitute

Metacin Suppositories 5's

by AYUR

₹2.52per tablet

Anamol 250 mg Suppositories 5's

by Others

₹7.38per tablet

Junimol RDS 250mg Suppository

by Others

₹7.94per tablet

Medipm 250 mg Suppositories 5's

by Others

₹16.00per tablet

Supposits P-250 Suppositories 2x5's

by Others

₹16.90per tablet

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:44 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

PARACETAMOL-250MGMental and behavioural disorders due to use of alcohol

Severe

PARACETAMOL-250MGHepatic failure, not elsewhere classified

Severe

Drug-Diseases Interactions

Login/Sign Up

PARACETAMOL-250MGMental and behavioural disorders due to use of alcohol

Severe

How does the disease interact with Rectol 250 mg Suppository:
Chronic alcoholics may have a higher risk of hepatotoxicity when using Rectol 250 mg Suppository. Patients using Rectol 250 mg Suppository may cause severe liver damage, including acute liver failure that required a liver transplant and resulted in death.

How to manage the interaction:
Rectol 250 mg Suppository should be used with caution in patients who consume three or more alcoholic drinks a day. Avoid alcohol consumption while taking Rectol 250 mg Suppository. If you have nausea, vomiting, fever, rash, anorexia (eating disorder), over-tiredness, upper right stomach pain, dark urine, and jaundice, contact your doctor as these may be signs and symptoms of liver injury.

PARACETAMOL-250MGHepatic failure, not elsewhere classified

Severe

How does the disease interact with Rectol 250 mg Suppository:
The liver predominantly converts Rectol 250 mg Suppository to inactive forms. Patients with hepatic impairment may be more prone to toxicity because their minor metabolic pathways are more active.

How to manage the interaction:
Rectol 250 mg Suppository should be used with caution in patients with kidney insufficiency. Also, it is recommended to avoid drinking alcohol while taking Rectol 250 mg Suppository.

FAQs

How does Rectol 250 mg Suppository relieve pain?

Rectol 250 mg Suppository prevents the release of chemical messengers (prostaglandins) that cause pain and inflammation. Thus, relieves pain.

Does Rectol 250 mg Suppository treat fever?

Rectol 250 mg Suppository acts as an antipyretic agent by affecting the chemical messengers in the brain that regulate body temperature. Thereby, reduces fever.

Can I take Rectol 250 mg Suppository with warfarin?

Consult your doctor before taking Rectol 250 mg Suppository with warfarin or blood thinners as taking them together may increase the risk of bleeding.

Is it safe to use Rectol 250 mg Suppository for longer durations?

Avoid using Rectol 250 mg Suppository for longer durations as it may cause headache. Also, do not exceed the recommended dosage as an overdose may be injurious to the liver.

Can I take Rectol 250 mg Suppository with zidovudine?

Rectol 250 mg Suppository when taken with zidovudine (anti-viral medication) might lower the white blood cell count. Therefore, consult your doctor before taking Rectol 250 mg Suppository with other medicines.

Drug-Drug Interactions Checker List

WARFARIN
ZIDOVUDINE
PROBENECID
CHLORAMPHENICOL
CHOLESTYRAMINE
METOCLOPRAMIDE
DOMPERIDONE

Disease/Condition Glossary

Pain: It is a term used to describe any unpleasant feeling or discomfort. It occurs due to nerve damage (in cases of backache, toothache, or muscle pain) or persistent stimulation (in headaches or migraine). Pain may vary from mild to severe, depending on the underlying condition.

Fever: When the body's temperature goes above 100.4°F (38°C), it is called fever or pyrexia. It is an abnormal increase in body temperature from normal (98.6°F) due to infection, chemotherapy or various disease conditions.