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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

METOCLOPRAMIDE-5MG

Manufacturer/Marketer :

Oaknet Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Reglan Syrup

Reglan Syrup belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, and which might occur after migraine. Additionally, Reglan Syrup is also used to treat gastro-oesophageal reflux disease (GERD), diabetic gastroparesis (delayed gastric emptying in people with diabetes), heartburn, ulcers and sores in the oesophagus.

Reglan Syrup contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

In some cases, Reglan Syrup may cause common side-effects such as restlessness, fatigue, drowsiness, diarrhoea, weakness, and lassitude (lack of energy). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not take Reglan Syrup for more than 3 months as it might increase the risk of tardive dyskinesia (movement disorder). Consult your doctor before taking Reglan Syrup if you are pregnant or breastfeeding. Reglan Syrup may cause drowsiness and dizziness, so avoid driving until you know how Reglan Syrup affects you. Avoid consuming alcohol along with Reglan Syrup as it could lead to increased drowsiness. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Reglan Syrup

Nausea, vomiting, gastroesophageal reflux disease (GERD), and diabetic gastroparesis (delayed gastric emptying in people with diabetes).

Directions for Use

Take Reglan Syrup 30 minutes before food, preferably at bedtime or as advised by the doctor. Tablet/Capsule: Swallow it as a whole with water; do not chew or break the tablet/capsule. Orally disintegrating tablet (ODT): Place the tablet on top of the tongue and allow it to dissolve. Do not handle the ODT with wet hands. Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the bottle well before each use.

Key Benefits

Reglan Syrup belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, and which might occur after migraine. Additionally, Reglan Syrup is also used to treat gastro-oesophageal reflux disease (GERD), diabetic gastroparesis (delayed gastric emptying in people with diabetes), heartburn, ulcers and sores in the oesophagus. Reglan Syrup contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also affects the dopamine receptor in the brain and gut, thereby helps in preventing nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight
Side effects of Reglan Syrup 60 ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

Drug Warnings

Do not take Reglan Syrup if you are allergic to any of its contents; if you have bleeding or obstruction in the stomach, tardive dyskinesia (movement disorder), pheochromocytoma (tumour in the adrenal glands), or epilepsy. Talk to your doctor before taking Reglan Syrup if you have heart problems, diabetes, depression, high blood pressure, breast cancer, seizures, liver or kidney problems, Parkinson’s disease, methaemoglobinaemia; if you are taking levodopa or if you have gastrointestinal surgery in the last 3-4days. Do not take Reglan Syrup for more than three months as it might increase the risk of tardive dyskinesia; the risk increases if you are older, especially if you are an older woman or if you have diabetes. Consult your doctor immediately if you cannot stop or control movements like shaking your arms and legs, blinking and moving your eyes, sticking out the tongue, frowning, lip-smacking, chewing, or puckering up the mouth.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Reglan Syrup 60 ml:
The combination of Lurasidone and Reglan Syrup 60 ml may result in significantly increased Lurasidone blood levels. This may raise the possibility of undesirable consequences such as Parkinson's disease. (It is a neurological condition that causes uncontrollable movements)and Tardive dyskinesia (uncontrollable movements, particularly of the lower face).

How to manage the interaction:
Lurasidone and Reglan Syrup 60 ml is not recommended, as they may interact, but can be used if a doctor prescribes them. Consult a doctor if you have muscle spasms, or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning, tongue thrusting, teeth clenching, jaw twitching, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without visiting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Co-administration of Reglan Syrup 60 ml with Aripiprazole can increase the risk of side effects.

How to manage the interaction:
Taking Aripiprazole with Reglan Syrup 60 ml is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Coadministration of Reglan Syrup 60 ml and prochlorperazine can increase the risk of side effects.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Prochlorperazine together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Co-administration of Reglan Syrup 60 ml with Clozapine can increase the risk of side effects.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Clozapine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Co-administration of Reglan Syrup 60 ml with Risperidone can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Risperidone with Reglan Syrup 60 ml is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking, jitteriness, restlessness, pacing, and foot tapping contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Reglan Syrup 60 ml:
Coadministration of Reglan Syrup 60 ml with Venlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Venlafaxine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Co-administration of Reglan Syrup 60 ml with Trifluoperazine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Trifluoperazine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping., contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Coadministration of Reglan Syrup 60 ml with Trazodone can rarely increase serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Trazodone is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any symptoms like dizziness, fever, excessive sweating, shivering, blurred vision, muscle stiffness, stomach cramps, nausea, vomiting, or diarrhoea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Coadministration of Reglan Syrup 60 ml with quetiapine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Quetiapine is generally avoided as it can possibly result in an interaction. They can be taken together if advised by your doctor. However, contact a doctor if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Co-administration of Reglan Syrup 60 ml with Cariprazine can increase the risk of side effects.

How to manage the interaction:
Taking Cariprazine with Reglan Syrup 60 ml is generally avoided, but can be taken together if prescribed by a doctor. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Drink fluids to stay hydrated.
  • Avoid solid foods until vomiting stops.
  • Avoid foods that might cause stomach upset.
  • Take ample rest. Avoid any activity immediately after eating.
  • Consume plain, light foods such as bread and biscuits.
  • Avoid food with strong flavours and fried food.
  • Ginger tea might help in proper digestion.

Side Effects of Reglan Syrup

  • Restlessness
  • Fatigue
  • Drowsiness
  • Diarrhoea
  • Weakness
  • Lassitude (lack of energy)

Habit Forming

No

Therapeutic Class

[ANTIEMETICS, GASTROPROKINETIC AGENTS]

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • ASPIRIN
  • ACETAMINOPHEN
  • DULOXETINE
  • DIPHENHYDRAMINE
  • ALPRAZOLAM
  • PREGABALIN
  • LEVODOPA

Special Advise

Your doctor may advise you to regularly get blood tests done to check your blood pigment levels. If Methaemoglobinaemia is observed, treatment with Reglan Syrup should be stopped immediately and permanently. Methaemoglobinaemia is a blood condition in which the haemoglobin iron is in the oxidized state and cannot reversibly bind to oxygen.

Disease/Condition Glossary

Nausea/Vomiting: Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the contents of the stomach through the mouth. Nausea and vomiting may occur separately or together. The common causes include motion sickness, emotional stress, indigestion, food poisoning, high fever or overeating. Nausea/vomiting might also occur as an unpleasant effect of therapy, such as chemotherapy and radiation therapy. 

Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.

Diabetic gastroparesis: Diabetic gastroparesis is delayed gastric emptying in people with diabetes. Gastroparesis, also called delayed gastric emptying is a condition that occurs when the stomach takes too long to empty the food into the intestine. Symptoms include nausea, vomiting, indigestion, loss of appetite, bloating and heartburn.

Have a query?

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Alcohol

Safe if prescribed

Avoid consumption of alcohol while taking Reglan Syrup as it may make some side effects worse such as increased sleepiness and drowsiness.

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Pregnancy

Consult your doctor

Consult your doctor before taking Reglan Syrup if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Reglan Syrup if you are breastfeeding.

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Driving

Safe if prescribed

Reglan Syrup may cause dizziness, drowsiness and fatigue. Do not drive or operate machinery until you know how Reglan Syrup affects you.

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Liver

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Reglan Syrup if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Reglan Syrup if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Metoclopramide tablets are not recommended for children due to the risk of tardive dyskinesia, extrapyramidal symptoms as well as risk of methemoglobinemia in neonates. Metoclopramide drops should be given to children only if prescribed by the doctor.

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