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Written By aquibnaseer ,
Reviewed By Sunny S , MBBS
Non returnable*
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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Resochin DS Tablet 5's

Resochin DS Tablet 5's belongs to the class of medications called 'quinoline' primarily used to treat malaria. Resochin DS Tablet 5's gives a degree of protection (prophylaxis) against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Resochin DS Tablet 5's is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). 

Resochin DS Tablet 5's contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Resochin DS Tablet 5's prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

Resochin DS Tablet 5's should be taken as prescribed by your doctor. The dose of Resochin DS Tablet 5's can vary depending upon your condition and the severity of the infection. The common side effects of Resochin DS Tablet 5's include vomiting, nausea, hair loss and itchy skin. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting Resochin DS Tablet 5's, please inform your doctor if you are allergic to chloroquine or have kidney or liver problems. Do not take Resochin DS Tablet 5's on your own. Resochin DS Tablet 5's is safe to use during pregnancy and breastfeeding. Prolonged use of Resochin DS Tablet 5's may have a severe risk on the heart and retina of the eyes leading to pounding heartbeats and permanent vision problems. 

Uses of Resochin DS Tablet 5's

Malaria, Intestinal amoebiasis, Rheumatoid arthritis

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup/Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Resochin DS Tablet 5's falls into a group of medicines known as antimalarials, indicated for treating or preventing malaria. Resochin DS Tablet 5's contains chloroquine, which belongs to quinoline. It works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism. Resochin DS Tablet 5's is also indicated for the treatment of rheumatoid arthritis and autoimmune diseases like lupus and intestinal infection caused by amoeba (amoebiasis).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Resochin DS Tablet 5's

  • Abnormal heart rhythm
  • Stomach pain
  • Nausea (being sick)
  • Diarrhoea
  • Loss of appetite
  • Headache
  • Skin rash
  • Liver problems

Drug Warnings

Resochin DS Tablet 5's does not respond well against all malaria strains, so consult with your doctor if you do not respond well to Resochin DS Tablet 5's. This medicine can affect heart health, especially if a person is taking medications, including the antibiotic azithromycin and anticancer like tamoxifen. An individual must consult with the doctor if they are noticing fast or pounding heartbeats and sudden dizziness. This medicine cannot be used for a long duration as it may cause irreversible damage to the eye that could lead to vision problems. Resochin DS Tablet 5's cannot be used in persons who have heart disease, heart rhythm disorder, diabetes, a stomach disorder, an allergy to quinine, liver or kidney disease, psoriasis, alcoholism, porphyria (a genetic enzyme disorder that affects the skin or nervous system), a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Consult with your doctor if you are pregnant or breastfeeding as this medicine could only be used if prescribed by the doctor. 

Drug-Drug Interactions

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ChloroquineZiprasidone
Critical
ChloroquineSaquinavir
Critical

Drug-Drug Interactions

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ChloroquineZiprasidone
Critical
How does the drug interact with Resochin DS Tablet:
Taking Resochin DS Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Resochin DS Tablet with Ziprasidone is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, confusion, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
ChloroquineSaquinavir
Critical
How does the drug interact with Resochin DS Tablet:
Using saquinavir together with Resochin DS Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Resochin DS Tablet with Saquinavir is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineAgalsidase beta
Critical
How does the drug interact with Resochin DS Tablet:
Using Resochin DS Tablet with Agalsidase beta can reduce the effectiveness of agalsidase beta.

How to manage the interaction:
Taking Agalsidase beta with Resochin DS Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquineTelavancin
Critical
How does the drug interact with Resochin DS Tablet:
Using Resochin DS Tablet together with telavancin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Telavancin with Resochin DS Tablet is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineLevacetylmethadol
Critical
How does the drug interact with Resochin DS Tablet:
Using Levacetylmethadol together with Resochin DS Tablet can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Resochin DS Tablet with Levacetylmethadol is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquinePimozide
Critical
How does the drug interact with Resochin DS Tablet:
When Pimozide and Resochin DS Tablet are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Resochin DS Tablet with Pimozide is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineBepridil
Critical
How does the drug interact with Resochin DS Tablet:
Using Resochin DS Tablet together with bepridil can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Resochin DS Tablet with Bepridil is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChloroquineAuranofin
Critical
How does the drug interact with Resochin DS Tablet:
Taking Auranofin with Resochin DS Tablet can increase the risk of blood disorders and other severe side effects

How to manage the interaction:
Taking Auranofin with Resochin DS Tablet is not recommended, as it may lead to an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChloroquineAgalsidase alfa
Critical
How does the drug interact with Resochin DS Tablet:
When Agalsidase alfa is used with Resochin DS Tablet, it may decrease the effectiveness of the Agalsidase alfa.

How to manage the interaction:
Taking Agalsidase alfa with Resochin DS Tablet is not recommended, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquinePazopanib
Critical
How does the drug interact with Resochin DS Tablet:
Taking pazopanib with Resochin DS Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Pazopanib with Resochin DS Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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CHLOROQUINE-500MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CHLOROQUINE-500MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grape fruit products while using Resochin DS Tablet, can increase the risk of irregular heartbeat, which may result in side effects such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Avoid grape fruit and its products while taking Resochin DS Tablet.

Diet & Lifestyle Advise

  • Always take Resochin DS Tablet 5's with meals for reduced gastric irritation.
  • Adequate nutrition is the key for improvement in malaria induced weakness.
  • It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
  • Increase fluid and protein intake for malaria induced weight loss.
  • Proper rest and mosquito-free premises is important for the patient to recover.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Resochin DS Tablet 5's Substitute

Substitutes safety advice
  • Lariago-DS Tablet 5's

    by Others

    3.06per tablet
  • EMQUIN DS 500MG TABLET

    by Others

    1.42per tablet
  • LEOQUIN 500EC TABLET

    by Others

    2.66per tablet

Author Details

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Drug-Diseases Interactions

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CHLOROQUINE-500MGDisorders of porphyrin and bilirubin metabolism
Severe
CHLOROQUINE-500MGOther cardiac arrhythmias
Moderate

Drug-Diseases Interactions

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CHLOROQUINE-500MGDisorders of porphyrin and bilirubin metabolism
Severe
How does the disease interact with Resochin DS Tablet:
Porphyria: In porphyria the use of Resochin DS Tablet may aggravate this condition. Avoid Resochin DS Tablet use until it is required.

How to manage the interaction:
If the risks aren't expected to outweigh the possible advantages, Resochin DS Tablet shouldn't be utilized on these patients.
CHLOROQUINE-500MGOther cardiac arrhythmias
Moderate
How does the disease interact with Resochin DS Tablet:
Arrhythmias:Resochin DS Tablet has adverse effect like prolongation of QT interval, ventricular arrhythmias and torsades de pointes. Monitor ECG before initiation and during the therapy.

How to manage the interaction:
If you have sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat while taking these medications, whether they are taken together or separately, you should seek immediate assistance from a doctor. A close monitoring of ECG is required.
CHLOROQUINE-500MGEpilepsy
Moderate
How does the disease interact with Resochin DS Tablet:
Seizures: Resochin DS Tablet may cause epileptic seizures in susceptible patients. Administer Resochin DS Tablet in patients with history of epilepsy.

How to manage the interaction:
In those who are vulnerable, Resochin DS Tablet may result in epileptic fits. Patients who already have epileptic fits or have a low tolerance for seizures may be at greater risk.
CHLOROQUINE-500MGOther diseases of blood and blood-forming organs
Moderate
How does the disease interact with Resochin DS Tablet:
Bone marrow suppression: With the use of Resochin DS Tablet adverse effects such as neutropenia, agranulocytosis, aplastic anemia, and thrombocytopenia. In patients with preexisting bone marrow suppression use cautiously and monitor for complete blood count. Discontinue the Resochin DS Tablet if any serious blood disorder is suspected.

How to manage the interaction:
It is important to inform your doctor if you have prior conditions like bone marrow suppression, a complete blood picture is advised to be taken if you are on a long term therapy with Resochin DS Tablet. If you suspect any blood disorders, please inform it to your doctor immediately.
CHLOROQUINE-500MGOther hearing loss
Moderate
How does the disease interact with Resochin DS Tablet:
Ototoxicity: Rarely, Resochin DS Tablet was been associated with ototoxicity.The use of Resochin DS Tablet has been associated rarely with ototoxicity. With long-term, high-dose Resochin DS Tablet therapy which is irreversible nerve-type deafness may occur. In some patients with preexisting auditory damage, tinnitus, decrease in hearing may occur. Use with caution and discontinue therapy if new auditory defects occur or if hearing loss becomes worse.

How to manage the interaction:
If you any existing hearing damage, do not forget to inform it your doctor, so that a close monitoring can be done during the treatment with Resochin DS Tablet.
CHLOROQUINE-500MGPsoriasis
Moderate
How does the disease interact with Resochin DS Tablet:
In psoriasis patients, the Resochin DS Tablet use may exacerbate severe attack of psoriasis. Do not use Resochin DS Tablet unless the potential benefits vs risks outweighs.

How to manage the interaction:
It is important to tell your doctor if you have any existing skin conditions like psoriasis. Your doctor may prescribe the medication, if the benefits are more than the risks.
CHLOROQUINE-500MGMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Resochin DS Tablet:
myasthenia gravis Use of Resochin DS Tablet may exacerbate new onset of symptoms in patients with previously diagnosed myasthenia gravis. Use cautiously.

How to manage the interaction:
If you are suffering from myasthenia gravis, do not forget to tell it to your doctor. If you are taking Resochin DS Tablet and experiencing symptoms like muscle weakness or weakness of the arms and legs, drooping of upper eyelid, difficulty speaking, difficulty swallowing, double vision, tiredness, or shortness of breath please inform your doctor.

Drug-Drug Interactions Checker List

  • PHENYLBUTAZONE
  • NEOSTIGMINE
  • PYRIDOSTIGMINE
  • AMPICILLIN
  • CIMETIDINE
  • TAMOXIFEN

Special Advise

Do not take Resochin DS Tablet 5's if you have had a previous reaction to Resochin DS Tablet 5's, or if you have certain eye problems involving your retina. Tell your healthcare provider about any problems you may have with your eyes.

Disease/Condition Glossary

Malaria: It is a severe & fatal parasitic infection caused by a protozoan called Plasmodium. 4 types of parasites can infect humans with malaria: Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria. Female anopheles mosquito bites cause it. If bitten by an infected mosquito (the Anopheles mosquito), malaria parasites are injected into the blood. These parasites then migrate to the liver where they multiply via the bloodstream. A patient doesn't feel sick at this period because the parasites are in the liver. Then the parasites leave the liver and enter the red blood cells where the parasites are developing, and then the red blood cells burst, allowing them to transfer to another blood cell. The parasites release harmful chemicals into the bloodstream at this point, and the patient begins to feel ill. Malaria leads to periodic fever-chills, anaemia, kidney failure, and jaundice due to excessive red blood cell death due to plasmodium growth inside them.

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