apollo
0
Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition

ELTROMBOPAG-25MG

Manufacturer/Marketer

Novartis India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Revolade 25mg Tablet

Revolade 25mg Tablet belongs to the class of 'platelet-stimulating agents' primarily used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Revolade 25mg Tablet is also used to treat severe aplastic anaemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused due to hepatitis C virus. Severe aplastic anaemia is a condition in which the bone marrow doesn't make enough blood cells.

Revolade 25mg Tablet contains 'Eltrombopag' which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet's production. Revolade 25mg Tablet works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Revolade 25mg Tablet helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

Take Revolade 25mg Tablet as prescribed by your doctor. In some cases, Revolade 25mg Tablet can cause common side effects like nausea, diarrhoea, headache, muscle pain, tiredness, loss of appetite, fever, anaemia (lack of blood cells), cough and tingling numbness. These side effects are not familiar to everyone who take Revolade 25mg Tablet and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you have any allergic reactions to Revolade 25mg Tablet or any other medicines, before starting Revolade 25mg Tablet. It is essential to inform your doctor if you have any heart, kidney or liver problems, blood disorders, blood clotting problems and cataracts before starting Revolade 25mg Tablet. It is advised to consult the doctor if you are pregnant or planning to conceive. Revolade 25mg Tablet is not indicated for use in breastfeeding since it passes into the breast milk. Revolade 25mg Tablet may make you dizzy, hence drive or operate machinery only when you are mentally alert. 

Uses of Revolade 25mg Tablet

Low platelet count and Severe aplastic anaemia (SAA).

Directions for Use

Tablet: Swallow it as a whole with a glass of water. Take it on an empty stomach as prescribed by the doctor. Do not crush, chew or break it. Oral suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.Powder: Mix the powder with the prescribed amount of water. Take it with or without food with an oral syringe in the dose and duration prescribed by the doctor.

Medicinal Benefits

Revolade 25mg Tablet contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA) in adults. Revolade 25mg Tablet works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets. The increase in these bone marrow cells stimulates the production of platelets. Thus Revolade 25mg Tablet prevents bleeding episodes by increasing the number of platelets in the blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Revolade 25mg Tablet

  • Nausea
  • Diarrhoea
  • Headache
  • Muscle pain
  • Tiredness
  • Loss of appetite
  • Fever
  • Anaemia (lack of blood cells)
  • Cough
  • Tingling or numbness 

Drug Warnings

If you are known to be allergic to Revolade 25mg Tablet or other medicines, please inform your doctor in advance. Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Revolade 25mg Tablet. Take Revolade 25mg Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Revolade 25mg Tablet. Revolade 25mg Tablet is not recommended during pregnancy since it may have harmful effects on the foetus. Consult your doctor before using Revolade 25mg Tablet if you are a breastfeeding mother. Do not drive or operate machinery since Revolade 25mg Tablet may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive. Avoid or limit alcohol consumption with Revolade 25mg Tablet as it may affect the efficacy of Revolade 25mg Tablet. Revolade 25mg Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA. 

Drug-Drug Interactions

verifiedApollotooltip
EltrombopagFerric maltol
Critical
EltrombopagMagnesium citrate
Critical

Drug-Drug Interactions

Login/Sign Up

EltrombopagFerric maltol
Critical
How does the drug interact with Revolade 25mg Tablet:
Ferric maltol can make Revolade 25mg Tablet less effective by reducing its absorption and lowering its concentration in the blood. This can lead to poor treatment outcomes.

How to manage the interaction:
Taking Ferric maltol with Revolade 25mg Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Revolade 25mg Tablet on an empty stomach at least 2 hours before or 4 hours after ferric maltol. Do not discontinue any medication without consulting a doctor.
EltrombopagMagnesium citrate
Critical
How does the drug interact with Revolade 25mg Tablet:
Taking magnesium citrate with Revolade 25mg Tablet can make it less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Taking Magnesium citrate with Revolade 25mg Tablet is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. You should take Revolade 25mg Tablet on an empty stomach at least 2 hours before or 4 hours after magnesium citrate. Do not discontinue any medication without consulting a doctor.
EltrombopagCalcium chloride
Critical
How does the drug interact with Revolade 25mg Tablet:
When Revolade 25mg Tablet is mixed with Calcium chloride, the amount of Revolade 25mg Tablet in the blood can decrease. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Revolade 25mg Tablet with calcium chloride is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EltrombopagMagnesium oxide
Critical
How does the drug interact with Revolade 25mg Tablet:
Coadministration of Magnesium oxide with Revolade 25mg Tablet can impair the absorption of Revolade 25mg Tablet which leads to increased levels in the blood. This can increase the risk and severity of side effects.

How to manage the interaction:
Taking Magnesium oxide with Revolade 25mg Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EltrombopagAluminium hydroxide
Critical
How does the drug interact with Revolade 25mg Tablet:
Coadministration of Revolade 25mg Tablet and aluminum hydroxide may interfere with the absorption of Revolade 25mg Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Revolade 25mg Tablet with aluminum hydroxide is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EltrombopagFerrous gluconate
Critical
How does the drug interact with Revolade 25mg Tablet:
Ferrous gluconate can make Revolade 25mg Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Revolade 25mg Tablet with Ferrous gluconate is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Revolade 25mg Tablet on an empty stomach at least 2 hours before or 4 hours after ferrous gluconate. Do not discontinue any medication without consulting a doctor.
EltrombopagLenalidomide
Severe
How does the drug interact with Revolade 25mg Tablet:
Coadministration of Revolade 25mg Tablet with lenalidomide can increase the risk or severity of blood clots.

How to manage the interaction:
Although there is an interaction between lenalidomide and Revolade 25mg Tablet, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EltrombopagPeginterferon alfa-2a
Severe
How does the drug interact with Revolade 25mg Tablet:
Combining Revolade 25mg Tablet with Peginterferon alfa-2a can lower the metabolism of Revolade 25mg Tablet. This can increase the risk or severity of liver damage.

How to manage the interaction:
There may be a possibility of interaction between Revolade 25mg Tablet and Peginterferon alfa-2a, but it can be taken if prescribed by a doctor. If you have any of these symptoms like confusion, changes in consciousness, harmful substances in the blood, bleeding from enlarged veins, bleeding, infection of the abdominal wall, complications, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, feeling tired, feeling sick, throwing up, bleeding, pain, dark urine, it's important to call a doctor right away. Do not discontinue any medications without consulting a doctor.
EltrombopagInterferon alfa-2a
Severe
How does the drug interact with Revolade 25mg Tablet:
Coadministration of Revolade 25mg Tablet with Interferon alfa-2a can increase the risk or severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Revolade 25mg Tablet and Interferon alfa-2a, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
EltrombopagInterferon alfa-n1
Severe
How does the drug interact with Revolade 25mg Tablet:
Coadministration of Revolade 25mg Tablet and Interferon alfa-n1 can increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Revolade 25mg Tablet and Interferon alfa-n1 together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Eat natural and healthy foods by cutting down on fatty and sodium processed foods.
  • Exercise regularly to maintain good health.
  • Avoid smoking and alcohol intake.
  • Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
  • High protein diet such as lean meat, chicken, crab, turkey, beef and fish can help increase the platelet count.
  • Eating Papaya is the best natural remedy to increase your platelet count, you can also use papaya leave's mixture.
  • Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
  • Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit and broccoli can also boost your platelet count.

Habit Forming

No

Therapeutic Class

PLATELET STIMULATING AGENTS

Revolade 25mg Tablet Substitute

Substitutes safety advice
  • Eltromag 25 Tablet 7's

    by Others

    57.21per tablet
  • Rebopag 25 mg Tablet 7's

    by Others

    192.86per tablet
  • Platify 25 Tablet 10's

    by Others

    144.00per tablet
  • Trombonat 25 Tablet 7's

    by Others

    180.00per tablet
  • Elromo 25 Tablet 7's

    by Others

    168.81per tablet

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

FAQs

Revolade 25mg Tablet contains Eltrombopag that stimulates platelet's production (helps in clotting) from megakaryocytes (bone marrow cells). Thus Revolade 25mg Tablet lowers the risk of bleeding episodes in diseases like immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA).

Do not stop using Revolade 25mg Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.

Revolade 25mg Tablet should be used with caution and only under doctor's supervision in cases of any allergic reactions, blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases.

Revolade 25mg Tablet decreases the risk of bleeding by increasing the platelet count in your body. However, you are advised to stay away from activities that may increase your risk of bleeding like contact sports and using sharp objects like razors and nail cutters.

It is advised to take Revolade 25mg Tablet on an empty stomach. Please take Revolade 25mg Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Revolade 25mg Tablet.

Drug-Drug Interactions Checker List

  • METHOTREXATE
  • TOPOTECAN
  • CICLOSPORIN
  • AZATHIOPRINE
  • LOPINAVIR
  • RITONAVIR
  • DANAZOL
  • IRON
  • CALCIUM
  • ZINC+ZINC GLUCONATE

Special Advise

  • Keep a check on your daily blood pressure and blood sugar levels and if you notice any fluctuations, please consult a doctor.
  • Since Revolade 25mg Tablet affects liver enzymes, your doctor may suggest liver function tests to check your aspartate aminotransferase (AST), alanine aminotransferase (ALT) and bilirubin levels before starting treatment and every two weeks after the treatment with Revolade 25mg Tablet.
  • Revolade 25mg Tablet may also interfere with creatinine and bilirubin lab tests, hence, please inform your doctor and laboratory staff in advance.

Disease/Condition Glossary

Immune (idiopathic) thrombocytopenic purpura (ITP): It is an immune condition associated with low levels of platelets, and the blood doesn't clot normally. It occurs when the immune system mistakenly attacks its own platelets. ITP also occurs in children, followed by a viral infection. Symptoms of ITP may include easy bruising, bleeding from gums and nose, blood in urine and stools, heavy menstrual flow and pinpoint-sized reddish-purple spots on the lower legs.

Hepatitis C: It is an infection and inflammation of the liver caused due to hepatitis C virus. This virus can cause both acute and chronic hepatitis. Acute hepatitis C is a short term illness that may range for six months. Chronic hepatitis C is a long-lasting disease that may lead to other severe liver cancer problems or cirrhosis (inflammation of the liver). Symptoms of hepatitis C include fatigue, nausea, loss of appetite and yellowing of the eyes and skin.

Severe aplastic anaemia (SAA): Aplastic anaemia is also called bone marrow aplasia. It is a condition in which the bone marrow doesn't make enough blood cells. SAA is commonly caused due to the damage of bone marrow. This damage can be a congenital disability or may occur because of radiation, chemotherapy, toxic chemicals, certain drugs and infections. Symptoms of SAA include fatigue, frequent infections, rapid heart rate and bleeding. 

whatsapp Floating Button