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Reviewed By Sunny S , MBBS
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Composition :

ROSUVASTATIN-40MG

Manufacturer/Marketer :

Lenin Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Roznen-40 Tablet

Roznen-40 Tablet belongs to the class of medicines known as statins, which reduces bad cholesterol (low-density lipoprotein-LDL) and glyceride level, thereby reducing the risk of heart attack and stroke in the future. High cholesterol, known as hyperlipidemia or dyslipidemia, occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high cholesterol level in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases like stroke and heart attack. 

Roznen-40 Tablet works by blocking liver enzymes, causing the liver to make less cholesterol. Roznen-40 Tablet increases the uptake and breakdown by the liver of cholesterol already in the blood. Thus, Roznen-40 Tablet lowers the levels of lipids known as cholesterol and triglycerides in the blood when lifestyle changes (like a low-fat diet) on their own have failed. Roznen-40 Tablet reduces the ‘bad’ cholesterol and increases the ‘good’ cholesterol by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood.

The possible side effects of Roznen-40 Tablet may include myalgia (muscle pain), asthenia (lack of energy), nausea, headache, abdominal pain, muscle pain, weakness, and daytime drowsiness. Most of these side effects of Roznen-40 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. It is important to have your lipid profile checked regularly.

This medicine is only one part of a treatment program that should include a healthy low-fat diet, regular exercise, smoking cessation, moderation of alcohol intake and weight reduction. You can normally eat while taking this medicine but avoid high-fat foods. Before starting the dose of Roznen-40 Tablet , tell your doctor if you have kidney problems, are pregnant or breastfeeding, diabetes, severe lung disease, or musculoskeletal disorder (like myopathy and rhabdomyolysis). You should avoid taking Roznen-40 Tablet with immune system affecting medicine (cyclosporine) or anti-HIV medicines (lopinavir, ritonavir, or atazanavir) as it might have a serious effect.

Uses of Roznen-40 Tablet

Hyperlipidemia (high cholesterol), Prevention of heart attack, Prevention of stroke.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Sprinkle Capsule: The capsule should be consumed whole. Do not chew or crush. For patients who have trouble swallowing, open the capsule and sprinkle the contents over a small amount (tablespoon) of soft food (curd, honey, tomato ketchup, vanilla and chocolate flavour pudding) and consume it.

Medicinal Benefits

Roznen-40 Tablet lowers the risk of cardiovascular disease and coronary events like heart attack, stroke, and heart-related chest pain (angina). Roznen-40 Tablet is beneficial in patients who are at high risk of these events. It is also prescribed in children (aged eight years or more) suffering from familial hypercholesterolemia (a genetic disease resulting in high cholesterol) along with lipid-lowering pills and other dietary measures. Roznen-40 Tablet plays a vital role in slowing atherosclerosis progress (blocked artery walls of heart due to fat/lipid deposition leading to heart attack and stroke) in adult patients.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Roznen-40 Tablet

  • Myalgia (muscle pain)
  • Asthenia (lack of energy)
  • Nausea
  • Headache
  • Abdominal pain
  • Muscle pain
  • Weakness
  • Daytime drowsiness

Drug Warnings

A prolonged intake of Roznen-40 Tablet may cause muscular disorders like myopathy and rhabdomyolysis with kidney damage. A person taking excess alcohol and affected with liver disease should consult a doctor before its intake. Caution should be exercised if you are taking any blood thinner or anticoagulants like warfarin or coumarin. At least 2 hours gap should be maintained between intake of Roznen-40 Tablet and antacids like magnesium hydroxide and aluminium hydroxide. Increases in HbA1c and fasting glucose levels can be observed if a person regularly takes Roznen-40 Tablet . So you should tell the doctor before having these diabetes tests. Patients with proteinuria (protein in urine) or haematuria (blood in urine) should tell the doctor before taking the Roznen-40 Tablet , as it might require dose adjustment. It is recommended that you should have a liver enzyme test regularly if you are regularly taking Roznen-40 Tablet .

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products. 
  • Quitting smoking is the best strategy to lower the risk of heart disease. 
  • Avoid chronic stress. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques. 
  • Including heart-healthy omega-3 fatty acid-containing food drinks in your daily diet.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

Roznen-40 Tablet Substitute

Substitutes safety advice
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  • Crestor 40 mg Tablet 15's

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  • Novastat 40 mg Tablet 15's

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  • Roseday 40 Tablet 10's

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FAQs

Roznen-40 Tablet works by blocking liver enzymes, causing the liver to make less cholesterol. So, Roznen-40 Tablet increases the uptake and breakdown by the liver of cholesterol already in the blood. Thus, Roznen-40 Tablet lowers the levels of lipids known as cholesterol and triglycerides in the blood when lifestyle changes (like a low-fat diet) on their own have failed.

No, Roznen-40 Tablet should not be stopped even if you feel better as it lead to worsening of your condition. Please consult your doctor if you feel better and do as advised.

Roznen-40 Tablet can cause liver damage in very rare cases, specially when alcohol is consumed along with Roznen-40 Tablet . Caution should be taken in patients who have any underlining liver problem or history of any liver impairment and also inform your doctor before taking Roznen-40 Tablet so that dose is adjusted accordingly.

It's unlikely that Roznen-40 Tablet affects fertility in men or women. However there's not enough evidence to say for certain. Roznen-40 Tablet should be avoided if your pregnant or planning for pregnancy. For best advise, consult your doctor.

Yes, taking Roznen-40 Tablet can cause muscle aches or pains especially if you feel unwell or have a fever. Also please tell your doctor if you have a muscle weakness that is constant.

Yes, Roznen-40 Tablet can be taken at night or any other time with or without food. It is better to take it at fixed time.

Yes, Roznen-40 Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Roznen-40 Tablet . In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.

Before starting dose of Roznen-40 Tablet tell your doctor if you have liver/kidney problems, under active thyroid (hypothyroidism), are pregnant or breastfeeding, diabetes, severe lung disease, blood in urine (haematuria) and protein in urine (proteinuria) or musculoskeletal disorder (like myopathy and rhabdomyolysis). You should avoid taking Roznen-40 Tablet with immune system affecting medicine (cyclosporine) or anti HIV medicines (lopinavir, ritonavir, or atazanavir) as it might have serious effect.

Usually, it is not safe to take Roznen-40 Tablet with fusidic acid as it may lead to muscle weakness, tenderness or pain. Please consult your doctor before taking Roznen-40 Tablet along with fusidic acid.

Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • WARFARIN
  • CLOPIDOGREL
  • GEMFIBROZIL
  • FENOFIBRATE
  • EZETIMIBE
  • ALUMINIUM HYDROXIDE
  • MAGNESIUM HYDROXIDE
  • ERYTHROMYCIN
  • FUSIDIC ACID
  • REGORAFENIB
  • RITONAVIR
  • LOPINAVIR
  • ATAZANAVIR
  • SIMEPREVIR
  • OMBITASVIR
  • PARITAPREVIR
  • DASABUVIR
  • VELPATASVIR
  • GRAZOPREVIR
  • ELBASVIR
  • GLECAPREVIR
  • PIBRENTASVIR

Special Advise

  • Your doctor may advise on regular monitoring of liver function tests to monitor the liver enzymes.

Disease/Condition Glossary

High cholesterol: There are two types of cholesterol found in our body, good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol from our body. On the other hand, excess of bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke. High cholesterol known as hyperlipidaemia or dyslipidaemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged that finally contributes to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol.

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