Rubuphine 10 mg Injection 1 ml belongs to the group of opioid analgesics used to relieve severe pain. It may also be used as an adjunct to balanced anaesthesia for pre/post-operative analgesia, during labour and delivery. Pain is defined as an unpleasant sensation produced in the body in response to external changes, stress, or trauma.

Rubuphine 10 mg Injection 1 ml contains 'Nalbuphine' that works by reducing the production of inflammatory substances (prostaglandins) and thus, relieves the body of swelling and subsequent pain. Rubuphine 10 mg Injection 1 ml also blocks pain-producing nerve transmitters, leading to a reduced sensation of pain and offering massive pain relief.

Rubuphine 10 mg Injection 1 ml will be administered by a qualified health care professional. Do not self-inject. Rubuphine 10 mg Injection 1 ml may cause certain common side effects such as drowsiness, dry mouth, nausea, vomiting, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

It is advisable to inform the doctor if you are allergic to any of the components of Rubuphine 10 mg Injection 1 ml. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding as Rubuphine 10 mg Injection 1 ml should be used with caution in these states. Rubuphine 10 mg Injection 1 ml may cause drowsiness, so avoid driving or operating machinery.

Rubuphine 10 mg Injection 1 ml is an analgesic that is used as a painkiller for short-term management of severe pain. Rubuphine 10 mg Injection 1 ml blocks pain signals, so the brain doesn't perceive the severity of pain, hence increasing the body's threshold for pain. Rubuphine 10 mg Injection 1 ml may also be used as an adjunct to balanced anaesthesia for pre/post-operative analgesia, during labour and delivery.

• Drowsiness
• Nausea
• Constipation
• Vomiting
• Dry mouth

Do not take Rubuphine 10 mg Injection 1 ml if you are allergic to any of the contents; if you have acute or severe asthma, respiratory depression, gastrointestinal obstruction, or paralytic ileus. Rubuphine 10 mg Injection 1 ml should not be taken with other opioid analgesics, CNS depressant drugs, or benzodiazepines as it might lead to life-threatening respiratory depression. Inform your doctor if you have asthma, COPD, adrenal insufficiency, severe hypotension, increased intracranial pressure, brain problems, head injury, gastrointestinal problems, seizures, kidney or liver problems. Avoid driving or operating machinery as Rubuphine 10 mg Injection 1 ml may impair your mental and physical ability. You are advised not to take alcohol with Rubuphine 10 mg Injection 1 ml as it might cause increased sedation and respiratory depression. Keep your doctor informed if you or anyone in your family have a history of substance abuse as Rubuphine 10 mg Injection 1 ml may cause addiction, abuse, and misuse.

Drug-Drug Interactions: Rubuphine 10 mg Injection 1 ml may interact with other opioid analgesics, CNS depressants, benzodiazepines, muscle relaxants, diuretics, anticholinergic drugs, and monoamine oxidase inhibitors.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have asthma, paralytic ileus, respiratory depression, COPD, adrenal insufficiency, severe hypotension, increased intracranial pressure, brain problems, head injury, gastrointestinal problems, seizures, depression, kidney or liver problems.

• Stay hydrated by drinking plenty of water.
• Invest in a balanced diet. Load up on lean meats, fruits, green leafy vegetables, nuts, oily fish etc. Limit your intake of sweets and sugars as these can worsen inflammation. 
• Cut back on alcohol as this can have an adverse effect on pain states as well as the quality of your sleep.
• Try meditation and deep breathing to reduce overall stress and pain. 
• Stop smoking as smoking is known to worsen pain conditions. 
• Engage in mild physical exercise daily and keep your body active.

Pain: Pain is a sensation that occurs in response to external injury, stress, infection and travels as an impulse through body cells, producing an unpleasant feeling and alerting the body to act. Pain relief in pharmacological terms is called analgesia. Various neurotransmitters and their equilibrium are instrumental in producing pain sensation.