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Manufacturer/Marketer :

Novo Nordisk India Pvt Ltd

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PARENTERAL

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About Ryzodeg 100IU/ml Flextouch Pen 3 ml

Ryzodeg 100IU/ml Flextouch Pen 3 ml belongs to the class of medications called ‘antidiabetics’ primarily used for the treatment of both type 1 and type 2 diabetes mellitus. It maintains blood sugar levels in adults and children. In Diabetes Mellitus Type 1, the body does not produce enough insulin to regulate blood sugar levels. On the other hand, in Diabetes Mellitus type 2, either the body stops producing enough insulin (a hormone that helps lower blood sugar levels), or there is resistance to insulin action. As a result, insulin is produced in large quantities, but it is not capable of operating on the body's organs.

Ryzodeg 100IU/ml Flextouch Pen 3 ml is a combination of two drugs, namely, Insulin Aspart and Insulin Degludec. Insulin aspart is a fast-acting or short-acting form of insulin that helps lower blood sugar levels after food intake. Insulin degludec is a long-acting form of insulin which begins working after 60 minutes and is a long-acting insulin preparation (lasts for more than 24 hours). Ryzodeg 100IU/ml Flextouch Pen 3 ml stimulates the recovery of sugar in muscle and fat cells and suppresses sugar production in the liver. Together, Ryzodeg 100IU/ml Flextouch Pen 3 ml confirm rapid and stable sugar control by helping reuptake of sugar in fat cells and muscle, and suppressing the creation of sugar in the liver.

Take Ryzodeg 100IU/ml Flextouch Pen 3 ml as prescribed by your doctor. You are advised to take Ryzodeg 100IU/ml Flextouch Pen 3 ml for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience rash, injection site allergic reaction, weight gain, oedema (tissue swelling or fluid overload), lipodystrophy (skin thickening or pits at the injection site), hypoglycemia (low blood glucose level), itching. Most of these side effects of Ryzodeg 100IU/ml Flextouch Pen 3 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Ryzodeg 100IU/ml Flextouch Pen 3 ml of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Ryzodeg 100IU/ml Flextouch Pen 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Ryzodeg 100IU/ml Flextouch Pen 3 ml, you should take a healthy diet, do regular exercise, and maintain weight as advised by your doctor. Ryzodeg 100IU/ml Flextouch Pen 3 ml is a cold chain medicine, and so it must be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might get lost. Do not store in the freezer of the fridge.

Uses of Ryzodeg 100IU/ml Flextouch Pen 3 ml

Type 1 diabetes mellitus, Type 2 diabetes mellitus

Directions for Use

Ryzodeg 100IU/ml Flextouch Pen 3 ml should be administered subcutaneously (in the upper thigh, abdomen, upper arm, or buttocks). If you are not trained to self-administer Ryzodeg 100IU/ml Flextouch Pen 3 ml, ask your healthcare professional to administer it.

Medicinal Benefits

Ryzodeg 100IU/ml Flextouch Pen 3 ml belongs to the class of medications called ‘antidiabetics’ primarily used for the treatment of both type 1 and type 2 diabetes mellitus. Ryzodeg 100IU/ml Flextouch Pen 3 ml is a combination of two drugs, namely, Insulin Aspart and Insulin Degludec. Ryzodeg 100IU/ml Flextouch Pen 3 ml contains insulin aspart, which is a fast-acting form of insulin that helps lower blood sugar levels after food intake. Ryzodeg 100IU/ml Flextouch Pen 3 ml contains insulin degludec, which is a prolonged action form of insulin. It typically begins working after 60 minutes and is a long-acting insulin preparation (lasts for more than 24 hours). Together, they confirm rapid and stable sugar control by helping reuptake sugar in fat and muscle, and cells and suppressing the creation of sugar in the liver. 

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Ryzodeg 100IU/ml Flextouch Pen 3 ml
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Rest well; get enough sleep. This helps the body fight infection.
  • Keep yourself hydrated by drinking enough water and other fluids.
  • Wash your hands often and avoid touching your eyes, mouth or nose.
  • Wear a mask whilst going out.
  • Warm steam or a hot shower may help with nose secretions.
  • Avoid contact with others to prevent contamination.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Apply pressure for 5-10 minutes to reduce bleeding.
  • Apply cold compresses or ice packs for 15-20 minutes, repeat every few hours.
  • Consult the doctor and use antihistamines if advised to minimise injection site reaction.
  • Use pain relief medication, like acetaminophen if recommended by the doctor, but avoid NSAIDs if bleeding is a concern.
  • Rotate injection sites and use proper needle size and technique if you are self-administering the medication.
  • Monitor signs such as increased pain, redness, warmth, or pus, and seek medical attention if symptoms worsen.
  • Place a clean gauze pad immediately at the bleeding site and apply direct, firm pressure for several minutes.
  • Raise the affected area above the heart level if possible to decrease blood flow.
  • If the bleeding at the injection site is excessive, does not stop with pressure or is accompanied by other symptoms like pain, redness or swelling, contact your doctor immediately.
  • Apply a cold compress to the affected area after bleeding has stopped to reduce swelling.
  • Rotate the injection site for medicines that require frequent injections to reduce tissue damage and bleeding.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Ryzodeg 100IU/ml Flextouch Pen 3 ml is for subcutaneous (under the skin) use only. However, in rare cases, it can be given via infusion intravenously under medical supervision. If you are changing the insulin brand or injecting your insulin by another method, it should be done under strict medical supervision. Cases of heart failure have been reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first hyperglycemia symptoms (high blood sugar level) may include excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may either increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Ryzodeg 100IU/ml Flextouch Pen 3 ml may decrease the level of potassium, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma, and even death. Do not take Ryzodeg 100IU/ml Flextouch Pen 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug-Drug Interactions

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Severe
Insulin degludecGrepafloxacin
Severe

Drug-Drug Interactions

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Severe
How does the drug interact with Ryzodeg 100IU/ml Flextouch Pen 3 ml:
Taking Ryzodeg 100IU/ml Flextouch Pen 3 ml with cinoxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Ryzodeg 100IU/ml Flextouch Pen 3 ml and Cinoxacin, it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin degludecGrepafloxacin
Severe
How does the drug interact with Ryzodeg 100IU/ml Flextouch Pen 3 ml:
Taking Ryzodeg 100IU/ml Flextouch Pen 3 ml with grepafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Ryzodeg 100IU/ml Flextouch Pen 3 ml and grepafloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Ryzodeg 100IU/ml Flextouch Pen 3 ml:
Taking Ryzodeg 100IU/ml Flextouch Pen 3 ml with Gatifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia less frequently.

How to manage the interaction:
There could be a possible interaction between insulin aspart and Gatifloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Ryzodeg 100IU/ml Flextouch Pen 3 ml:
Taking Ryzodeg 100IU/ml Flextouch Pen 3 ml with Enoxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia(low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Ryzodeg 100IU/ml Flextouch Pen 3 ml and cinoxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin degludecLomefloxacin
Severe
How does the drug interact with Ryzodeg 100IU/ml Flextouch Pen 3 ml:
Taking Ryzodeg 100IU/ml Flextouch Pen 3 ml with Lomefloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Ryzodeg 100IU/ml Flextouch Pen 3 ml and Lomefloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Ryzodeg 100IU/ml Flextouch Pen 3 ml:
Taking Ryzodeg 100IU/ml Flextouch Pen 3 ml with nalidixic acid affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Ryzodeg 100IU/ml Flextouch Pen 3 ml and nalidixic but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Ryzodeg 100IU/ml Flextouch Pen 3 ml:
Taking Ryzodeg 100IU/ml Flextouch Pen 3 ml with norfloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Ryzodeg 100IU/ml Flextouch Pen 3 ml and norfloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ryzodeg 100IU/ml Flextouch Pen 3 ml:
Coadministration of levofloxacin and Ryzodeg 100IU/ml Flextouch Pen 3 ml can sometimes affect blood glucose levels - Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose).

How to manage the interaction:
Although using levofloxacin and Ryzodeg 100IU/ml Flextouch Pen 3 ml at the same time may cause an interaction, they can be taken together if a doctor has prescribed it. Inform doctor if you develop hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose), or if you have trouble controlling your blood glucose. Hypoglycemia symptoms include headache, dizziness, tiredness, anxiety, disorientation, a shaking sensation, nausea, hunger, weakness, sweating, palpitation, and a rapid pulse. Hyperglycemia symptoms include Increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ryzodeg 100IU/ml Flextouch Pen 3 ml:
Taking Ryzodeg 100IU/ml Flextouch Pen 3 ml with Moxifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Ryzodeg 100IU/ml Flextouch Pen 3 ml and Moxifloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience headache, dizziness, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, and increased urination. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ryzodeg 100IU/ml Flextouch Pen 3 ml:
Taking Ryzodeg 100IU/ml Flextouch Pen 3 ml with sparfloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia less frequently.

How to manage the interaction:
There could be a possible interaction between Ryzodeg 100IU/ml Flextouch Pen 3 ml and sparfloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercise may lower your body’s need for insulin during and for some time after the physical activity.
  • Exercise may also speed up an insulin dose effect, especially if the exercise involves the injection site area (for example, the leg should not be used for injection just before running). 
  • Discuss with your doctor how you should adjust your insulin regimen to accommodate exercise. 
  • Avoid eating sugar food and prefer food cooked food low in calories.
  • When travelling across more than 2 time zones, you should talk to your doctor about your insulin schedule adjustments.

Side Effects of Ryzodeg 100IU/ml Flextouch Pen 3 ml

  • Rashes
  • Injection site allergic reaction
  • Weight gain
  • Edema (swelling)
  • Lipodystrophy (skin thickening or pits at the injection site)
  • Hypoglycemia (low blood glucose level)
  • Itching

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Ryzodeg 100IU/ml Flextouch Pen 3 ml Substitute

Substitutes safety advice

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Ryzodeg 100IU/ml Flextouch Pen 3 ml can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Ryzodeg 100IU/ml Flextouch Pen 3 ml can be given to you or not depending on your present condition. Ryzodeg 100IU/ml Flextouch Pen 3 ml should be avoided in patients who are allergic to Ryzodeg 100IU/ml Flextouch Pen 3 ml or other forms of insulin, patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycemia), and low potassium level (hypokalaemia).

Cold sweat, cool pale skin, headache; rapid heartbeat, feeling sick, feeling very hungry, temporary vision changes, drowsiness, unusual tiredness and weakness, nervousness or tremor, feeling anxious, feeling confused, difficulty in concentrating are some of the common signs of the low blood sugar level in an individual.

If you experience low blood sugar, eat glucose tablets or another high sugar snack (e.g. sweets, biscuits, fruit juice). Measure your blood sugar if possible and rest. Always carry glucose tablets or high sugar snacks with you. You should give a call to any of your family members if you are feeling dizziness or drowsiness. Consult a doctor immediately.

It is advised to tell all the medicines that you are using to your doctor like pioglitazone or rosiglitazone as taking other diabetes medicines may increase the risk of serious heart problems.

Local allergic reactions (pain, redness, hives, inflammation, bruising, swelling, and itching) at the injection site may occur. These usually disappear after a few weeks of taking your insulin. If they do not disappear, or if they spread throughout your body, talk to your doctor immediately.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • ISONIAZID
  • PENTAMIDINE
  • CIPROFLOXACIN
  • GLUCAGON
  • DANAZOL
  • METFORMIN
  • RESERPINE
  • NIACIN
  • ATENOLOL
  • ACEBUTOLOL
  • METOPROLOL
  • LEVOTHYROXINE
  • FLUOXETINE
  • LITHIUM
  • PROGESTERONE
  • ESTROGEN

Special Advise

  • Your doctor may tell you to have a regular potassium level as prolonged administration causes a life-threatening hypokalemia condition (low potassium). 
  • Store Ryzodeg 100IU/ml Flextouch Pen 3 ml between 2-8 degree celsius temperature only. Do not store Ryzodeg 100IU/ml Flextouch Pen 3 ml in the freezer. 

Disease/Condition Glossary

Type 1 diabetes mellitus: In type 1 diabetes mellitus, our body does not make insulin (the hormone which helps to decrease sugar levels in the blood) to control blood sugar levels.

Type 2 diabetes mellitus: In type 2 diabetes mellitus, either the body stops producing enough insulin, or there is resistance to the action of insulin. As a result, insulin is produced in sufficient amounts but is unable to act on the tissues of the organs.

Have a query?

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Ryzodeg 100IU/ml Flextouch Pen 3 ml to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

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Pregnancy

Safe if prescribed

Ryzodeg 100IU/ml Flextouch Pen 3 ml can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery.

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Breast Feeding

Safe if prescribed

Ryzodeg 100IU/ml Flextouch Pen 3 ml can be given safely to nursing mothers but only under the supervision of a doctor.

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Driving

Unsafe

Drive with caution, Ryzodeg 100IU/ml Flextouch Pen 3 ml usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycemia (low blood sugar).

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Liver

Caution

Ryzodeg 100IU/ml Flextouch Pen 3 ml to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Ryzodeg 100IU/ml Flextouch Pen 3 ml to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Ryzodeg 100IU/ml Flextouch Pen 3 ml can be given safely to children; dose has to be prescribed under the supervision of a doctor.

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