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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Composition

SELEGILINE-5MG

Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Selgin Tablet 10's

Selgin Tablet 10's belongs to a class of antiparkinson drugs called monoamine oxidase-B inhibitors used in the treatment of Parkinson’s disease. Parkinson’s disease is a central nervous system disorder that affects movement. It causes stiffness, shaking, difficulty in walking, coordination and balance. In Parkinson’s patients, there is a decrease in dopamine (a chemical messenger that is important for movement control) levels as the nerve cells that produce dopamine begin to die.

Selgin Tablet 10's contains Selegiline that works by inhibiting the action of an enzyme called monoamine oxidase-B that naturally breaks down dopamine. Thereby, increases the level of dopamine and restores its level in the brain thereby improving the symptoms of Parkinson’s disease.

Take Selgin Tablet 10's with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you how often you take Selgin Tablet 10's based on your medical condition. Some people may experience a sore mouth, swollen gums, loss of balance, difficulty in controlling movements, headache, dizziness, nausea, sleep disorders, mouth ulcers or constipation. Most of these side effects of Selgin Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Selgin Tablet 10's or any other medicines, please tell your doctor. Avoid taking Selgin Tablet 10's if you are pregnant or breastfeeding and consult a doctor. Selgin Tablet 10's is not recommended for children. If you are about to undergo any surgery, please inform your doctor that you are taking Selgin Tablet 10's as it may interact with certain medicines used as a part of general anaesthesia. Avoid taking Selgin Tablet 10's if you have stomach or duodenal ulcers, angina (chest pain), high blood pressure, major heart or blood vessel problems, hyperthyroidism (overactive thyroid gland), fast or irregular heartbeat, narrow-angle glaucoma, pheochromocytoma (tumour of the adrenal gland), prostatic adenoma (tumour of prostate gland), schizophrenia, advanced dementia (loss of memory and other thinking abilities). If you have sleep problems, anxiety, a history of stomach ulcers, kidney or liver problems, any unusual urges like excessive gambling or increased sexual behaviour, inform your doctor before taking Selgin Tablet 10's.

Uses of Selgin Tablet 10's

Parkinson’s disease

Directions for Use

Take Selgin Tablet 10's as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, break or chew it.

Medicinal Benefits

Selgin Tablet 10's is an antiparkinson agent that is used in the treatment of Parkinson’s disease. In Parkinson’s patients, the nerve cells that produce dopamine (a chemical messenger that is important for movement control) begin to die. So, there is a decrease in dopamine levels. Selgin Tablet 10's works by inhibiting the action of the monoamine oxidase-B enzyme that naturally breaks down dopamine. Thereby, increases dopamine in the brain and restores its levels. Thus, it improves the symptoms of Parkinson’s disease. Selgin Tablet 10's can be used alone or in combination with other medicines such as levodopa to reduce uncontrolled movements.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Selgin Tablet 10's

  • Sore mouth
  • Swollen gums
  • Loss of balance
  • Difficulty in controlling movements
  • Headache
  • Dizziness
  • Nausea
  • Sleep disorders
  • Mouth ulcers
  • Constipation

Drug Warnings

If you are known to be allergic to Selgin Tablet 10's or any other medicines, please tell your doctor. Avoid taking Selgin Tablet 10's if you are pregnant or breastfeeding and consult a doctor. Selgin Tablet 10's is not recommended for children. If you are about to undergo any surgery, please inform your doctor that you are taking Selgin Tablet 10's as it may interact with certain medicines used as a part of general anaesthesia. Avoid taking Selgin Tablet 10's if you have stomach or duodenal ulcers, angina (chest pain), high blood pressure, major heart or blood vessel problems, hyperthyroidism (overactive thyroid gland), fast or irregular heartbeat, narrow-angle glaucoma, pheochromocytoma (tumour of the adrenal gland), prostatic adenoma (tumour of the prostate gland), schizophrenia, advanced dementia (loss of memory and other thinking abilities). If you have sleep problems, anxiety, a history of stomach ulcers, kidney or liver problems, unusual urges like excessive gambling or increased sexual behaviour, inform your doctor before taking Selgin Tablet 10's.

Drug-Drug Interactions

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SelegilineCarbamazepine
Critical
SelegilineDopamine
Critical

Drug-Drug Interactions

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SelegilineCarbamazepine
Critical
How does the drug interact with Selgin Tablet:
Taking Carbamazepine with Selgin Tablet can cause serotonin syndrome. (Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selgin Tablet with Carbamazepine is not recommended, but it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
SelegilineDopamine
Critical
How does the drug interact with Selgin Tablet:
When Selgin Tablet is taken with Dopamine, may significantly increase high blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Dopamine and Selgin Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
SelegilineDuloxetine
Critical
How does the drug interact with Selgin Tablet:
Taking duloxetine with Selgin Tablet may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Although there is an interaction between Duloxetine and Selgin Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
SelegilineMethadone
Critical
How does the drug interact with Selgin Tablet:
Co-administration of Selgin Tablet with Methadone can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selgin Tablet with Methadone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
SelegilineCitalopram
Critical
How does the drug interact with Selgin Tablet:
Co-administration of Selgin Tablet with Citalopram can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selgin Tablet with Citalopram together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
SelegilinePheniramine
Critical
How does the drug interact with Selgin Tablet:
Using pheniramine with selageline can cause severe high blood pressure

How to manage the interaction:
Taking Pheniramine with Selgin Tablet is not recommended, but it should be taken if prescribed by a doctor. However, if you experience headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SelegilineRasagiline
Critical
How does the drug interact with Selgin Tablet:
Co-administration of Selgin Tablet with Rasagiline can increase the risk of high blood pressure.

How to manage the interaction:
Although there is a possible interaction between Selgin Tablet and Rasagiline, but can be taken together if prescribed by a doctor. However, if you experience confusion, hallucination (seeing or hearing things that do not exist), fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
SelegilineSertraline
Critical
How does the drug interact with Selgin Tablet:
Co-administration of Sertraline with Selgin Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selgin Tablet with Sertraline together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SelegilineAmitriptyline
Critical
How does the drug interact with Selgin Tablet:
Co-administration of Amitriptyline together with Selgin Tablet can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).

How to manage the interaction:
Although using Selgin Tablet and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
SelegilineNortriptyline
Critical
How does the drug interact with Selgin Tablet:
Co-administration of Nortriptyline with Selgin Tablet might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Nortriptyline with Selgin Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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SELEGILINE-5MGTyramine-containing food
Moderate

Drug-Food Interactions

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SELEGILINE-5MGTyramine-containing food
Moderate
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Consuming Selgin Tablet with Tyramine-containing food it may increase the blood pressure. Avoid consuming Selgin Tablet with Tyramine-containing food.

Diet & Lifestyle Advise

  • Avoid intake of tyramine rich foods such as broad beans, Bovril, mature cheese, fermented soya bean products or yeast extracts.
  • Eat more fibre rich foods to ease constipation.
  • Drink plenty of water to avoid headaches due to dehydration.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPARKINSON AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RASAGILINE
  • LEVODOPA
  • DOPAMINE
  • AMANTADINE
  • ESCITALOPRAM
  • CITALOPRAM
  • FLUVOXAMINE
  • FLUOXETINE
  • SERTRALINE
  • PAROXETINE
  • PROTRIPTYLINE
  • AMITRIPTYLINE
  • VENLAFAXINE
  • DULOXETINE
  • PETHIDINE
  • TRAMADOL
  • CODEINE
  • MEPERIDINE
  • LINEZOLID
  • SUMATRIPTAN
  • ZOLMITRIPTAN
  • RIZATRIPTAN
  • DIGITALIS
  • CLONAZEPAM
  • IBUPROFEN
  • NARATRIPTAN
  • ALTRETAMINE

Special Advise

  • Selgin Tablet 10's may cause abnormalities in certain laboratory test results such as liver function tests and blood tests. Therefore, inform your doctor or lab technician that you are on treatment with Selgin Tablet 10's before undergoing any tests.
  • Selgin Tablet 10's should not be used at daily doses of more than 2.5 mg/day due to the risks associated with a change in the amount of chemical messenger in the brain called a neurotransmitter. 
  • Selgin Tablet 10's is contraindicated for use with medicine containing meperidine, as serious reactions have been experienced in patients taking both medications together. 

Disease/Condition Glossary

Parkinson’s disease: It is a disorder of the central nervous system that affects movement due to nerve cell damage in the brain which decreases the levels of dopamine and leads to symptoms such as stiffness, tremor in one hand, shaking, difficulty in walking, coordination, and balance. This condition can last for many years or life-long. Treatment with medicines along with physiotherapy may help to control the symptoms and provide a quality life for as long as possible.

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