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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Simlo EZ 10 mg Tablet 10's

Simlo EZ 10 mg Tablet 10's belongs to the class of medicines called 'anti hyperlipidemic drugs' or cholesterol-lowering agents primarily used to lower bad cholesterol and triglycerides (type of fat) and increase good cholesterol levels. This reduces the risk of heart attack and stroke in future. High cholesterol, known as hyperlipidemia or dyslipidemia, occurs when there is an excess of the unhealthy cholesterol balance in the blood. When the cholesterol level is high in the blood, your arteries get narrowed and clogged, contributing to heart diseases like stroke and heart attack. 

Simlo EZ 10 mg Tablet 10's is a combination of Ezetimibe and Simvastatin. Ezetimibe works by reducing the cholesterol absorbed in the digestive tract. Simvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. 

Take Simlo EZ 10 mg Tablet 10's as prescribed. Your doctor will advise how often you take Simlo EZ 10 mg Tablet 10's based on your medical condition. Sometimes, this medicine may cause common side effects such as muscle pain, headache, diarrhoea, upper respiratory tract infection or increased liver enzyme levels. Most of these side effects of Simlo EZ 10 mg Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Ezetimibe, Simvastatin or other medicines, please tell your doctor. If you are aged 65 years or older, please inform your doctor. Avoid using Simlo EZ 10 mg Tablet 10's if you are pregnant. Also, you are advised to take effective birth control measures while taking Simlo EZ 10 mg Tablet 10's to avoid pregnancy. Please inform your doctor if you are a breastfeeding mother. Simlo EZ 10 mg Tablet 10's is not recommended for children below 10 years of age as the safety and effectiveness were not established. If you feel dizzy after taking Simlo EZ 10 mg Tablet 10's, avoid driving or operating machinery. 

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Simlo EZ 10 mg Tablet 10's

High cholesterol, Prevention of heart attack and stroke

Medicinal Benefits

Simlo EZ 10 mg Tablet 10's contains Ezetimibe and Simvastatin, used to lower the levels of bad cholesterol and triglycerides (type of fat) and increase good cholesterol levels. This reduces the risk of heart attack and stroke in future. Ezetimibe works by reducing the cholesterol absorbed in the digestive tract. Simvastatin works by inhibiting the production of cholesterol your body makes by itself. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Simlo EZ 10 mg Tablet 10's is used for patients whose cholesterol levels are not controlled by diet and exercise alone. 

Side Effects of Simlo EZ 10 mg Tablet 10's

  • Muscle pain
  • Headache
  • Diarrhoea
  • Upper respiratory tract infection
  • Increased liver enzyme levels

Directions for Use

Take Simlo EZ 10 mg Tablet 10's with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Ezetimibe, Simvastatin or any other medicines, please tell your doctor. If you are aged 65 years or older, please inform your doctor. Avoid using Simlo EZ 10 mg Tablet 10's if you are pregnant. Also, you are advised to take effective birth control measures while taking Simlo EZ 10 mg Tablet 10's to avoid pregnancy. Please inform your doctor if you are a breastfeeding mother. Simlo EZ 10 mg Tablet 10's is not recommended for children below 10 years of age as the safety and effectiveness were not established. If you feel dizzy after taking Simlo EZ 10 mg Tablet 10's, avoid driving or operating machinery. Maintain a low-fat diet along with Simlo EZ 10 mg Tablet 10's for effective results. If you have diabetes or are at risk of developing diabetes, your doctor will monitor you closely while on treatment with Simlo EZ 10 mg Tablet 10's. You are likely to be at risk of developing diabetes if you have high levels of sugars and fats in the blood, high blood pressure and are overweight.

Therapeutic Class

ANTILIPEMICS

Drug-Drug Interactions

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SimvastatinItraconazole
Critical
SimvastatinDarunavir
Critical

Drug-Drug Interactions

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SimvastatinItraconazole
Critical
How does the drug interact with Simlo EZ 10 mg Tablet 10's:
Simlo EZ 10 mg Tablet 10's's blood levels and effects may be greatly increased when combined with itraconazole.

How to manage the interaction:
Simlo EZ 10 mg Tablet 10's and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you have side effects such unexplained pain in the muscles or tenderness, muscle weakness, fever or flu-like symptoms, or dark urine. Without consulting a doctor, never stop taking any medication.
SimvastatinDarunavir
Critical
How does the drug interact with Simlo EZ 10 mg Tablet 10's:
Combining Darunavir and Simlo EZ 10 mg Tablet 10's can increase the blood levels and effects of Simlo EZ 10 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Darunavir and Simlo EZ 10 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinNefazodone
Critical
How does the drug interact with Simlo EZ 10 mg Tablet 10's:
Combining Nefazodone and Simlo EZ 10 mg Tablet 10's can increase the blood levels and effects of Simlo EZ 10 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Nefazodone and Simlo EZ 10 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinDanazol
Critical
How does the drug interact with Simlo EZ 10 mg Tablet 10's:
Combining Danazol and Simlo EZ 10 mg Tablet 10's can increase the blood levels and effects of Simlo EZ 10 mg Tablet 10's.

How to manage the interaction:
Taking Danazol and Simlo EZ 10 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinPosaconazole
Critical
How does the drug interact with Simlo EZ 10 mg Tablet 10's:
Taking Posaconazole with Simlo EZ 10 mg Tablet 10's can increase the blood levels and effects of Simlo EZ 10 mg Tablet 10's. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Posaconazole and Simlo EZ 10 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinAtazanavir
Critical
How does the drug interact with Simlo EZ 10 mg Tablet 10's:
Combining Atazanavir and Simlo EZ 10 mg Tablet 10's can increase the blood levels and effects of Simlo EZ 10 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Atazanavir and Simlo EZ 10 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-coloured urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinTelithromycin
Critical
How does the drug interact with Simlo EZ 10 mg Tablet 10's:
Combining Telithromycin and Simlo EZ 10 mg Tablet 10's can increase the blood levels and effects of Simlo EZ 10 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Telithromycin and Simlo EZ 10 mg Tablet 10's together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinNelfinavir
Critical
How does the drug interact with Simlo EZ 10 mg Tablet 10's:
Combining Nelfinavir and Simlo EZ 10 mg Tablet 10's can increase the blood levels and effects of Simlo EZ 10 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Nelfinavir and Simlo EZ 10 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinVoriconazole
Critical
How does the drug interact with Simlo EZ 10 mg Tablet 10's:
Taking Voriconazole and Simlo EZ 10 mg Tablet 10's can increase the blood levels and effects of Simlo EZ 10 mg Tablet 10's. This can increase the risk of side effects (liver damage and rhabdomyolysis - involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Voriconazole and Simlo EZ 10 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if a doctor advises. However, if you experience muscle pain, fever or dark-colored urine, vomiting, and yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinFosamprenavir
Critical
How does the drug interact with Simlo EZ 10 mg Tablet 10's:
Combining Fosamprenavir and Simlo EZ 10 mg Tablet 10's can increase the blood levels and effects of Simlo EZ 10 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Fosamprenavir and Simlo EZ 10 mg Tablet 10's together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • POSACONAZOLE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • INDINAVIR
  • SAQUINAVIR
  • NELFINAVIR
  • TIPRANAVIR
  • RITONAVIR
  • ATAZANAVIR
  • NEFAZODONE
  • COBICISTAT
  • DANAZOL
  • CYCLOSPORINE
  • TELAPREVIR
  • BOCEPREVIR
  • FENOFIBRATE
  • LOMITAPIDE
  • GEMFIBROZIL
  • AMIODARONE
  • DRONEDARONE
  • DILTIAZEM
  • VERAPAMIL
  • RANOLAZINE
  • AMLODIPINE
  • COLCHICINE
  • NIACIN
  • WARFARIN

Diet & Lifestyle Advise

  • Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
  • Eat a healthy diet that includes fruits, vegetables, fish, poultry, whole grains, nuts and cut-down beverages, and processed and sugary foods.
  • Do regular exercises such as swimming, cycling, walking, or dancing and focus on losing weight, as obesity also raises bad cholesterol and lowers good cholesterol.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Special Advise

  • Regular blood tests are recommended to monitor liver function while on treatment with Simlo EZ 10 mg Tablet 10's.

Author Details

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Disease/Condition Glossary

High cholesterol: It is also known as hyperlipidemia or dyslipidemia and occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol. There are two types of cholesterol found in our body: good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol in our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.

Simlo EZ 10 mg Tablet 10's Substitute

Substitutes safety advice
  • SIMVOTIN EZ 10MG TABLET

    23.13per tablet
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