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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
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Whats That

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Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Mac Healthcare India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Skip-5 Tablet

Skip-5 Tablet belongs to the class of medicines called progestogens used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Skip-5 Tablet may be used in the treatment of breast cancer. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain.

Skip-5 Tablet contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Take Skip-5 Tablet as prescribed by your doctor. You are advised to take Skip-5 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhea, headache, breast pain, and tenderness. Most of these side effects of Skip-5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Skip-5 Tablet or any other medicines, please tell your doctor. Skip-5 Tablet is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking Skip-5 Tablet . It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Skip-5 Tablet . You are advised to stop smoking while taking Skip-5 Tablet as it may increase the risk of adverse effects.

Uses of Skip-5 Tablet

Heavy, painful or irregular periods, Premenstrual syndrome (PMS), Endometriosis, Breast cancer

Directions for Use

Take Skip-5 Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Skip-5 Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Storage

Keep Skip-5 Tablet out of reach and sight of children.

Drug Warnings

If you are allergic to Skip-5 Tablet or any other medicines, please tell your doctor. Skip-5 Tablet is not recommended for pregnant women as it may harm an unborn baby. If you are breastfeeding, consult a doctor before taking Skip-5 Tablet . It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Skip-5 Tablet . You are advised to stop smoking while taking Skip-5 Tablet as it may increase the risk of adverse effects. If you are about to undergo any surgery, please inform your doctor that you are taking Skip-5 Tablet as it may increase the effect of certain anesthetics. If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking Skip-5 Tablet and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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NorethisteroneEtretinate
Severe

Drug-Drug Interactions

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NorethisteroneEtretinate
Severe
How does the drug interact with Skip-5 Tablet:
Using Etretinate and Skip-5 Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Skip-5 Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
How does the drug interact with Skip-5 Tablet:
Coadministration of Skip-5 Tablet with Topiramate can reduce the blood levels and effects of norethindrone in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Skip-5 Tablet and topiramate together can result in an interaction; it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, hot flashes or vaginal dryness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Skip-5 Tablet:
Coadministration of Skip-5 Tablet with Rifabutin can reduce the blood levels and effects of norethindrone.This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Skip-5 Tablet with Rifabutin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Skip-5 Tablet:
Coadministration of Skip-5 Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Skip-5 Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Skip-5 Tablet:
Coadministration of Skip-5 Tablet and Mycophenolic acid can decrease the levels and effects of Skip-5 Tablet.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Skip-5 Tablet, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Skip-5 Tablet:
Using Felbamate and Skip-5 Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Skip-5 Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Skip-5 Tablet:
Taking Skip-5 Tablet with rifampicin can decrease the blood levels of Skip-5 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Skip-5 Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneFosphenytoin
Severe
How does the drug interact with Skip-5 Tablet:
Coadministration of Skip-5 Tablet with Fosphenytoin can reduces the blood levels and effects of Skip-5 Tablet .

How to manage the interaction:
Taking Skip-5 Tablet with Fosphenytoin together can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms of abnormal bleeding while using birth control, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Skip-5 Tablet:
Coadministration of Acitretin with Skip-5 Tablet may interfere with the contraceptive effect of Skip-5 Tablet.

How to manage the interaction:
Acitretin and Skip-5 Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.
NorethisteroneTelaprevir
Severe
How does the drug interact with Skip-5 Tablet:
Using Telaprevir and Skip-5 Tablet together can increase risk of unintended pregnancy and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Telaprevir with Skip-5 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Skip-5 Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Skip-5 Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Skip-5 Tablet dose.

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Side Effects of Skip-5 Tablet

  • Unusual vaginal bleeding or spotting
  • Dizziness
  • Dry mouth
  • Constipation
  • Abdominal pain/cramps
  • Nausea
  • Diarrhea
  • Headache
  • Breast pain and tenderness

Habit Forming

No

Therapeutic Class

PROGESTIN

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Skip-5 Tablet contains Norethisterone, a synthetic hormone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Skip-5 Tablet may be used to delay periods. Skip-5 Tablet keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Skip-5 Tablet .

Skip-5 Tablet may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoking, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Skip-5 Tablet .

You are not recommended to take Skip-5 Tablet with rifampicin as it may decrease the levels of Skip-5 Tablet in blood and reduce its effectiveness. However, please consult a doctor before taking Skip-5 Tablet with other medicines.

Periods usually resume within 3 days of discontinuing Skip-5 Tablet . However, please consult a doctor if you have any concerns regarding this.

Skip-5 Tablet may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Skip-5 Tablet and inform your doctor if you have diabetes before taking Skip-5 Tablet .

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • NELFINAVIR
  • RITONAVIR
  • AMINOGLUTETHIMIDE
  • COTRIMOXAZOLE
  • RIFAMPICIN
  • TETRACYCLINE
  • CICLOSPORIN

Special Advise

  • Skip-5 Tablet may interfere with certain laboratory tests. Therefore, inform your doctor that you are taking Skip-5 Tablet before undergoing any tests.

Disease/Condition Glossary

Endometriosis: It is a disorder in which the tissue lining the uterus (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain. Other symptoms of endometriosis include lower back pain, painful periods, heavy menstrual bleeding, pain following sexual intercourse, or discomfort with bowel movements. 

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