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MRP ₹14468.5
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Whats That
About Spegra Tablet
Spegra Tablet belongs to the group of antiretroviral agents indicated for the treatment of HIV-1 infection in adults and children above 12years weighing at least 40kgs. HIV is a virus that attacks the body's immune system, making it compromised and susceptible to various infections and diseases.
Spegra Tablet contains 'Dolutegravir, Emtricitabine and Tenofovir alafenamide'. Spegra Tablet works by interfering with the working of HIV-1 reverse transcriptase enzymes which are necessary for the replication of the virus. Together, Spegra Tablet helps in treating HIV infection.
Take Spegra Tablet as prescribed. In some cases, Spegra Tablet may cause certain side effects such as trouble sleeping, headache, nausea, and tiredness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
Consult your doctor if you are pregnant, or planning to get pregnant. Avoid breastfeeding while taking Spegra Tablet . Spegra Tablet does not help reduce the risk of getting HIV-1 infection by sexual contact; therefore, it is important to practise safe sex to avoid transmitting HIV to your partner. Avoid alcohol consumption while on treatment with Spegra Tablet .
Uses of Spegra Tablet
Directions for Use
Medicinal Benefits
Spegra Tablet is an anti-retroviral drug used in the treatment of HIV-1 infection. Spegra Tablet works by interfering with the replication of HIV and preventing its further progression. It contains Dolutegravir, Emtricitabine and Tenofovir alafenamide. Dolutegravir works by blocking HIV integrase, which is responsible for integrating viral DNA into the host cell. Thus, it inhibits the integration of the viral component into the human body cells. Emtricitabine works by inhibiting reverse transcriptase, which is responsible for transcribing RNA to DNA. By blocking this action, emtricitabine prevents the proliferation of the virus. Tenofovir alafenamide blocks the enzyme polymerase, thereby preventing aggregation of viral components and terminating the DNA chain, thus effectively nipping viral replication in the bud.
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Drug Warnings
Inform the doctor if you are allergic to any of the components of Spegra Tablet . Consult your doctor if you are pregnant, or planning to get pregnant before taking Spegra Tablet . Avoid breastfeeding while on treatment with Spegra Tablet . Avoid alcohol consumption. It is important to practise safe sex to avoid transmitting HIV to your partner. Inform your doctor if you have liver problems, hepatitis infections, heart or kidney problems. Keep your doctor informed about your health condition and medications to rule out any interactions.
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Spegra Tablet works by inhibiting the replication of viral DNA and by preventing it from being integrated into the human body. Thereby, Spegra Tablet helps treat HIV infection.
It is not known if Spegra Tablet is safe for patients who have HIV-1 and hepatitis-B infections. Please consult your doctor for any concerns.
Do not stop taking Spegra Tablet without consulting your doctor as it may reduce the effectiveness of anti-HIV therapy. Continue taking Spegra Tablet for as long as your doctor has prescribed it to you to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Spegra Tablet .
Spegra Tablet might cause lactic acidosis (excess of lactic acid in the blood). Consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, or deep rapid breathing.
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Disease/Condition Glossary
HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. HIV spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs.
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