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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About STARSTAT 40MG TABLET

STARSTAT 40MG TABLET belongs to a group of antilipemic medicines called 'lipid-lowering agents' used to lower the levels of increased cholesterol in the body. Additionally, STARSTAT 40MG TABLET is also used to lower the risk of heart diseases such as heart attack or stroke. High cholesterol levels might cause a build-up of cholesterol on the arteries walls, leading to blockage of blood flow to the heart and other body parts that could cause heart disease, heart attack or stroke.

STARSTAT 40MG TABLET contains 'Simvastatin' that works by blocking HMG-CoA reductase, an enzyme necessary for cholesterol production in the body. STARSTAT 40MG TABLET helps lower the levels of LDL (bad) cholesterol, and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, STARSTAT 40MG TABLET lowers the raised levels of fats, triglycerides and cholesterol, which lowers the risk of heart attack or stroke. 

You are advised to take STARSTAT 40MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition. You may experience certain common side-effects such as headache, stomach pain, constipation, and nausea in some cases. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Do not take STARSTAT 40MG TABLET if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Stop taking STARSTAT 40MG TABLET and consult a doctor immediately if you become pregnant while taking STARSTAT 40MG TABLET. STARSTAT 40MG TABLET may cause dizziness, so be cautious while driving. Avoid consuming alcohol with STARSTAT 40MG TABLET as it could lead to increased dizziness. STARSTAT 40MG TABLET is not recommended for children below 10 years as safety and effectiveness have not been established. Inform your doctor regarding your health condition and the medicines you are taking to rule out any side effects or interactions.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

SIMVASTATIN-40MG

Manufacturer/Marketer

Lupin Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of STARSTAT 40MG TABLET

Hyperlipidaemia (high cholesterol)

Medicinal Benefits

STARSTAT 40MG TABLET contains 'Simvastatin', which belongs to a group of lipid-lowering agents called HMG-CoA reductase inhibitors to lower the increased levels of cholesterol or fat. STARSTAT 40MG TABLET works by blocking the HMG-CoA reductase enzyme, which is necessary for cholesterol production in the body. STARSTAT 40MG TABLET helps lower the levels of LDL (bad) cholesterol and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, STARSTAT 40MG TABLET lowers the blood level of fats and cholesterol and helps prevent a heart attack or stroke. STARSTAT 40MG TABLET as an adjunct to dietary measures is used to reduce the risk of having a heart event due to cardiovascular diseases, the incidence of non-fatal heart attack or stroke, the need for revascularisation procedures (restoration of blood flow to the heart), people with diabetes, pre-existing heart disease, and peripheral vascular disease.  

Side Effects of STARSTAT 40MG TABLET

  • Headache
  • Stomach pain
  • Constipation
  • Nausea

Directions for Use

Swallow STARSTAT 40MG TABLET a whole with a glass of water; do not chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take STARSTAT 40MG TABLET if you are allergic to any of its contents; if you are taking fusidic acid or have taken it in the past 7 days. Inform your doctor if you are due to have surgery, drink large amounts of alcohol; if you have liver or kidney problems. Do not take STARSTAT 40MG TABLET if you are pregnant, breastfeeding, think you may be pregnant or if you are trying for pregnancy. Stop taking STARSTAT 40MG TABLET and consult a doctor immediately if you become pregnant while taking STARSTAT 40MG TABLET. STARSTAT 40MG TABLET may cause dizziness, so be cautious while driving. Avoid consuming alcohol with STARSTAT 40MG TABLET as it could lead to increased dizziness. STARSTAT 40MG TABLET is not recommended for children below 10 years as safety and effectiveness have not been established.

Therapeutic Class

ANTILIPEMICS

Drug-Drug Interactions

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SimvastatinItraconazole
Critical
SimvastatinDarunavir
Critical

Drug-Drug Interactions

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SimvastatinItraconazole
Critical
How does the drug interact with STARSTAT 40MG TABLET:
STARSTAT 40MG TABLET's blood levels and effects may be greatly increased when combined with itraconazole.

How to manage the interaction:
STARSTAT 40MG TABLET and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you have side effects such unexplained pain in the muscles or tenderness, muscle weakness, fever or flu-like symptoms, or dark urine. Without consulting a doctor, never stop taking any medication.
SimvastatinDarunavir
Critical
How does the drug interact with STARSTAT 40MG TABLET:
Combining Darunavir and STARSTAT 40MG TABLET can increase the blood levels and effects of STARSTAT 40MG TABLET. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Darunavir and STARSTAT 40MG TABLET together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinNefazodone
Critical
How does the drug interact with STARSTAT 40MG TABLET:
Combining Nefazodone and STARSTAT 40MG TABLET can increase the blood levels and effects of STARSTAT 40MG TABLET. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Nefazodone and STARSTAT 40MG TABLET together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinDanazol
Critical
How does the drug interact with STARSTAT 40MG TABLET:
Combining Danazol and STARSTAT 40MG TABLET can increase the blood levels and effects of STARSTAT 40MG TABLET.

How to manage the interaction:
Taking Danazol and STARSTAT 40MG TABLET together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinPosaconazole
Critical
How does the drug interact with STARSTAT 40MG TABLET:
Taking Posaconazole with STARSTAT 40MG TABLET can increase the blood levels and effects of STARSTAT 40MG TABLET. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Posaconazole and STARSTAT 40MG TABLET together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinAtazanavir
Critical
How does the drug interact with STARSTAT 40MG TABLET:
Combining Atazanavir and STARSTAT 40MG TABLET can increase the blood levels and effects of STARSTAT 40MG TABLET. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Atazanavir and STARSTAT 40MG TABLET together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-coloured urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinTelithromycin
Critical
How does the drug interact with STARSTAT 40MG TABLET:
Combining Telithromycin and STARSTAT 40MG TABLET can increase the blood levels and effects of STARSTAT 40MG TABLET. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Telithromycin and STARSTAT 40MG TABLET together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinNelfinavir
Critical
How does the drug interact with STARSTAT 40MG TABLET:
Combining Nelfinavir and STARSTAT 40MG TABLET can increase the blood levels and effects of STARSTAT 40MG TABLET. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Nelfinavir and STARSTAT 40MG TABLET together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinVoriconazole
Critical
How does the drug interact with STARSTAT 40MG TABLET:
Taking Voriconazole and STARSTAT 40MG TABLET can increase the blood levels and effects of STARSTAT 40MG TABLET. This can increase the risk of side effects (liver damage and rhabdomyolysis - involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Voriconazole and STARSTAT 40MG TABLET together is not recommended as it can lead to an interaction, but it can be taken if a doctor advises. However, if you experience muscle pain, fever or dark-colored urine, vomiting, and yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinFosamprenavir
Critical
How does the drug interact with STARSTAT 40MG TABLET:
Combining Fosamprenavir and STARSTAT 40MG TABLET can increase the blood levels and effects of STARSTAT 40MG TABLET. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Fosamprenavir and STARSTAT 40MG TABLET together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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SIMVASTATIN-40MGGrapefruit and Grapefruit Juice, Vitamin-K rich foods
Severe

Drug-Food Interactions

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SIMVASTATIN-40MGGrapefruit and Grapefruit Juice, Vitamin-K rich foods
Severe
Common Foods to Avoid:
Grapefruit Juice, Grapefruit, Green Tea

How to manage the interaction:
Taking grapefruit or grape juice and green tea or green tea extracts can increase the blood levels of STARSTAT 40MG TABLET and can increase the risk of liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue). Taking grapefruit or grape juice and green tea or green tea extracts can lead to an interaction. However, if you experience any symptoms like muscle pain, tenderness, or weakness during treatment, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Avoid taking grapefruit or grape juice and green tea or green tea extracts.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FUSIDIC ACID
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • INDINAVIR
  • SAQUINAVIR
  • RITONAVIR
  • NELFINAVIR
  • ITRACONAZOLE
  • KETOCONAZOLE
  • POSACONAZOLE
  • VORICONAZOLE
  • BOCEPREVIR
  • TELAPREVIR
  • NEFAZODONE
  • GEMFIBROZIL
  • CYCLOSPORINE
  • DANAZOL
  • COBICISTAT

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption. 
  • Choose healthy fats and cut down on trans-fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

Special Advise

  • Regular blood tests are advised to determine the effect of STARSTAT 40MG TABLET on lipids. 
  • Consult your doctor immediately if you experience muscle pain, weakness, or tenderness, especially if associated with fever or tiredness.
  • Your doctor may recommend blood tests to monitor liver function prior to the start of treatment and during the treatment with STARSTAT 40MG TABLET. Inform your doctor if you notice yellowing of skin or eyes, unusually dark urine, and tiredness.
  • STARSTAT 40MG TABLET might affect test results for liver function and muscle enzyme (creatin-kinase). Inform the person doing the tests that you are taking STARSTAT 40MG TABLET.
  • It is advisable to have complete cholesterol tests (lipid profile test) at least once a year. It will help you to closely monitor your heart health and risk of heart attack and stroke. 

Author Details

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Disease/Condition Glossary

Hyperlipidaemia: Hyperlipidaemia is commonly known as high cholesterol. Cholesterol is a fatty substance that is naturally produced in the liver because every cell uses it. Cholesterol is also found in fatty foods such as cheese, red meat, and eggs. High cholesterol levels might cause a build-up of fat on the arteries' walls, leading to blockage of blood flow to the heart and other body parts that could cause heart disease, heart attack or stroke. Cholesterol is mainly of two types, namely 'bad cholesterol' and 'good cholesterol'. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG) which deposit fat in the arteries leading to their blockage. Good cholesterol consists of high-density lipoprotein (HDL), which prevents the deposition of fats. Risk factors of high cholesterol are a high-fat diet, obesity, lack of physical exercise, and smoking. Usually, there are no specific symptoms of raised or high cholesterol levels, so it is advisable to have complete cholesterol tests (lipid profile tests) at least once a year. It will help monitor your heart health and risk of heart attack or stroke. 

STARSTAT 40MG TABLET Substitute

Substitutes safety advice
  • B Lip 40 Tablet 10's

    31.50per tablet
  • Simvotin 40 mg Tablet 10's

    27.00per tablet
  • Zocor 40 mg Tablet 10's

    18.90per tablet
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