SYNTHIVAN TABLET 30'S

₹3246

(Inclusive of all Taxes)

₹486.9 Cashback (15%)

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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

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Prescription drug

Whats That

About SYNTHIVAN TABLET

SYNTHIVAN TABLET belongs to the class of medications called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

SYNTHIVAN TABLET is a combination of Atazanavir and Ritonavir. These drugs belong to the class of protease inhibitors. They work by inhibiting the protease enzyme production, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication.

Take SYNTHIVAN TABLET exactly as prescribed by the doctor. SYNTHIVAN TABLET may cause side effects such as stomach ache, diarrhoea, feeling sick (nausea), vomiting (being sick), flushing (reddening of the skin), headache, dizziness, pain in the throat, cough, upset stomach, a tingling sensation or numbness in the hands, feet or around the lips and mouth, bad taste in the mouth, damage to the nerves that can cause weakness and pain, itching, rash, joint pain and back pain, dyspepsia (indigestion), and fatigue (tiredness). Inform your doctor if any of these side effects persist or get worse.

It is not recommended to take SYNTHIVAN TABLET if you are allergic to any contents of it. Before taking SYNTHIVAN TABLET , inform your doctor if you have any liver disease, hepatitis B or C (liver infections), hemophilia (bleeding disorder), erectile dysfunction, diabetes, gall stones, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Consult your doctor before using this medicine for children. SYNTHIVAN TABLET should be used with caution in elderly patients. Alcohol consumption may increase the risk of side effects. SYNTHIVAN TABLET may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of SYNTHIVAN TABLET

HIV infection

Directions for Use

Take SYNTHIVAN TABLET as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

SYNTHIVAN TABLET belongs to the group of medicines called antiretroviral therapy (ART). SYNTHIVAN TABLET is a fixed-dose combination (FDC) and contains atazanavir and ritonavir. FDC helps decrease drug resistance (reduction in medication effectiveness) as HIV can easily develop drug resistance. SYNTHIVAN TABLET helps reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It further helps in improving the quality of life of a patient with HIV.

Storage

Keep this medicine out of the sight and reach of children.

Drug Warnings

Inform your doctor if you develop persistent diarrhoea or vomiting, as it may affect the effectiveness of SYNTHIVAN TABLET . SYNTHIVAN TABLET may cause pancreatitis, so inform your doctor if you develop symptoms such as nausea (feeling sick), vomiting, or stomach pain. SYNTHIVAN TABLET may lead to opportunistic infections (infections that occur frequently or severely in patients with weak immune systems), so inform your doctor immediately if you experience symptoms of infection such as muscle weakness, weakness beginning in the hands and feet that progress towards the trunk, palpitations (pounding heartbeat), and tremors. SYNTHIVAN TABLET may destroy bone leading to symptoms such as joint stiffness or pain. It may also cause muscle pain, tenderness, or weakness. SYNTHIVAN TABLET may also cause dizziness and abnormal heartbeat. Inform your doctor immediately if you notice any significant changes in the electrocardiogram (ECG).

Drug-Drug Interactions

RitonavirIsavuconazole

Critical

RitonavirRanolazine

Critical

Drug-Drug Interactions

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RitonavirIsavuconazole

Critical

How does the drug interact with Synthivan Tablet:
Taking Isavuconazole with Synthivan Tablet may significantly increase the blood levels of Isavuconazole, which may increase the risk of side effects.

How to manage the interaction:
Taking Isavuconazole with Synthivan Tablet is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like nausea, vomiting, loose stools, light color stools or dark urine, consult a doctor. Do not discontinue any medications without consulting a doctor.

RitonavirRanolazine

Critical

How does the drug interact with Synthivan Tablet:
Taking Synthivan Tablet and Ranolazine may significantly increase the blood levels and effects of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine with Synthivan Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. In case you experience any symptoms like feeling lightheaded, fainting, or rapid heartbeats, consult a doctor. Do not stop using any medications without a doctor's advice.

RitonavirPhenobarbital

Critical

How does the drug interact with Synthivan Tablet:
Taking Phenobarbital with Synthivan Tablet may significantly reduce the blood levels of Synthivan Tablet.

How to manage the interaction:
Taking Phenobarbital with Synthivan Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. If you notice any unusual symptoms consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

RitonavirNimodipine

Critical

How does the drug interact with Synthivan Tablet:
Taking Nimodipine with Synthivan Tablet can increase the blood levels of Synthivan Tablet, which may lead to increased side effects.

How to manage the interaction:
Taking Nimodipine with Synthivan Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience irregular heart rhythm, swelling, and lightheadedness, contact a doctor. Do not discontinue any medications without consulting a doctor.

RitonavirEplerenone

Critical

How does the drug interact with Synthivan Tablet:
Co-administration of Eplerenone and Synthivan Tablet may significantly increase the blood levels of Eplerenone.

How to manage the interaction:
Taking Synthivan Tablet and Eplerenone together is not recommended as it can lead to an interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

RitonavirSimvastatin

Critical

How does the drug interact with Synthivan Tablet:
Taking Synthivan Tablet and Simvastatin may increase the risk of side effects.

How to manage the interaction:
Taking Simvastatin with Synthivan Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, tiredness, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, contact a doctor. Do not discontinue any medications without consulting a doctor.

RitonavirTolvaptan

Critical

How does the drug interact with Synthivan Tablet:
Taking Synthivan Tablet and Tolvaptan may significantly increase the blood levels of tolvaptan.

How to manage the interaction:
Taking Tolvaptan with Synthivan Tablet is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, fits, contact a doctor. Do not discontinue any medications without consulting a doctor.

RitonavirErgotamine

Critical

How does the drug interact with Synthivan Tablet:
Taking ergotamine with Synthivan Tablet may significantly increase the blood levels and effects of ergotamine.

How to manage the interaction:
Taking Ergotamine with Synthivan Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor. Do not discontinue any medications without consulting a doctor.

RitonavirVoriconazole

Critical

How does the drug interact with Synthivan Tablet:
When Voriconazole is taken with Synthivan Tablet, the amount of Voriconazole in the blood may decrease.

How to manage the interaction:
Taking Voriconazole with Synthivan Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

RitonavirTicagrelor

Critical

How does the drug interact with Synthivan Tablet:
Taking Ticagrelor with Synthivan Tablet may significantly increase the blood levels of Ticagrelor.

How to manage the interaction:
Taking Ticagrelor with Synthivan Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruit as it helps to boost your immune system. Option for lean protein and whole grains.
Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.
Drink more fluids and avoid alcoholic beverages to prevent dehydration.
Wash your hands properly before and after eating.
Make sure you sleep at least 8 hours a day.

Side Effects of SYNTHIVAN TABLET

Stomach ache
Diarrhoea
Feeling sick (nausea)
Vomiting (being sick)
Flushing (reddening of the skin)
Headache
Dizziness
Pain in the throat
Cough
Upset stomach
A tingling sensation or numbness in the hands, feet or around the lips and mouth
Bad taste in the mouth
Damage to the nerves that can cause weakness and pain
Itching
Rash
Joint pain and back pain
Dyspepsia (indigestion)
Fatigue (tiredness)

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

SYNTHIVAN TABLET Substitute

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does SYNTHIVAN TABLET work?

SYNTHIVAN TABLET is a combination of two medicines: Atazanavir and Ritonavir. These two drugs work by inhibiting the protease enzyme production, which is required by the HIV-infected cells to make new viruses. Thereby preventing viral replication and controlling the infection.

Can I take SYNTHIVAN TABLET with food?

SYNTHIVAN TABLET should be taken with food (after a meal or substantial snack) as this helps in effective absorption of the medicine.

What are the side-effects of SYNTHIVAN TABLET ?

SYNTHIVAN TABLET may cause side-effects such as stomach ache, diarrhoea, feeling sick (nausea), vomiting (being sick), flushing (reddening of the skin), headache, dizziness, pain in the throat, cough, upset stomach, a tingling sensation or numbness in the hands, feet or around the lips and mouth, bad taste in the mouth, damage to the nerves that can cause weakness and pain, itching, rash, joint pain and back pain, dyspepsia (indigestion), and fatigue (tiredness). Inform your doctor if any of these side-effects persist or get worse.

In which conditions should I avoid taking SYNTHIVAN TABLET ?

SYNTHIVAN TABLET should not be used in patients with liver disease, hepatitis B or C (liver infections), haemophilia (bleeding disorder), erectile dysfunction, diabetes, gall stones, and kidney disease as it may worsen these conditions.

Does SYNTHIVAN TABLET cure HIV infection?

SYNTHIVAN TABLET doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.

Drug-Drug Interactions Checker List

ASTEMIZOLE
TERFENADINE
AMIODARONE
BEPRIDIL
DRONEDARONE
FLECAINIDE
PROPAFENONE
QUINIDINE
ERGOTAMINE
ERGONOVINE
METHYLERGONOVINE
DIAZEPAM
ESTAZOLAM
FLURAZEPAM
TRIAZOLAM
MIDAZOLAM
CLOZAPINE
PIMOZIDE
QUETIAPINE
LURASIDONE
HYPERICUM PERFORATUM
RANOLAZINE
PETHIDINE
BUPRENORPHINE
PROPOXYPHENE
CISAPRIDE
RIFABUTIN
VORICONAZOLE
ATORVASTATIN
LOMITAPIDE
ROSUVASTATIN
IRINOTECAN
ALFUZOSIN
FUSIDIC ACID
SILDENAFIL
AVANAFIL
VARDENAFIL
TADALAFIL
COLCHICINE
SALMETEROL
WARFARIN
DILTIAZEM
LIDOCAINE
VERAPAMIL
DIGOXIN
ETHINYLESTRADIOL
CYCLOSPORINE
TACROLIMUS
SIROLIMUS
PIROXICAM

Special Advise

SYNTHIVAN TABLET may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking SYNTHIVAN TABLET should be carefully monitored throughout the treatment.
You can still infect other people while taking SYNTHIVAN TABLET . So, use necessary precautions to avoid infecting others.
SYNTHIVAN TABLET may cause abnormal liver function tests. So, regular monitoring of liver function is necessary while taking this medicine.

Disease/Condition Glossary

HIV infection: HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral agents.