Telista Plus 40 Tablet 15's

Written By Urvashi Bharti , MBBS

Reviewed By Sunny S , MBBS

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MRP ₹356

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About Telista Plus 40 Tablet

Telista Plus 40 Tablet is a combination medicine used to treat hypertension (high blood pressure) and hyperlipidemia (high cholesterol level). Additionally, Telista Plus 40 Tablet is used to reduce the risk of heart attack or stroke in adults. Hypertension is a medical condition in which the blood pressure is elevated persistently in the arteries without any known cause. Hyperlipidemia or dyslipidemia is the deposition of unhealthy levels of fats (lipids) in the blood.

Telista Plus 40 Tablet is a combination of two drugs, namely: Telmisartan (angiotensin receptor blocker) and Atorvastatin (cholesterol-lowering drugs). Telmisartan works by blocking the action of angiotensin II in the body that, causes the narrowing of blood vessels (arteries), leading to high blood pressure. Thereby relaxing and widening the blood vessels. Thus, lowers high blood pressure. Atorvastatin lowers the level of low-density lipoprotein (LDL) or bad cholesterol in the blood. Telista Plus 40 Tablet helps to decrease the production of cholesterol that may build up in the blood vessels (arteries) of the heart, brain, and other parts of the body.

Your doctor will advise you on how often you need to take Telista Plus 40 Tablet based on your medical condition. In a few cases, you may experience a sinus infection, dizziness, hyperglycemia (excess of glucose in the bloodstream), headache, blurred vision, constipation, nausea, diarrhoea, muscle spasms, and back pain. Most of these side effects of Telista Plus 40 Tablet do not require medical attention and gradually resolve over time. Consult your doctor immediately if you have yellowing eye/skin (jaundice), dark urine, or repeated unexplained muscular pain.

Avoid intake of potassium supplements with Telista Plus 40 Tablet as it may lead to high potassium levels in the blood, so the doctor may ask you to have a regular check of your potassium level. Do not consume alcohol with Telista Plus 40 Tablet as it may increase the risk of low blood pressure. Telista Plus 40 Tablet may cause a breakdown of skeletal muscle tissue, leading to kidney failure. This condition usually occurs in the elderly, people with kidney disease, and poorly controlled hypothyroidism (underactive thyroid). The efficiency of Telista Plus 40 Tablet can be increased by taking low fat or cholesterol-containing food and drinks, a low salt diet, and regular exercise.

Uses of Telista Plus 40 Tablet

High blood pressure (hypertension), Lowering of raised cholesterol, Prevention of heart attack and stroke

Directions for Use

Swallow Telista Plus 40 Tablet as a whole with water. Do not crush, chew, or break it.

Medicinal Benefits

Telista Plus 40 Tablet is a combination drug namely; Telmisartan (blood pressure-lowering agent) and Atorvastatin (cholesterol-lowering agent) primarily taken to prevent heart attack and stroke in people with heart problems. It also lowers the raised level of bad cholesterol (especially those at high risk of heart diseases). Telmisartan is an angiotensin receptor blocker (ARB) that lower increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and therefore helps lower high blood pressure. Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). Together Telista Plus 40 Tablet reduces the risk of heart attack and stroke.

Storage

Keep Telista Plus 40 Tablet out of the sight and reach of children.

Side effects of Telista Plus 40 Tablet

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Joint Pain

Here are the steps to manage Joint Pain caused by medication usage:

Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

Common Cold

Here are the steps to manage the medication-triggered Common Cold:

Inform your doctor about the common cold symptoms you're experiencing due to medication.
Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Gas Or Fart

Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:

Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Pain In Arm Or Leg

Eat fatty fish rich in omega-3 fatty acids to reduce inflammation.
Add whole grains such as brown rice, quinoa, and whole wheat bread to your diet for a nutritional boost.
Add nuts and seeds like almonds, walnuts, chia seeds for anti-inflammatory benefits.
Eat dark leafy greens like spinach, kale, collard greens for antioxidants.
Include berries like blueberries, strawberries, raspberries for anti-inflammatory properties.
Rest and take a break from usual activities.
Apply ice for 15-20 minutes, 3 times a day to reduce pain and inflammation.
Use compression with a stretchable bandage or wrap to lessen swelling and provide support.
Avoid strenuous activities and rest the affected area.
Try light stretching with gentle exercises to maintain flexibility.
Consider OTC pain medications like ibuprofen or acetaminophen but consult a doctor before taking any medication.

Drug Warnings

Telista Plus 40 Tablet should not be given to the people allergic to Telista Plus 40 Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. It should be used with caution in patients suffering from diabetes. Avoid intake of potassium supplements with Telista Plus 40 Tablet as it may lead to high potassium levels in the blood, so the doctor may ask you to have a regular check of your potassium level. Taking Telista Plus 40 Tablet with painkillers (like aspirin and ibuprofen) can increase the risk of kidney problems and reduced the efficiency of Telista Plus 40 Tablet . If you are taking or have taken in the last 7 days a medicine called fusidic acid for bacterial infection orally or by injection. Telista Plus 40 Tablet contains Atorvastatin, the combination of fusidic acid and Atorvastatin can lead to rhabdomyolysis (serious muscle problems). Telista Plus 40 Tablet may cause tiredness or dizziness in some people. Make sure you are not affected before driving. Do not consume alcohol with Telista Plus 40 Tablet as it may increase the risk of low blood pressure.

Drug-Drug Interactions

AtorvastatinPosaconazole

Critical

TelmisartanAliskiren

Critical

Drug-Drug Interactions

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AtorvastatinPosaconazole

Critical

How does the drug interact with Telista Plus 40 Tablet:
Taking Telista Plus 40 Tablet with Posaconazole can increase the blood levels of Telista Plus 40 Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Telista Plus 40 Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

TelmisartanAliskiren

Critical

How does the drug interact with Telista Plus 40 Tablet:
Co-administration of Aliskiren with Telista Plus 40 Tablet can increase the risk of hyperkalemia (high potassium levels in the blood).

How to manage the interaction:
Taking Telista Plus 40 Tablet with Aliskiren can possibly lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.

AtorvastatinRanolazine

Severe

How does the drug interact with Telista Plus 40 Tablet:
Co-administration of Telista Plus 40 Tablet with Ranolazine can possibly lead to elevated levels of Telista Plus 40 Tablet in blood.

How to manage the interaction:
Co-administration of Telista Plus 40 Tablet with Ranolazine can result in an interaction. It can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not discontinue the medications without consulting.

AtorvastatinColchicine

Severe

How does the drug interact with Telista Plus 40 Tablet:
coadministration of Telista Plus 40 Tablet with colchicine can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Telista Plus 40 Tablet with colchicine can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, diarrhea, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet, consult the doctor. Do not stop using any medications without talking to a doctor.

AtorvastatinLeflunomide

Severe

How does the drug interact with Telista Plus 40 Tablet:
When Telista Plus 40 Tablet and leflunomide are taken together it can increase the risk of liver problems.

How to manage the interaction:
Although taking Telista Plus 40 Tablet and leflunomide together can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

AtorvastatinNicotinic acid

Severe

How does the drug interact with Telista Plus 40 Tablet:
Combining Telista Plus 40 Tablet with nicotinic acid may raise the risk of rhabdomyolysis, (an uncommon illness that leads to the destruction of skeletal muscle tissue). If you are elderly or have preexisting kidney disease, you may be at higher risk. This interaction is only relevant if you are taking large doses of nicotinic acid to treat high cholesterol. It does not apply if you are taking nicotinic acid in nutritional supplement amounts.

How to manage the interaction:
Taking Telista Plus 40 Tablet and nicotinic acid together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you happen to experience, unexplained muscle pain, tenderness, weakness, fever, dark coloured urine, light coloured stools, you are advised to seek immediate medical attention. Do not discontinue any medications without consulting a doctor.

AtorvastatinTroleandomycin

Severe

How does the drug interact with Telista Plus 40 Tablet:
Using Telista Plus 40 Tablet together with troleandomycin may significantly increase the blood levels of Telista Plus 40 Tablet.

How to manage the interaction:
Taking Telista Plus 40 Tablet with Troleandomycin together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.

AtorvastatinFenofibrate

Severe

How does the drug interact with Telista Plus 40 Tablet:
Coadministration of Fenofibrate with Telista Plus 40 Tablet can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although taking Fenofibrate and Telista Plus 40 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.

AtorvastatinNefazodone

Severe

How does the drug interact with Telista Plus 40 Tablet:
Using Telista Plus 40 Tablet together with nefazodone may significantly increase the blood levels of Telista Plus 40 Tablet.

How to manage the interaction:
Taking Telista Plus 40 Tablet with Nefazodone together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.

AtorvastatinClarithromycin

Severe

How does the drug interact with Telista Plus 40 Tablet:
Co-administration of Telista Plus 40 Tablet with Clarithromycin possibly enhances Telista Plus 40 Tablet levels in the blood. This can raise the chance of side effects (liver damage and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Telista Plus 40 Tablet if prescribed by the doctor. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

ATORVASTATIN-10MG+TELMISARTAN-40MGPotassium rich foods, Grapefruit and Grapefruit Juice

Moderate

Drug-Food Interactions

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ATORVASTATIN-10MG+TELMISARTAN-40MGPotassium rich foods, Grapefruit and Grapefruit Juice

Moderate

Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Grapefruit, Grapefruit Juice

How to manage the interaction:
Taking potassium rich food, grapefruit and grape juice while on the treatment with Telmisartan and Atorvastatin can increase the levels of potassium salt in blood and other side effects like nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, confusion, or slow or rapid heartbeat. Avoid or limit taking potassium rich food, grapefruit and grape juice while on the treatment with Telmisartan and Atorvastatin.

Diet & Lifestyle Advise

Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short span of time. Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and low in red meat and most dairy.
Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants that help to lower LDL
Minimize the intake of added sugar. The American Heart Association (ADA) recommends, one should not eat more than 100 calories (25 grams) of added sugar for women and children, and no more than 150 calories (37.5 grams) for men every day.
American Heart Association recommends the intake of sodium chloride (table salt) should not exceed more than 2,300 mg per day as part of a healthy eating pattern.
Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
Try aromatherapy, yoga, meditation to help relax your body and mind.
Chronic stress may also cause high blood pressure. Therefore, avoid stress by changing your expectations, the way you react in certain situations, and making time for yourself to do activities that you enjoy.
As a precautionary measure, do not consume alcohol and quit smoking.

Side Effects of Telista Plus 40 Tablet

Dizziness
Stuffy nose, sinus pain
Nausea
Stomach pain
Constipation
Muscle pain
Hypotension (low blood pressure)
Hyperglycemia (Increased glucose level in blood)

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

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Author Details

Written By

Urvashi Bharti

MBBS

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:32 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Telista Plus 40 Tablet work?

Telista Plus 40 Tablet is composed of two medicines, namely: Telmisartan and Atorvastatin. Telmisartan is an angiotensin receptor blocker (ARB), that works by relaxing the blood vessels and making the heart more efficient at pumping blood throughout the body. Atorvastatin lowers raised fat/cholesterol. Thus, together Telista Plus 40 Tablet reduces the risk of heart attack and stroke.

Can I stop taking Telista Plus 40 Tablet when my blood pressure is under control?

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend to discontinue it.

Can Telista Plus 40 Tablet be taken for years?

Usually, Telista Plus 40 Tablet is prescribed for a long term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.

Is there any lifestyle help for reducing bad cholesterol in our blood?

Increase your daily diet with fiber, fruits, vegetables, whole grains, and fish, and cut saturated fat as well. Stop smoking and drinking and try to work out every day as well.

What foods are to be avoided while taking Telista Plus 40 Tablet ?

Telista Plus 40 Tablet contains 'Telmisartan' which may increase potassium levels in the blood (hyperkalemia). Therefore, it is recommended to avoid the intake of potassium supplements and foods that are rich in potassium like coconut water, bananas, and broccoli.

Is Telista Plus 40 Tablet safe to use during pregnancy?

No, Telista Plus 40 Tablet are not recommended for use during pregnancy especially in the second and third trimesters as it may harm the developing baby. Therefore, if you are pregnant or planning for pregnancy, please inform your doctor before taking Telista Plus 40 Tablet .

Will taking Telista Plus 40 Tablet increase my risk of diabetes?

Telista Plus 40 Tablet contains atorvastatin which can raise your blood sugar a little. If you already have type 2 diabetes please consult your doctor. Your doctor may adjust the dosage of Telista Plus 40 Tablet .

Drug-Drug Interactions Checker List

BENAZEPRIL
METOPROLOL
RAMIPRIL
ALISKIREN
VERAMAPIL
SIMVASTATIN
LISINOPRIL
AMILORIDE
AMLODIPINE
DILTIAZEM
GEMFIBROZIL
AZILSARTAN MEDOXOMIL
CLOFIBRATE
FENOFIBRATE
COLESTIPOL
EZETIMIBE
DIGOXIN
WARFARIN
TRIMETHOPRIM
ERYTHROMYCIN
CLARITHROMYCIN
TELITHROMYCIN
FUSIDIC ACID
RIFAMPICIN
KETOCONAZOLE
ITRACONAZOLE
VORICONAZOLE
FLUCONAZOLE
POSACONAZOLE
RITONAVIR
LOPINAVIR
ATAZANAVIR
INDINAVIR
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CARBAMAZEPINE
PHENYTOIN
PHENOBARBITAL
PRIMIDONE
CYCLOSPORINE
TACROLIMUS
IBUPROFEN
ASPIRIN

Special Advise

Monitor your blood pressure regularly and if you notice any fluctuations, please consult a doctor.

Disease/Condition Glossary

Hypertension: Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

Hyperlipidemia: High cholesterol, known as hyperlipidemia or dyslipidemia, occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high cholesterol level in the blood, your arteries get narrowed and clogged that finally contributes to heart diseases like stroke and heart attack. Eating high-fat or high-cholesterol containing food/drinks and genetic factors are the primary causes of high cholesterol.