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Reviewed By Sunny S , MBBS

About Tide E 20 Tablet Combikit

Tide E 20 Tablet Combikit belongs to a class of medicine called 'diuretics' (water pills) primarily used to remove excess water from the body. It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure) due to oedema (fluid retention). Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular heart pumping). Leg swelling is the main characteristic of oedema, accompanied by shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia) and swelling in other hands or abdomen areas.

Tide E 20 Tablet Combikit is a combination of medications containing Eplerenone and Torsemide, which are prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure and hepatic cirrhosis (chronic liver damage). Tide E 20 Tablet Combikit works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain) in the future.

Take Tide E 20 Tablet Combikit as prescribed by your doctor. Depending upon your medical condition, you are advised to take Tide E 20 Tablet Combikit for as long as your doctor has prescribed it for you. In some cases, you may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid. Most of these side effects of Tide E 20 Tablet Combikit do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Tide E 20 Tablet Combikit of your own, as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Inform your doctor if you are suffering from kidney, liver or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Tide E 20 Tablet Combikit can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to the Tide E 20 Tablet Combikit. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

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Non returnable*
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Online payment accepted

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Tide E 20 Tablet Combikit

Oedema (fluid overload)

Medicinal Benefits

Tide E 20 Tablet Combikit is primarily used to remove excess water from the body. It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure) due to oedema (fluid retention). Tide E 20 Tablet Combikit is a combination of medications containing Eplerenone and Torsemide. Both Eplerenone and Torsemide are diuretics and are prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure and hepatic cirrhosis (chronic liver damage). Tide E 20 Tablet Combikit works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain) in the future.

Side Effects of Tide E 20 Tablet Combikit

  • Dehydration
  • Electrolyte disturbances (calcium, magnesium, and sodium)
  • Constipation
  • Itching
  • Increased uric acid

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Tide E 20 Tablet Combikit should not be given to the people allergic to Tide E 20 Tablet Combikit, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, pregnant women, or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Tide E 20 Tablet Combikit can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you are taking Tide E 20 Tablet Combikit and breastfeeding. Dehydration with electrolyte and acid-base disturbances must be corrected before using Tide E 20 Tablet Combikit. Do not take any extra potassium supplements or potassium-rich foods such as bananas and broccoli with Tide E 20 Tablet Combikit. It may lead to an excessive increase in blood potassium levels (hyperkalemia). Please take Tide E 20 Tablet Combikit at least 4 hours before sleeping to avoid frequent urination at night.

Therapeutic Class

ANTI- HYPERTENSIVES

Drug-Drug Interactions

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EplerenonePosaconazole
Critical
EplerenoneNefazodone
Critical

Drug-Drug Interactions

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EplerenonePosaconazole
Critical
How does the drug interact with Tide E 20 Tablet Combikit:
Coadministration of posaconazole with Tide E 20 Tablet Combikit can increase the blood levels of Tide E 20 Tablet Combikit. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).

How to manage the interaction:
Although there is an interaction between posaconazole and Tide E 20 Tablet Combikit, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EplerenoneNefazodone
Critical
How does the drug interact with Tide E 20 Tablet Combikit:
Coadministration of Nefazodone with Tide E 20 Tablet Combikit can increase the levels of Tide E 20 Tablet Combikit in the body.

How to manage the interaction:
Taking Nefazodone with Tide E 20 Tablet Combikit together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without a doctor's advice.
EplerenoneClarithromycin
Critical
How does the drug interact with Tide E 20 Tablet Combikit:
Co-administration of Tide E 20 Tablet Combikit and Clarithromycin may significantly increase the blood levels and effects of Tide E 20 Tablet Combikit.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Clarithromycin with Tide E 20 Tablet Combikit is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
EplerenoneSpironolactone
Critical
How does the drug interact with Tide E 20 Tablet Combikit:
Combining Tide E 20 Tablet Combikit with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between spironolactone and Tide E 20 Tablet Combikit, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenonePotassium citrate
Critical
How does the drug interact with Tide E 20 Tablet Combikit:
Taking Tide E 20 Tablet Combikit with Potassium citrate may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Tide E 20 Tablet Combikit, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenoneSaquinavir
Critical
How does the drug interact with Tide E 20 Tablet Combikit:
Co-administration of EPELENONE and SAQUINAVIR may significantly increase the blood levels and side effects of Tide E 20 Tablet Combikit. This can increase the risk of serious side effects like high blood potassium, which in severe cases can lead to kidney failure, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Taking saquinavir and Tide E 20 Tablet Combikit together is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the doctor's advice.
EplerenonePotassium chloride
Critical
How does the drug interact with Tide E 20 Tablet Combikit:
Using Tide E 20 Tablet Combikit together with Potassium chloride may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking potassium chloride with Tide E 20 Tablet Combikit is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenoneRitonavir
Critical
How does the drug interact with Tide E 20 Tablet Combikit:
Co-administration of Tide E 20 Tablet Combikit and Ritonavir may significantly increase the blood levels of Tide E 20 Tablet Combikit.

How to manage the interaction:
Taking Ritonavir and Tide E 20 Tablet Combikit together is not recommended as it can lead to an interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
EplerenonePotassium iodide
Critical
How does the drug interact with Tide E 20 Tablet Combikit:
Combining Tide E 20 Tablet Combikit with Potassium iodide may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium iodide and Tide E 20 Tablet Combikit, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenoneItraconazole
Critical
How does the drug interact with Tide E 20 Tablet Combikit:
The blood levels and effects of Tide E 20 Tablet Combikit may be greatly increased when combined with itraconazole.

How to manage the interaction:
Although there is a possible interaction between Tide E 20 Tablet Combikit and Itraconazole, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ROSUVASTATIN
  • ATORVASTATIN
  • ASPIRIN
  • WARFARIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • CYCLOSPORINE
  • IBUPROFEN

Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid the consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • When possible, elevate your legs or the swollen area on a chair or pillows.
  • Avoid standing or sitting for extended periods of time.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Special Advise

  • Treatment with Tide E 20 Tablet Combikit requires regular monitoring of serum potassium, sodium and creatinine levels.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Regular monitoring of uric acid in patients with gouty arthritis.

Disease/Condition Glossary

Oedema: Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular pumping of the heart). The main characteristics of oedema are leg swelling,  shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia) and swelling in other hands or abdomen areas.

Tide E 20 Tablet Combikit Substitute

Substitutes safety advice
  • Dytor E 20 Combikit

    by AYUR

    15.87per tablet
  • Eptus-T 20 Tablet 10's

    by AYUR

    33.93per tablet
  • Epnone-T20 Combikit Tablet 20's

    by AYUR

    12.51per tablet
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