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TILSTIGMIN 0.5MG INJECTION 1ML

TILSTIGMIN 0.5MG INJECTION 1ML

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Prescription drug
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About TILSTIGMIN 0.5MG INJECTION 1ML

TILSTIGMIN 0.5MG INJECTION 1ML belongs to a group of medicines called 'anticholinesterase agents/acetylcholinesterase inhibitors,' primarily used to treat myasthenia gravis and to reverse the effects of anaesthesia medicines used during surgery. TILSTIGMIN 0.5MG INJECTION 1ML is also used to treat paralytic ileus (a rare form of constipation) and postoperative urinary retention.

TILSTIGMIN 0.5MG INJECTION 1ML contains 'Neostigmine.' It increases levels of a neurotransmitter called acetylcholine by stopping the excess cholinesterase activity (an enzyme required to break down acetylcholine) involved in communication between nerve impulses and muscle movements. Neurotransmitters are chemical messengers that transmit the message from one nerve cell to another nerve cell, muscle cell, or gland cell. Thus TILSTIGMIN 0.5MG INJECTION 1ML helps in proper muscle functioning and prevents muscle weakness.

TILSTIGMIN 0.5MG INJECTION 1ML will be administered by a health care professional, do not self-administer. Your dose and duration will be based on the severity of your medical condition. In some cases, you may experience common side effects, such as nausea, vomiting, slow heartbeat, abdominal cramp, diarrhoea, increased saliva production, dizziness, headache, trouble sleeping, and dry mouth. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor before using this medicine if you have a history of liver, heart or kidney diseases, asthma, stomach ulcer, fits, Parkinson's disease, overactive thyroid, or vagotonia/irritability of the vagus nerve (connects to the abdomen from the brain) that causes excess bowel contractions. Let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before starting TILSTIGMIN 0.5MG INJECTION 1ML . Avoid consuming alcohol during the course to prevent unwanted side effects. TILSTIGMIN 0.5MG INJECTION 1ML can be given to children if prescribed by the doctor; the dose depends on the child's age and weight.

Uses of TILSTIGMIN 0.5MG INJECTION 1ML

Myasthenia gravis, paralytic ileus, and post-operative urinary retention.

Medicinal Benefits

TILSTIGMIN 0.5MG INJECTION 1ML belongs to the group of medicines called 'anticholinesterase agents/cholinesterase inhibitors and is used to treat myasthenia gravis (muscle weakness). TILSTIGMIN 0.5MG INJECTION 1ML contains 'Neostigmine'. It stops the excessive activity of cholinesterase, helping the muscles work properly. Additionally, TILSTIGMIN 0.5MG INJECTION 1ML is used to treat paralytic ileus (a rare form of constipation) and postoperative urinary retention. It reverses the effects of neuromuscular blocking agents/anaesthesia medicines used during surgery. TILSTIGMIN 0.5MG INJECTION 1ML affects the chemicals in the body, which are involved in communication between nerve impulses and muscle movements. Thereby, TILSTIGMIN 0.5MG INJECTION 1ML treats muscle-associated disorders by improving muscle strength.

Directions for Use

A healthcare professional will administer it; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TILSTIGMIN 0.5MG INJECTION 1ML

  • Nausea
  • Vomiting
  • Slow heartbeat
  • Abdominal cramp
  • Diarrhoea
  • Increased saliva production
  • Dizziness
  • Headache
  • Trouble sleeping
  • Dry mouth

Drug Warnings

Let your doctor know if you use any other medicines or supplements before using TILSTIGMIN 0.5MG INJECTION 1ML . Brief your medical history if you have any liver or kidney diseases, heart diseases (coronary artery disease, irregular heartbeat), asthma, stomach ulcer, fits, urination problems, Parkinson's disease, overactive thyroid, and vagotonia before starting TILSTIGMIN 0.5MG INJECTION 1ML . Please consult your doctor if you are pregnant, planning to conceive or are a breastfeeding mother. Avoid consuming alcohol to get the maximum benefits of the medicine and prevent the disease's aggravation. Drive or operate machinery only when you are alert and focused during the course.

Drug Interactions

Drug-Drug Interaction: TILSTIGMIN 0.5MG INJECTION 1ML may interact with anaesthetics (halothane, cyclopropane), muscle relaxants (succinylcholine, suxamethonium), and antibiotics (neomycin, streptomycin).

Drug-Food Interaction: Avoid alcohol intake while being treated with TILSTIGMIN 0.5MG INJECTION 1ML .

Drug-Disease Interaction: Let your doctor know if you have asthma, bradycardia (slow heart rate), bronchospasm, fits, overactive thyroid, stomach ulcer, coronary artery disease, urination problems, Parkinson's disease, or irritability of vagus nerve before starting TILSTIGMIN 0.5MG INJECTION 1ML .

Drug-Drug Interactions Checker List

  • HALOTHANE
  • CYCLOPROPANE
  • SUCCINYLCHOLINE
  • SUXAMETHONIUM
  • NEOMYCIN
  • STREPTOMYCIN

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat warm meals rather than hot meals, as heat aggravates the disease.
  • Try sipping a cold drink while having hot or warm meals.
  • Avoid foods that require a lot of chewing, like tough meats.
  • Exercise regularly to keep your muscles strong
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.

Special Advise

TILSTIGMIN 0.5MG INJECTION 1ML might interfere with the effects of skeletal muscle relaxants used in the surgery. 

Disease/Condition Glossary

Myasthenia gravis: It is an autoimmune neuromuscular disease that causes skeletal muscle weakness. The immune system mistakenly attacks its healthy tissues, damaging the neuromuscular membrane. This reduces the effect of acetylcholine, a neurotransmitter that plays a major role in the communication between nerve cells and muscles. Myasthenia gravis occurs when the communication between nerve cells and muscles becomes impaired. This prevents muscle contractions, thereby leading to muscle weakness. The most affected muscles are those of the face and eyes. Symptoms of myasthenia gravis include double vision, drooping eyelids, difficulty chewing or swallowing, weakness, problems with lifting objects, and trouble talking and walking.

Paralytic ileus: It is a condition in which there is obstruction of the intestine due to paralysis of intestinal muscles. This prevents the passage of food and leads to its accumulation in the intestine. Paralytic ileus occurs due to malfunctioning nerves and muscles in the intestine, thereby impairing digestive movement. 

Country of origin

India

Manufacturer/Marketer address

Tablets (India) Limited, ?Jhaver Centre?, 72 Marshalls Road, Chennai 600 008.
Other Info - TIL0003

FAQs

TILSTIGMIN 0.5MG INJECTION 1ML works by stopping the excessive cholinesterase activity (an enzyme necessary for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, TILSTIGMIN 0.5MG INJECTION 1ML helps in proper muscle functioning and prevents muscle weakness.
TILSTIGMIN 0.5MG INJECTION 1ML should be used with caution in the medical history of liver or kidney diseases, heart diseases (coronary artery disease, irregular heartbeat), peritonitis (inflammation of the membrane lining the abdominal wall and covering the abdominal organs), stomach ulcer, asthma, fits, urination problems, Parkinson's disease, overactive thyroid (hypothyroidism), and vagotonia. Please let your doctor know if you have any other medical problems before starting TILSTIGMIN 0.5MG INJECTION 1ML .
Generally, women aged 20 to 40 and men aged 50 to 80 are affected by myasthenia gravis. High-risk factors for developing this disease include autoimmune diseases like rheumatoid arthritis and lupus, infections, surgical procedures, thyroid disease, and medications for malaria, heart arrhythmias and cancer.
Diabetes may trigger a stronger immune response due to an abnormal rise in blood sugar levels. This may further lead to the worsening of the myasthenia gravis.

Disclaimer

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Alcohol

Caution

Avoid consuming alcohol during the course with TILSTIGMIN 0.5MG INJECTION 1ML to prevent any undesirable side effects.

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Pregnancy

Caution

There is limited information on how TILSTIGMIN 0.5MG INJECTION 1ML affects pregnancy. If you are pregnant or planning to conceive, inform your doctor before taking TILSTIGMIN 0.5MG INJECTION 1ML .

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Breast Feeding

Caution

It is not known if Neostigmine is excreted into breast milk. Please inform your doctor before taking TILSTIGMIN 0.5MG INJECTION 1ML if you are a breastfeeding mother.

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Driving

Caution

Neostigmine may make you feel dizzy and affect your ability to drive. It is advised not to drive or operate machinery while being treated with TILSTIGMIN 0.5MG INJECTION 1ML if you are not mentally alert and focused.

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Liver

Caution

Please inform your doctor before receiving TILSTIGMIN 0.5MG INJECTION 1ML if you have liver problems.

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Kidney

Caution

Please inform your doctor before receiving TILSTIGMIN 0.5MG INJECTION 1ML if you have kidney disease.

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Children

Caution

TILSTIGMIN 0.5MG INJECTION 1ML is recommended in children below 12 years of age only when prescribed by the doctor. The dosage depends on the child's age, weight and condition.

Author Details

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