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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
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Not Returnable

About Tispas 20mg/50mg/325mg Tablet

Tispas 20mg/50mg/325mg Tablet is a combination medicine used to relieve pain and discomfort associated with intestinal colic, biliary colic, renal colic and spasmodic dysmenorrhoea (menstrual cramps). Additionally, Tispas 20mg/50mg/325mg Tablet is also used to reduce pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, backache, strain, and sprain. 
 
Tispas 20mg/50mg/325mg Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol and Dicyclomine. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Together, Tispas 20mg/50mg/325mg Tablet helps in providing relief from pain.
 
You are advised to take Tispas 20mg/50mg/325mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Tispas 20mg/50mg/325mg Tablet may cause common side-effects such as nausea, vomiting, heartburn, dizziness, and diarrhoea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Tispas 20mg/50mg/325mg Tablet may cause dizziness, so drive with caution. Tispas 20mg/50mg/325mg Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Tispas 20mg/50mg/325mg Tablet as it could lead to increased dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Tispas 20mg/50mg/325mg Tablet

Abdominal pain, cramps, muscle and joint pain.

Directions for Use

Swallow Tispas 20mg/50mg/325mg Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Tispas 20mg/50mg/325mg Tablet is a combination of three drugs, namely: Diclofenac (NSAID), Paracetamol (Analgesic) and Dicyclomine (Anti-cholinergic). Tispas 20mg/50mg/325mg Tablet is used to relieve pain and discomfort associated with intestinal colic, biliary colic, renal colic and spasmodic dysmenorrhoea (menstrual cramps). Additionally, Tispas 20mg/50mg/325mg Tablet is also used to reduce pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, backache, strain, and sprain. Diclofenac and Paracetamol work by blocking the effect of chemical messengers known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Together, Tispas 20mg/50mg/325mg Tablet helps in providing relief from abdominal spasms.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Tispas 20mg/50mg/325mg Tablet if you are allergic to any of its contents; if you have/had severe heart problems, stomach ulcer or perforation, and bleeding problems such as bleeding from the stomach. Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, bypass surgery, heart attack, blood circulation problems, inflammation of intestines, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Tispas 20mg/50mg/325mg Tablet may cause dizziness, so drive only if you are alert. Tispas 20mg/50mg/325mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Tispas 20mg/50mg/325mg Tablet as it could lead to increased dizziness and can increase the risk of stomach bleeding. Stop taking Tispas 20mg/50mg/325mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Tispas 20mg/50mg/325mg Tablet unless prescribed. 

Drug-Drug Interactions

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DicyclominePotassium citrate
Critical

Drug-Drug Interactions

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How does the drug interact with Tispas 20mg/50mg/325mg Tablet:
Co-administration of Tispas 20mg/50mg/325mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Tispas 20mg/50mg/325mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DicyclominePotassium citrate
Critical
How does the drug interact with Tispas 20mg/50mg/325mg Tablet:
Taking Tispas 20mg/50mg/325mg Tablet and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Tispas 20mg/50mg/325mg Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Tispas 20mg/50mg/325mg Tablet:
Co-administration of Tispas 20mg/50mg/325mg Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Tispas 20mg/50mg/325mg Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
DicyclominePramlintide
Critical
How does the drug interact with Tispas 20mg/50mg/325mg Tablet:
Co-administration of Pramlintide with Tispas 20mg/50mg/325mg Tablet can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking Tispas 20mg/50mg/325mg Tablet with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Tispas 20mg/50mg/325mg Tablet:
Concomitant use of Tispas 20mg/50mg/325mg Tablet with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking Tispas 20mg/50mg/325mg Tablet with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Tispas 20mg/50mg/325mg Tablet:
Co-administration of Tispas 20mg/50mg/325mg Tablet and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of Tispas 20mg/50mg/325mg Tablet and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tispas 20mg/50mg/325mg Tablet:
Co-administration of Tispas 20mg/50mg/325mg Tablet with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Tispas 20mg/50mg/325mg Tablet and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacPonatinib
Severe
How does the drug interact with Tispas 20mg/50mg/325mg Tablet:
Taking Tispas 20mg/50mg/325mg Tablet with Ponatinib can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Tispas 20mg/50mg/325mg Tablet and Ponatinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tispas 20mg/50mg/325mg Tablet:
Co-administration of Tispas 20mg/50mg/325mg Tablet and Apixaban may raise the risk of stomach bleeding.

How to manage the interaction:
Although there is a interaction between Tispas 20mg/50mg/325mg Tablet and apixaban, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Tispas 20mg/50mg/325mg Tablet:
Co-administration use of Tispas 20mg/50mg/325mg Tablet with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Tispas 20mg/50mg/325mg Tablet may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Tispas 20mg/50mg/325mg Tablet contains Diclofenac, Paracetamol and Dicyclomine. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause inflammation at the injured or damaged site. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Together, Tispas 20mg/50mg/325mg Tablet helps in providing relief from pain.

Diarrhoea might be a side-effect of Tispas 20mg/50mg/325mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.

Do not take any other pain killer medicines along with Tispas 20mg/50mg/325mg Tablet unless prescribed as it might lead to unpleasant side-effects and can increase the risk of stomach bleeding associated with NSAIDs.

Dry mouth could be a side-effect of Tispas 20mg/50mg/325mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Tispas 20mg/50mg/325mg Tablet should be taken for longer durations only if prescribed by the doctor. Avoid taking Tispas 20mg/50mg/325mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding.

Tispas 20mg/50mg/325mg Tablet may be used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods and menstrual cramps. Take Tispas 20mg/50mg/325mg Tablet only as prescribed, and do not overdose.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • METOPROLOL
  • ASPIRIN
  • HYDROCODONE
  • DULOXETINE

Disease/Condition Glossary

Abdominal pain and cramps: Abdominal pain occurs between the chest and pelvic region, generally known as stomach or tummy pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. The common causes of abdominal pain include inflammation, infections, intestinal disorders and obstruction/blockage. Abdominal pain could be generalised, localised, cramps or colicky pain.

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons, and nerves. It could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure or injury to the bones, joints, tendons, muscles and ligaments. Symptoms of musculoskeletal pain include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, and soreness.

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