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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
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Manufacturer/Marketer :

Meridian Medicare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Zodol 20mg/50mg/325mg Tablet

Zodol 20mg/50mg/325mg Tablet is a combination medicine used to relieve pain and discomfort associated with intestinal colic, biliary colic, renal colic and spasmodic dysmenorrhoea (menstrual cramps). Additionally, Zodol 20mg/50mg/325mg Tablet is also used to reduce pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, backache, strain, and sprain. 
 
Zodol 20mg/50mg/325mg Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol and Dicyclomine. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Together, Zodol 20mg/50mg/325mg Tablet helps in providing relief from pain.
 
You are advised to take Zodol 20mg/50mg/325mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Zodol 20mg/50mg/325mg Tablet may cause common side-effects such as nausea, vomiting, heartburn, dizziness, and diarrhoea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Zodol 20mg/50mg/325mg Tablet may cause dizziness, so drive with caution. Zodol 20mg/50mg/325mg Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Zodol 20mg/50mg/325mg Tablet as it could lead to increased dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Zodol 20mg/50mg/325mg Tablet

Abdominal pain, cramps, muscle and joint pain.

Directions for Use

Swallow Zodol 20mg/50mg/325mg Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Zodol 20mg/50mg/325mg Tablet is a combination of three drugs, namely: Diclofenac (NSAID), Paracetamol (Analgesic) and Dicyclomine (Anti-cholinergic). Zodol 20mg/50mg/325mg Tablet is used to relieve pain and discomfort associated with intestinal colic, biliary colic, renal colic and spasmodic dysmenorrhoea (menstrual cramps). Additionally, Zodol 20mg/50mg/325mg Tablet is also used to reduce pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, backache, strain, and sprain. Diclofenac and Paracetamol work by blocking the effect of chemical messengers known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Together, Zodol 20mg/50mg/325mg Tablet helps in providing relief from abdominal spasms.

Storage

Keep Zodol 20mg/50mg/325mg Tablet out of reach and sight of children.

Drug Warnings

Do not take Zodol 20mg/50mg/325mg Tablet if you are allergic to any of its contents; if you have/had severe heart problems, stomach ulcer or perforation, and bleeding problems such as bleeding from the stomach. Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, bypass surgery, heart attack, blood circulation problems, inflammation of intestines, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Zodol 20mg/50mg/325mg Tablet may cause dizziness, so drive only if you are alert. Zodol 20mg/50mg/325mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Zodol 20mg/50mg/325mg Tablet as it could lead to increased dizziness and can increase the risk of stomach bleeding. Stop taking Zodol 20mg/50mg/325mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Zodol 20mg/50mg/325mg Tablet unless prescribed. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zodol 20mg/50mg/325mg Tablet:
Co-administration of Zodol 20mg/50mg/325mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Zodol 20mg/50mg/325mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Zodol 20mg/50mg/325mg Tablet:
Co-administration of Zodol 20mg/50mg/325mg Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Zodol 20mg/50mg/325mg Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
DicyclominePramlintide
Critical
How does the drug interact with Zodol 20mg/50mg/325mg Tablet:
Co-administration of Pramlintide with Zodol 20mg/50mg/325mg Tablet can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking Zodol 20mg/50mg/325mg Tablet with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium citrate
Critical
How does the drug interact with Zodol 20mg/50mg/325mg Tablet:
Taking Zodol 20mg/50mg/325mg Tablet and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Zodol 20mg/50mg/325mg Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DiclofenacValdecoxib
Severe
How does the drug interact with Zodol 20mg/50mg/325mg Tablet:
Taking Valdecoxib with Zodol 20mg/50mg/325mg Tablet may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Zodol 20mg/50mg/325mg Tablet and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
How does the drug interact with Zodol 20mg/50mg/325mg Tablet:
Co-administration of Zodol 20mg/50mg/325mg Tablet with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Zodol 20mg/50mg/325mg Tablet and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
DiclofenacMipomersen
Severe
How does the drug interact with Zodol 20mg/50mg/325mg Tablet:
Co-administration of Zodol 20mg/50mg/325mg Tablet with Mipomersen may cause liver problems.

How to manage the interaction:
Co-administration of Zodol 20mg/50mg/325mg Tablet and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DiclofenacSulindac
Severe
How does the drug interact with Zodol 20mg/50mg/325mg Tablet:
Co-administration of Zodol 20mg/50mg/325mg Tablet and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Zodol 20mg/50mg/325mg Tablet and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zodol 20mg/50mg/325mg Tablet:
Co-administration of Zodol 20mg/50mg/325mg Tablet and tenofovir alafenamide may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between Zodol 20mg/50mg/325mg Tablet and Tenofovir alafenamide but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
How does the drug interact with Zodol 20mg/50mg/325mg Tablet:
Taking Zodol 20mg/50mg/325mg Tablet with Ibrutinib can increase the risk of bleeding tendencies.

How to manage the interaction:
There may be a possible interaction between Zodol 20mg/50mg/325mg Tablet and Ibrutinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Side Effects of Zodol 20mg/50mg/325mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Heartburn
  • Dizziness

Habit Forming

No

Therapeutic Class

ANALGESICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zodol 20mg/50mg/325mg Tablet contains Diclofenac, Paracetamol and Dicyclomine. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause inflammation at the injured or damaged site. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Together, Zodol 20mg/50mg/325mg Tablet helps in providing relief from pain.

Diarrhoea might be a side-effect of Zodol 20mg/50mg/325mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.

Do not take any other pain killer medicines along with Zodol 20mg/50mg/325mg Tablet unless prescribed as it might lead to unpleasant side-effects and can increase the risk of stomach bleeding associated with NSAIDs.

Dry mouth could be a side-effect of Zodol 20mg/50mg/325mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Zodol 20mg/50mg/325mg Tablet should be taken for longer durations only if prescribed by the doctor. Avoid taking Zodol 20mg/50mg/325mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding.

Zodol 20mg/50mg/325mg Tablet may be used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods and menstrual cramps. Take Zodol 20mg/50mg/325mg Tablet only as prescribed, and do not overdose.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • METOPROLOL
  • ASPIRIN
  • HYDROCODONE
  • DULOXETINE

Disease/Condition Glossary

Abdominal pain and cramps: Abdominal pain occurs between the chest and pelvic region, generally known as stomach or tummy pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. The common causes of abdominal pain include inflammation, infections, intestinal disorders and obstruction/blockage. Abdominal pain could be generalised, localised, cramps or colicky pain.

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons, and nerves. It could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure or injury to the bones, joints, tendons, muscles and ligaments. Symptoms of musculoskeletal pain include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, and soreness.

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zodol 20mg/50mg/325mg Tablet as it may increase dizziness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Zodol 20mg/50mg/325mg Tablet; your doctor will decide whether Zodol 20mg/50mg/325mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Zodol 20mg/50mg/325mg Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Zodol 20mg/50mg/325mg Tablet should not be given to children as the safety and effectiveness were not established.

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