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  3. Tobamist Respules 5X5 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

TOBRAMYCIN-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Inhalation

Expires on or after :

Return Policy :

Not Returnable

About Tobamist Respules 5X5 ml

Tobamist Respules 5X5 ml belongs to the class of aminoglycoside antibiotics. Tobamist Respules 5X5 ml is used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients aged six years and older. Pseudomonas aeruginosa is a type of bacteria that can cause lung or chest infections, especially in people who already have a lung disease (cystic fibrosis) or an issue with their immune system.

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights the infection in your lungs by interfering with protein synthesis in Pseudomonas bacterial cell and helps you breathe better.

Use the Tobamist Respules 5X5 ml as prescribed by your doctor. Sometimes, you may experience certain common side effects, such as runny or stuffy nose, sneezing, voice alteration (hoarseness), discolouration of the substance you cough up (sputum), worsening of lung function test results, feeling unwell, muscle pain and voice alteration with sore throat and difficulty swallowing (laryngitis). Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not use Tobamist Respules 5X5 ml if you are allergic to any of its components or other aminoglycoside antibiotics. Do not use the Tobamist Respules 5X5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Tobamist Respules 5X5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Tobamist Respules 5X5 ml is not recommended to be used in children under the age of six.

Uses of Tobamist Respules 5X5 ml

Chest infections (Pseudomonas aeruginosa infection)

Directions for Use

Check the label for directions before using the Tobamist Respules 5X5 ml. It is for inhalation only. Do not swallow the respules. Use it in the dose and for the duration advised by your doctor.

Key Benefits

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tobamist Respules 5X5 ml
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid smoking and intake of any tobacco products as it worsens lung disorders.
  • Get a physical examination, follow your doctor's instructions, and get required vaccinations.
  • Be physically active and eat healthy food.
  • Prefer practising yoga and meditation to reduce stress and anxiety.
  • Practice good hygiene and stay away from places where air pollution is high.

Drug Warnings

Do not use Tobamist Respules 5X5 ml if you are allergic to any of the components or other aminoglycoside antibiotics (neomycin, paromomycin, kanamycin). Do not use the Tobamist Respules 5X5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Tobamist Respules 5X5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Children and adolescents aged six and up are eligible to use Tobamist Respules 5X5 ml. Tobamist Respules 5X5 ml should not be given to children under the age of six. Before taking the Tobamist Respules 5X5 ml, notify your doctor about your medical history and other medications you are now taking to rule out any potential adverse effects or interactions.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tobamist Respules 5X5 ml:
Coadministration of cidofovir with Tobamist Respules 5X5 ml can cause kidney problems.

How to manage the interaction:
Taking Tobamist Respules 5X5 ml with Cidofovir is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Co-administration of Tobamist Respules 5X5 ml with torasemide increases the risk of toxicity.

How to manage the interaction:
Although taking Tobamist Respules 5X5 ml and torasemide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as blurred vision, dry mouth, dry skin, frequent urination, nausea, and stomach pain, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Coadministration of Tobamist Respules 5X5 ml with Sirolimus can cause an increased risk or severity of kidney problems.

How to manage the interaction:
Although taking Sirolimus and Tobamist Respules 5X5 ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Tobamist Respules 5X5 ml:
Taking magnesium sulfate with Tobamist Respules 5X5 ml can increase the risk of muscle weakness.

How to manage the interaction:
Although taking Magnesium sulfate and Tobamist Respules 5X5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as muscle weakness and breathing difficulties consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobamist Respules 5X5 ml:
Using Atracurium with Tobamist Respules 5X5 ml can increase the risk of respiratory depression (breathing disorder).

How to manage the interaction:
Although there is a interaction between Tobamist Respules 5X5 ml and Atracurium, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to your doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Taking deferasirox with Tobamist Respules 5X5 ml may increase the risk of kidney problems.

How to manage the interaction:
Taking Tobamist Respules 5X5 ml with Deferasirox together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Using Botulinum toxin and Tobamist Respules 5X5 ml together may increase the risk of side effects.

How to manage the interaction:
Although taking Botulinum toxin and Tobamist Respules 5X5 ml can cause an interaction, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience excessive muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Using Vecuronium with Tobamist Respules 5X5 ml can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Co-administration of Tobamist Respules 5X5 ml with Vecuronium can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Using Tobamist Respules 5X5 ml together with everolimus can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Everolimus and Tobamist Respules 5X5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience sudden weight gain, feeling out of breath, or having kidney problems. If you experience nausea, vomiting, loss of appetite, weight loss, swelling, muscle cramps, weakness, dizziness, confusion, or an irregular heartbeat contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobamist Respules 5X5 ml:
Takin human immunoglobulin with Tobamist Respules 5X5 ml may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Tobamist Respules 5X5 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Tobamist Respules 5X5 ml to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Tobamist Respules 5X5 ml.
  • Avoid intake of alcoholic beverages with Tobamist Respules 5X5 ml as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Tobamist Respules 5X5 ml in fighting off infections.

Side Effects of Tobamist Respules 5X5 ml

  • Runny or stuffy nose, sneezing
  • Voice alteration (hoarseness)
  • Discolouration of the substance you cough up (sputum)
  • Worsening of lung function test results
  • Generally feeling unwell
  • Muscle pain
  • Voice alteration with a sore throat
  • Difficulty swallowing (laryngitis)

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.

Please do not stop using Tobamist Respules 5X5 ml until the course prescribed by your doctor has been completed. If you stop taking Tobamist Respules 5X5 ml too soon, your symptoms may recur.

Voice alteration (hoarseness) is the most common side effect of Tobamist Respules 5X5 ml. If you experience any major changes, immediately consult your doctor.

Tobamist Respules 5X5 ml is recommended not to use it for more than the prescribed duration. Please reach out to your doctor if your symptoms do not improve or if it becomes worse.

Tobamist Respules 5X5 ml is only used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients.

Drug-Drug Interactions Checker List

  • SALBUTAMOL
  • FUROSEMIDE
  • ETHACRYNIC ACID
  • MANNITOL

Disease/Condition Glossary

Pseudomonas aeruginosa infection: Pseudomonas aeruginosa is a type of bacteria that can cause lung or chest infections, especially in people who already have a lung disease (cystic fibrosis) or an issue with their immune system.

Cystic fibrosis: Cystic fibrosis is a hereditary disease that affects the digestive system and lungs. In this condition, the body produces a thick, sticky fluid that obstructs the pancreas and clogs the lungs.

Have a query?

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Alcohol

Safe if prescribed

It is unknown if alcohol affects Tobamist Respules 5X5 ml. However, it is advisable to limit or avoid alcohol as a precautionary measure.

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Pregnancy

Consult your doctor

Tobamist Respules 5X5 ml may not be recommended to be used in pregnancy. If you are pregnant, please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor as there is no substantial research yet on using Tobamist Respules 5X5 ml in breastfeeding/nursing mothers.

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Driving

Safe if prescribed

Tobamist Respules 5X5 ml may not affect your ability to drive, use, or operate machines.

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Liver

Consult your doctor

Limited information about the usage of Tobamist Respules 5X5 ml in patients with liver disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobamist Respules 5X5 ml.

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Kidney

Consult your doctor

Limited information about the usage of Tobamist Respules 5X5 ml in patients with kidney disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobamist Respules 5X5 ml.

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Children

Safe if prescribed

Children and adolescents aged six and up are eligible to use Tobamist Respules 5X5 ml. Tobamist Respules 5X5 ml should not be given to children under the age of six.

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