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  3. Tobihale 300Mg/5Ml Respules 7'S

Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Composition :

TOBRAMYCIN-300MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Tobihale Respules

Tobihale Respules is an aminoglycoside antibiotic used to treat bacterial infections. It is mostly used to treat eye infections such as conjunctivitis. Besides this, it is also useful in the treatment of various bacterial infections of the brain and spinal cord (meningitis), stomach or intestinesbladder or kidney (urinary tract infection), lungs (pneumonia), and also used for infections of the bone, skin or soft tissue including burns. A bacterial infection is a condition in which bacteria grows in the body and cause infection. It can target any body part and multiply very quickly. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick.

Tobihale Respules contains tobramycin. It inhibits bacteria growth by interfering with protein synthesis. It binds to the proteins in the bacteria, disrupting the cell membrane, and eventually leading to cell death. It is active against various gram-negative bacteria and gram-positive bacteria (Staphylococcus aureus). It will not work for other types of infections such as viral, fungal, or parasitic infections.

It is available in the form of drops, ointment, injection, and inhalation. Tobihale Respules can cause some common side-effects (when eye drops are used) including redness, itching, swelling, burning sensation, tearing, and temporary blurred vision (with ointment use). Long term use of eye drops may cause a fungal eye infection. So, take this medicine for a duration prescribed by your doctor. When given as an injection, you may experience fever, rash, pain at the injection site, confusion, headache, and diarrhoea. Some patients may also experience serious side-effects such as hearing problems, muscle twitching, and convulsions that may require medical attention.

Inform your doctor if you are allergic to Tobihale Respules , other aminoglycoside antibiotics, or any other ingredients present in it. Inform your doctor if you are using other antibiotics, antifungal medication, antiviral drugs, diuretics, general anaesthetics, anti-cancer medicine, immune suppressant, and medications used to treat muscle weakness. Tell your doctor if you have myasthenia gravis (muscle disorders), Parkinson’s disease (a brain disorder), and kidney problems. Inform your doctor if you have any vision problems after using this medication. Tell your doctor if you are pregnant or breastfeeding.

Uses of Tobihale Respules

Bacterial infections

Directions for Use

Eye drops: Wash your hands thoroughly with water before and after use. Tilt your head back and pull down the lower eyelid to create a small sac. Take the prescribed amount of dose with the dropper and squeeze out a drop. Close your eyes for about 2 to 3 minutes. Wipe any excess liquid with a tissue. Do not wipe or rinse the dropper tip after use. Place the dropper back on the bottle and tighten the cap. Ointment: Eye ointment is also used similarly. Create a pocket pulling the lower eyelid while tilting your head back. Then, squeeze out a prescribed amount of ointment and close your eyes. You may experience blurred vision for some time after opening the eyes. So, rest for a while before doing anything. Injections: Injections are given using a syringe. Do not self-administer. Injections are given only by a healthcare professional. The prescribed dose is taken and injected into a muscle or vein. Infusions are given in the form of a drip into the vein by a healthcare professional. Inhalation: Inhalations are used by inhaling the medicine with the use of a nebulizer or inhaler. Do not mix or dilute the medicine unless advised by your doctor. Do not swallow it by mouth. Note: In case of drops/ointment, do not touch the tip of the dropper or ointment tube as it may contaminate the contents. Do not place the tip directly into the eye while instilling drops or ointment. If the dropper touches the eye, immediately squeeze two to three drops onto the tissue and wipe the dropper’s tip with saltwater.

Medicinal Benefits

Tobihale Respules  belongs to a class of drugs called aminoglycoside antibiotics. It works by stopping the growth of bacteria. It reduces the infection by inhibiting bacterial growth. It irreversibly binds to a site on the bacterial ribosomes (ribosomes are responsible for protein synthesis), inhibiting protein formation. Proteins are essential for bacterial growth. So, if bacteria cannot make proteins, it will eventually die.

Side effects of Tobihale 300Mg/5Ml Respules
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
  • Drink plenty of water to promote filtration and elimination.
  • Eat protein-rich foods like seeds, nuts, beans, and lean meats.
  • Include fruits, vegetables and whole foods into your diet.
  • Limit salt, sugar, and saturated fats.
  • Choose healthy fats and oils like olive oil and flaxseed oil.
  • Exercise regularly to promote circulation and lymph vessel activity.
  • Practice compression therapy and wear compression garments.
  • Massage therapy can help move fluid through the lymphatic system.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Drug Warnings

Inform your doctor if you are allergic to Tobihale Respules , other aminoglycoside antibiotics, or any other ingredients present in it. Inform your doctor if you are using any prescription, nonprescription medications, nutritional supplements, or herbal products. Inform your doctor if you are using other antibiotics, antifungal medication, diuretics, general anaesthetics, chemotherapeutic agents, immune suppressants, and medications used to treat muscle weakness. Inform your doctor if you have any history of myasthenia gravis, Parkinson’s diseases, kidney problems, and eye problems. Inform your doctor if you have any vision problems after using this medication. Do not drive or operate heavy machinery until your vision stabilizes. Tell your doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

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TobramycinMannitol
Severe

Drug-Drug Interactions

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How does the drug interact with Tobihale 300Mg/5Ml Respules:
Coadministration of cidofovir with Tobihale 300Mg/5Ml Respules can cause kidney problems.

How to manage the interaction:
Taking Tobihale 300Mg/5Ml Respules with Cidofovir is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
TobramycinMannitol
Severe
How does the drug interact with Tobihale 300Mg/5Ml Respules:
Taking mannitol with Tobihale 300Mg/5Ml Respules can increase the risk of hearing loss and kidney problems.

How to manage the interaction:
Although taking Tobihale 300Mg/5Ml Respules and Mannitol together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without talking to your doctor.
TobramycinDoxacurium chloride
Severe
How does the drug interact with Tobihale 300Mg/5Ml Respules:
Taking Tobihale 300Mg/5Ml Respules with doxacurium chloride can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Although there is a possible interaction between Tobihale 300Mg/5Ml Respules and Doxacurium chloride, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobihale 300Mg/5Ml Respules:
Takin human immunoglobulin with Tobihale 300Mg/5Ml Respules may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Tobihale 300Mg/5Ml Respules together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
TobramycinFoscarnet
Severe
How does the drug interact with Tobihale 300Mg/5Ml Respules:
Combining Tobihale 300Mg/5Ml Respules with Foscarnet can increase the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Tobihale 300Mg/5Ml Respules and foscarnet, but it can be taken if prescribed by a doctor. However, if you experience nausea, swelling, sudden weight gain or weight loss, severe pain in your upper stomach spreading to your back, seizures, pounding heart beats, dizziness or chest pain contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
TobramycinBumetanide
Severe
How does the drug interact with Tobihale 300Mg/5Ml Respules:
When Tobihale 300Mg/5Ml Respules is taken with Bumetanide, the amount of Tobihale 300Mg/5Ml Respules in the blood can go up.

How to manage the interaction:
Although there is a possible interaction between Tobihale 300Mg/5Ml Respules and Bumetanide, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
TobramycinCisatracurium
Severe
How does the drug interact with Tobihale 300Mg/5Ml Respules:
Combining Tobihale 300Mg/5Ml Respules together with cisatracurium can increase the neuromuscular blocking effects( disorder that effects nerves and muscles) of cisatracurium.

How to manage the interaction:
Although there is a possible interaction between Cisatracurium and Tobihale 300Mg/5Ml Respules, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - having trouble breathing contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobihale 300Mg/5Ml Respules:
Coadministration of Tobihale 300Mg/5Ml Respules with Sirolimus can cause an increased risk or severity of kidney problems.

How to manage the interaction:
Although taking Sirolimus and Tobihale 300Mg/5Ml Respules together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Tobihale 300Mg/5Ml Respules:
Using Vecuronium with Tobihale 300Mg/5Ml Respules can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Co-administration of Tobihale 300Mg/5Ml Respules with Vecuronium can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tobihale 300Mg/5Ml Respules:
Using Atracurium with Tobihale 300Mg/5Ml Respules can increase the risk of respiratory depression (breathing disorder).

How to manage the interaction:
Although there is a interaction between Tobihale 300Mg/5Ml Respules and Atracurium, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Sleep for at least six to eight hours to rejuvenate your eyes in a natural way.
  • Wash your eyes with clean water at least two to three times a day
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Keep your ear clean and dry.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • VANCOMYCIN
  • KANAMYCIN
  • GENTAMICIN
  • STREPTOMYCIN
  • FUROSEMIDE
  • NEOSTIGMINE
  • PYRIDOSTIGMINE
  • CYCLOSPORINE
  • AMPHOTERICIN B
  • CISPLATIN
  • CEPHALOTHIN
  • ETHACRYNIC ACID

Special Advise

Tobihale Respules may alter liver and kidney function, and blood cells count. So, laboratory tests may be performed to monitor these levels. Your doctor may also check for vision and hearing problems. 

Disease/Condition Glossary

Conjunctivitis: Conjunctivitis is an eye condition caused by infection or allergies.

Meningitis: Meningitis is an infection of the protective membranes that surround the brain and spinal cord (meninges).

Pneumonia: Pneumonia is swelling (inflammation) of the tissue in one or both lungs. It's usually caused by a bacterial infection. It can also be caused by a virus, such as a coronavirus (COVID-19).

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