apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
Insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Tolvacare Tablet 4's

Tolvacare Tablet 4's, Pack of 4
Tolvacare Tablet 4's, Pack of 4
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
Know More
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

TOLVAPTAN-15MG

Manufacturer/Marketer :

Rennovs Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

About Tolvacare Tablet 4's

Tolvacare Tablet 4's belongs to a group of medicines called vasopressin V2 receptor antagonist used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Additionally, Tolvacare Tablet 4's is also used to treat autosomal dominant polycystic kidney disease (ADPKD).
 
Tolvacare Tablet 4's contains ‘tolvaptan’ that works by blocking the effect of vasopressin, resulting in decreased water reabsorption, a net increase in free water excretion (aquaresis) and an increase in serum sodium concentrations. This decrease in free water is not associated with an increased excretion of sodium or potassium ions, the increase in serum sodium concentration is solely a result of  increased urine production
 
You are advised to take Tolvacare Tablet 4's for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, headache, dry mouth, fatigue, diarrhoea, thirst and increased urge to urinate. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Do not take Tolvacare Tablet 4's if you are pregnant as it may cause foetal harm. Consult your doctor before taking Tolvacare Tablet 4's if you are breastfeeding. Tolvacare Tablet 4's is not recommended for children below 18 years as the efficacy and safety have not been established. Tolvacare Tablet 4's may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side-effects.

Uses of Tolvacare Tablet 4's

Hyponatremia (low sodium levels) and autosomal dominant polycystic kidney disease (ADPKD).

Directions for Use

Swallow Tolvacare Tablet 4's as a whole with a glass of water, do not crush, break or chew it.

Medicinal Benefits

Tolvacare Tablet 4's belongs to a group of medicines called vasopressin V2 receptor antagonist. Tolvacare Tablet 4's is used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Besides this, Tolvacare Tablet 4's is also used to treat autosomal dominant polycystic kidney disease (ADPKD). Tolvacare Tablet 4's works by blocking the effect of vasopressin, a hormone which is involved in the formation of cysts in ADPKD patients. By blocking the effect of vasopressin, Tolvacare Tablet 4's slows down the development of cysts in kidneys and reduces the symptoms of the disease. Tolvacare Tablet 4's antagonises the effect of vasopressin, this results in an increase in free water clearance and decreases urine osmolality due to increased urinary excretion, thereby increases serum sodium concentrations.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tolvacare Tablet
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink six to eight glasses of water per day to be healthy.
  • Healthy urinary habits can help minimize pollakiuria (frequent urinating).
  • Avoid liquids containing caffeine, artificial sweeteners, and soda, as they might cause bladder discomfort.
  • Add bladder-friendly foods such as omega-3 fatty acids, blueberries, and cranberries.
  • Reduce fluid intake 2-3 hours prior to bedtime.
  • Limit alcohol and caffeine as they can increase urination and affect bladder health.
  • Maintain sleep hygiene.
  • Eat a low-salt and healthy diet.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.

Drug Warnings

Do not take Tolvacare Tablet 4's if you are allergic to any of its contents, if you have raised liver enzymes in the blood, very low blood volume, if there is no urine production, if you cannot tell that you are thirsty. Inform your doctor if you have liver disease, difficulty in urination, diabetes, high levels of uric acid, advanced kidney disease or if you have to restrict fluid intake due to certain medical conditions. Do not take Tolvacare Tablet 4's if you are pregnant as it may cause foetal harm. Consult your doctor before taking Tolvacare Tablet 4's if you are breastfeeding. Tolvacare Tablet 4's is not recommended for children below 18 years as efficacy and safety have not been established. Tolvacare Tablet 4's may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. 

Drug-Drug Interactions

verifiedApollotooltip
TolvaptanMifepristone
Critical
TolvaptanIndinavir
Critical

Drug-Drug Interactions

Login/Sign Up

TolvaptanMifepristone
Critical
How does the drug interact with Tolvacare Tablet:
When Tolvacare Tablet is taken with Mifepristone, it may increase the levels of Tolvacare Tablet, which may increase the risk of side effects.

How to manage the interaction:
Taking Tolvacare Tablet and Mifepristone together is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
TolvaptanIndinavir
Critical
How does the drug interact with Tolvacare Tablet:
When Tolvacare Tablet and Indinavir are taken together, may significantly increase the blood levels and effects of Tolvacare Tablet.

How to manage the interaction:
There may be a possibility of interaction between Tolvacare Tablet and Indinavir, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
TolvaptanItraconazole
Critical
How does the drug interact with Tolvacare Tablet:
Co-administration of Tolvacare Tablet and Itraconazole may significantly raise Tolvacare Tablet blood levels and effects.

How to manage the interaction:
There may be a possibility of interaction between Tolvacare Tablet and Itraconazole, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
TolvaptanDelavirdine
Critical
How does the drug interact with Tolvacare Tablet:
When Tolvacare Tablet and Delavirdine are taken together, may significantly increase the blood levels and effects of Tolvacare Tablet.

How to manage the interaction:
There may be a possibility of interaction between Tolvacare Tablet and Delavirdine, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
TolvaptanNefazodone
Critical
How does the drug interact with Tolvacare Tablet:
When Tolvacare Tablet and Nefazodone are taken together, may significantly increase the blood levels and effects of Tolvacare Tablet.

How to manage the interaction:
There may be a possibility of interaction between Tolvacare Tablet and Nefazodone, but it can be taken if prescribed by a doctor. If you notice any of these signs - like difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
TolvaptanRitonavir
Critical
How does the drug interact with Tolvacare Tablet:
Taking Ritonavir and Tolvacare Tablet may significantly increase the blood levels of Tolvacare Tablet.

How to manage the interaction:
Taking Tolvacare Tablet with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, fits, contact a doctor. Do not discontinue any medications without consulting a doctor.
TolvaptanAtazanavir
Critical
How does the drug interact with Tolvacare Tablet:
When Tolvacare Tablet and Atazanavir are taken together, may significantly increase the blood levels and effects of Tolvacare Tablet.

How to manage the interaction:
There may be a possibility of interaction between Tolvacare Tablet and Atazanavir, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
TolvaptanPosaconazole
Critical
How does the drug interact with Tolvacare Tablet:
Taking Tolvacare Tablet and Posaconazole together results in an increase in the levels and effects of Tolvacare Tablet.

How to manage the interaction:
Although there is an interaction between Tolvacare Tablet and Posaconazole, it can be taken if prescribed by a doctor. However, consult a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures (fits). Do not stop using any medications without a doctor's advice.
TolvaptanVoriconazole
Critical
How does the drug interact with Tolvacare Tablet:
Co-administration of Tolvacare Tablet together with Voriconazole may significantly increase the blood levels and effects of Tolvacare Tablet.

How to manage the interaction:
There may be a possibility of interaction between Tolvacare Tablet and Voriconazole, but it can be taken if prescribed by a doctor. If you experience difficulty swallowing, trouble speaking, muscle weakness call a doctor right away. Do not stop using any medications without a doctor's advice.
TolvaptanSaquinavir
Critical
How does the drug interact with Tolvacare Tablet:
When Tolvacare Tablet and Saquinavir are taken together, may significantly increase the blood levels and effects of Tolvacare Tablet.

How to manage the interaction:
There may be a possibility of interaction between Tolvacare Tablet and Saquinavir, but it can be taken if prescribed by a doctor. If you notice any of these signs - like difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
TOLVAPTAN-15MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

Login/Sign Up

TOLVAPTAN-15MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit

How to manage the interaction:
Consuming grapefruit juice while taking Tolvacare Tablet can increase the effects of Tolvacare Tablet. Avoid taking Tolvacare Tablet with grapefruit juice.

Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Manage stress with meditation, yoga, and massage.
  • Drink plenty of fluids.
  • Rehydration beverages that contain electrolytes are also helpful.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Tolvacare Tablet 4's Substitute

Substitutes safety advice

  • Natrise Tablet 4's

    by Others

    ₹132.07per tablet

  • Hyponat-O 15 Tablet 10's

    by Others

    ₹67.28per tablet

  • Tolvat 15 Tablet 4's

    by Others

    ₹138.60per tablet

  • Vaptan Tablet 10's

    by AYUR

    ₹90.00per tablet

  • Resodim 15 Tablet 4's

    by Others

    ₹180.68per tablet

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Aug 20, 2024 | 12:54 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

FAQs

Tolvacare Tablet 4's works by blocking the effect of vasopressin, a hormone which is involved in the formation of cysts in ADPKD patients. By blocking the effect of vasopressin, Tolvacare Tablet 4's slows down the development of cysts in kidneys, reduces the symptoms of the disease, and increases urine production. Thereby increases serum sodium concentrations.

Dry mouth could be a side-effect of Tolvacare Tablet 4's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Diarrhoea could be a side-effect of Tolvacare Tablet 4's. Drink plenty of fluid to prevent dehydration if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in stools.

Tolvacare Tablet 4's may cause the liver to not work properly. Consult your doctor immediately if you experience nausea, vomiting, fever, loss of appetite, abdominal pain, tiredness, dark urine, jaundice, itching and flu-like symptoms.

Tolvacare Tablet 4's may cause water loss due to increased urine production. This might result in side-effects such as thirst, dry mouth and kidney problems. To prevent this, drink plenty of water regularly. Drink 1-2 glasses of water before going to bed even though you are not thirsty. Special care must be taken in patients with diseases that might reduce fluid intake.

Consult your doctor before taking Tolvacare Tablet 4's if you are diabetic as Tolvacare Tablet 4's might increase the blood sugar levels. Regular monitoring of blood glucose levels while taking Tolvacare Tablet 4's is advised.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • TELITHROMYCIN
  • SULPHAMETHOXAZOLE+TRIMETHOPRIM
  • KETOCONAZOLE
  • ITRACONAZOLE
  • RITONAVIR
  • INDINAVIR
  • SAQUINAVIR
  • NELFINAVIR
  • NEFAZODONE
  • SPIRONOLACTONE
  • VALSARTAN
  • SACUBITRIL
  • HEPARIN

Special Advise

  • Regular monitoring of liver functioning and electrolyte levels while taking Tolvacare Tablet 4's is advised.
  • Treatment with Tolvacare Tablet 4's should be started and re-started in a hospital or in the presence of a healthcare professional to monitor the sodium levels in your blood closely.

Disease/Condition Glossary

Hyponatremia: Sodium is an important electrolyte that helps in maintaining water balance in and around the cells. It helps in proper nerve, muscle functioning and maintains stable blood pressure levels. Low levels of sodium in the blood are referred to as hyponatremia. Normal levels of sodium are 135-145 milliequivalance per litre. Hyponatremia occurs when the level is below 135mEq/L. Symptoms include weakness, tiredness, nausea, vomiting, headache, irritability, confusion and muscle spasms.

Autosomal Dominant Polycystic Kidney Disease (ADPKD): It is an inherited disorder in which cysts are developed in the kidney. These cysts are non-cancerous sacs that contain a water-like fluid which puts pressure on the surrounding tissues, leading to reduced kidney function. Symptoms include high blood pressure, swollen abdomen, and back or side pain.

Have a query?

whatsapp Floating Button