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Written By ,
Reviewed By Sureshvarma D , MPharma
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in last 90 days

Manufacturer/Marketer

Lupin Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Tonact Plus Tablet 10's

Tonact Plus Tablet 10's belongs to a class of medications called antilipemic (cholesterol-lowering agent). Tonact Plus Tablet 10's is used to treat raised cholesterol levels in our body. Tonact Plus Tablet 10's helps lower the level of low-density lipoprotein (LDL) or bad cholesterol in the blood and increases high-density lipoprotein (HDL) or good cholesterol. Dyslipidaemia is the deposition of unhealthy levels of fats (lipid) in the blood. In this condition, there is always a high level of low-density lipoprotein (LDL or bad cholesterol), triglycerides (TG), and a low level of high-density lipoprotein (HDL or good cholesterol). Tonact Plus Tablet 10's is an extended-release formulation that releases slowly for a longer duration of time.

Tonact Plus Tablet 10's contains two medicines, namely atorvastatin and nicotinic acid (vitamin B3). Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). On the other hand, Tonact Plus Tablet 10's contains nicotinic acid, which is a form of vitamin B that further increases good cholesterol levels (HDL).

Take Tonact Plus Tablet 10's as prescribed by your doctor. You are advised to take Tonact Plus Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience constipation, nausea, stomach pain, weakness, muscle pain, headache, dizziness, itching, flushing of the skin, the increased glucose level in the blood. Most of these side effects of Tonact Plus Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Tonact Plus Tablet 10's if you are allergic to Tonact Plus Tablet 10's, or any other ingredients present in it. Tonact Plus Tablet 10's should not be taken in conditions like liver disease or kidney disease. Tonact Plus Tablet 10's should not be prescribed to children less than 10 years of age. Immediately inform your doctor before taking Tonact Plus Tablet 10's if you are pregnant or planning to get pregnant, breastfeeding. Tonact Plus Tablet 10's has negligible influence on the ability to drive and use machines. Do not drink too much while taking this medicine.

Uses of Tonact Plus Tablet 10's

High cholesterol.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Tonact Plus Tablet 10's taken with dietary measures helps treat high cholesterol, especially for heart patients when initial dietary measures fail to lower cholesterol. It helps lower the bad cholesterol (LDL) and increases the level of good cholesterol (HDL) in the state of dyslipidemia or hyperlipidemia. Tonact Plus Tablet 10's is considered more effective compared to other cholesterol-lowering medicines. Tonact Plus Tablet 10's also lowers the amount of fat or cholesterol deposition (plaque) in the heart's arteries, thereby reducing the chance of having a heart attack or stroke in the future. Tonact Plus Tablet 10's contains nicotinic acid, which is a form of vitamin B that further increases good cholesterol levels (HDL). 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tonact Plus Tablet 10's

  • Constipation
  • Nausea
  • Stomach pain
  • Weakness
  • Muscle pain
  • Abnormal heart rhythm
  • Abnormal liver function tests
  • Headache
  • Arthralgia
  • Dizziness
  • Diarrhea
  • Itching
  • Peripheral Edema
  • Flushing of skin
  • Increased glucose level in the blood

Drug Warnings

Tonact Plus Tablet 10's may cause a breakdown of skeletal muscle tissue, leading to kidney failure. This condition usually occurs in the elderly, people with kidney disease, and poorly controlled hypothyroidism (underactive thyroid). Tonact Plus Tablet 10's should not be prescribed to children less than 10 years of age. You should contact a doctor before if you have had an allergic reaction to Tonact Plus Tablet 10's, have a liver problem (jaundice, liver cirrhosis), or kidney problems, pregnant or planning to get pregnant, breastfeeding, have severe lung disease, have a previous heart attack or stroke caused by bleeding in the brain, have hypothyroidism, drink more than 2 servings of alcohol per day and have a muscle disorder (fibromyalgia) and damaged muscle tissue (rhabdomyolysis).

Drug-Drug Interactions

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AtorvastatinPosaconazole
Critical
AtorvastatinMipomersen
Severe

Drug-Drug Interactions

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AtorvastatinPosaconazole
Critical
How does the drug interact with Tonact Plus Tablet:
Taking Tonact Plus Tablet with Posaconazole can increase the blood levels of Tonact Plus Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Tonact Plus Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AtorvastatinMipomersen
Severe
How does the drug interact with Tonact Plus Tablet:
Coadministration of Tonact Plus Tablet with Mipomersen may increase the risk of liver problem.

How to manage the interaction:
Co-administration of Tonact Plus Tablet with Mipomersen can result in an interaction, but it can be taken if a doctor has advised it. Call a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
AtorvastatinRifampicin
Severe
How does the drug interact with Tonact Plus Tablet:
Taking Tonact Plus Tablet with rifampicin can decrease the blood levels of Tonact Plus Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Tonact Plus Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AtorvastatinTeriflunomide
Severe
How does the drug interact with Tonact Plus Tablet:
Coadministration of Tonact Plus Tablet and Teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Taking Tonact Plus Tablet and teriflunomide together can result in an interaction, it can be taken if a doctor has advised it. However, if you happen to experience, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you are advised to seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
AtorvastatinDanazol
Severe
How does the drug interact with Tonact Plus Tablet:
Using Tonact Plus Tablet together with danazol may significantly increase the blood levels of Tonact Plus Tablet.

How to manage the interaction:
Concomitant administration of Tonact Plus Tablet along with danazol can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop taking any medication without doctor's advice.
AtorvastatinLetermovir
Severe
How does the drug interact with Tonact Plus Tablet:
The combination of Tonact Plus Tablet and letermovir may substantially elevate the blood levels of Tonact Plus Tablet. This can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Tonact Plus Tablet with letermovir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinLomitapide
Severe
How does the drug interact with Tonact Plus Tablet:
Coadministration of Tonact Plus Tablet with Lomitapide may increase the blood levels of lomitapide.

How to manage the interaction:
There may be a possibility of interaction between Tonact Plus Tablet and Lomitapide, but it can be taken if prescribed by a doctor. Seek immediate medical attention if you develop signs and symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
AtorvastatinFosamprenavir
Severe
How does the drug interact with Tonact Plus Tablet:
Using Tonact Plus Tablet together with fosamprenavir may significantly increase the blood levels of Tonact Plus Tablet.

How to manage the interaction:
Although there is a possible interaction between Tonact Plus Tablet and Fosamprenavir, you can take these medicines together if prescribed by a doctor. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
AtorvastatinAmprenavir
Severe
How does the drug interact with Tonact Plus Tablet:
Using Tonact Plus Tablet together with amprenavir may significantly increase the blood levels of Tonact Plus Tablet.

How to manage the interaction:
Although taking Tonact Plus Tablet and Amprenavir together can cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on your health and talk to a doctor about any concerns. If you notice any of these signs - muscle pain, dark urine, fever, or fatigue - make sure to contact a doctor right away. They can help figure out what's going on and how to help you feel better. Do not stop using any medications without talking to a doctor.
AtorvastatinBoceprevir
Severe
How does the drug interact with Tonact Plus Tablet:
Using Tonact Plus Tablet together with boceprevir may significantly increase the blood levels of Tonact Plus Tablet.

How to manage the interaction:
Co-administration of Tonact Plus Tablet with Boceprevir can result in an interaction, but it can be taken if a doctor has advised it. You should also seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try aromatherapy, yoga, meditation to help relax your body and mind.
  • Try to do breathing exercises to get more oxygen.
  • Eat a healthy diet rich in soluble fiber like beans, legumes, whole grain, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short span of time. Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, fish, and low in red meat and most dairy.
  • Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants that help to lower LDL
  • Minimize the intake of added sugar. The American Heart Association (ADA) recommends, one should not eat more than 100 calories (25 grams) of added sugar for women and children and no more than 150 calories (37.5 grams) for men every day.
  • American Heart Association recommends sodium chloride intake (table salt) should not exceed more than 2,300 mg per day as part of a healthy eating pattern.
  • As a precautionary measure, do not consume alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • GEMFIBROZIL
  • ITRACONAZOLE
  • RITONAVIR
  • DIGOXIN
  • WARFARIN
  • VERAPAMIL
  • DILTIAZEM

Special Advise

If muscle fatigue or muscle pain affects your daily activity. Try to contact a doctor if you have muscle weakness or fatigue.

Disease/Condition Glossary

High cholesterol: Cholesterol is a waxy substance produced by the liver to protect nerves, make tissue, and various hormones. Our body also receives cholesterol from the food we eat, like cooking oils, eggs, meats, and dairy products. Excess cholesterol is bad for our health. There are two types of cholesterol, namely 'bad cholesterol' and 'good cholesterol'. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG), while good cholesterol consists of high-density lipoprotein (HDL). Usually, there are no specific symptoms of raised or high cholesterol levels but a large deposition of cholesterol in the arteries (plaque) or heart blockage. Blocked artery or plaque formation in the heart's arteries can lead to chest pain (angina), heart attack, or stroke. It is advisable to have complete cholesterol tests (lipid profile test) at least once a year. It will help you to closely monitor your heart health and risk of heart attack and stroke. 

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