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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

TOPIRAMATE-25MG

Manufacturer/Marketer :

Knoll Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Topiranol-25Mg Tablet

Topiranol-25Mg Tablet belongs to a group of medicines called “antiepileptic (AED)/ anticonvulsant agent' that is primarily indicated in the treatment of epilepsy (Monotherapy and Adjunctive therapy) and It can also be taken to prevent migraine. Epilepsy is a chronic disorder that is responsible for causing unprovoked, recurrent seizures in the body. A seizure is a sudden attack in the brain that makes a person lose control of their actions. Migraine is a mental condition that often causes intense or debilitating headaches with difficulty speaking, nausea, vomiting, and sensitivity to light or sound.

Topiranol-25Mg Tablet is responsible for restoring the balance of neural activity by diminishing the spread of seizure movement in the brain. By controlling the electrical activity of the brain, it controls seizures and relieves the symptoms of migraine. Take Topiranol-25Mg Tablet in an empty stomach without food with one glass of water. Topiranol-25Mg Tablet is only available on prescription. It comes as tablets or capsules intended to be taken by mouth only. Swallow the medication as a whole without crushing or breaking it. Topiranol-25Mg Tablet doses are sometimes advised according to the weight of children so the doctor will change the dose if the child gains or lose weight.

The possible side effects of topiramate include feeling sleepy, dizziness, diarrhoea and feeling sick. Some of the side effects do not even require medical attention and these are usually mild and go away by themselves. Consult with the doctor if any of these side effects continue or get worse with time.

The use of $mame is restricted in persons who are hypersensitive to it, so tell your doctor if you have any allergy to any of the chemical constituents present in this medicine. Tell your doctor if you ever had or already dealing with diarrhoea, glaucoma, metabolic acidosis, lung disease, breathing problems, liver disease, a blood disorder called acute porphyria etc. If a woman is pregnant or planning to pregnant then they should tell their doctor as the use of this medicine during pregnancy may increase the risk of cleft lip and/or cleft palate which is a birth defect in the newborn that may develop during early pregnancy.

Uses of Topiranol-25Mg Tablet

Epilepsy, Migraine

Directions for Use

Tablet: It can be taken irrespective of meals. Swallow the tablet as a whole with a glass of water. Do not chew the tablet. Sprinkle capsule: You may swallow the capsule as a whole or you may open the capsule and sprinkle the entire contents on a teaspoon of soft food. Drink fluids immediately after eating this medicine and food mixture to make sure it is swallowed. Do not store this mixture for later use.

Medicinal Benefits

Topiranol-25Mg Tablet is an antiepileptic (AED) medicine that is used to treat epilepsy in mono or adjunctive therapy and migraine. In Monotherapy epilepsy, Topiranol-25Mg Tablet is suggested for patients above 2 years of age with partial-onset or primary generalized tonic-clonic seizures. In Adjunctive therapy epilepsy, Topiranol-25Mg Tablet is suggested in patients of 2 to 16 years of age with partial-onset seizures or primary generalized tonic-clonic seizures while in patients more than 2 years of age, Topiranol-25Mg Tablet is suggested in patients with seizures associated with Lennox-Gastaut syndrome (LGS). In migraine, Topiranol-25Mg Tablet is suggested for prophylaxis of migraine. Topiranol-25Mg Tablet works by blocking the voltage-dependent sodium and calcium channels and increasing the inhibitory actions of GABA. In epilepsy, Topiranol-25Mg Tablet controls the uncontrolled activity of nerves in the brain and thus prevents or controls seizures. While in migraine, Topiranol-25Mg Tablet tranquilizes the overactive nerve cells in the brain that are responsible for causing migraine.

Storage

Store in a cool and dry place away from sunlight
Side effects of Topiranol-25Mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

Topiranol-25Mg Tablet may cause a congenital disability called cleft lip in unborn baby, so the use of this medicine is not allowed in pregnant females. Topiranol-25Mg Tablet may increase the body temperature and reduce sweating, so one should report it to the doctor if they are noticing decreased sweating and hot, dry skin. Topiranol-25Mg Tablet may enhance the level of acid in the blood so one should tell their doctor if they have irregular heartbeats or loss of hunger. Before taking Topiranol-25Mg Tablet , tell the doctor if you have diarrhoea, metabolic acidosis, eye problems, liver disease. Topiranol-25Mg Tablet may affect the working of contraceptives that include the combined pill, vaginal ring, patches,progestogen-only contraceptive pill, and emergency contraception. So, one should tell their doctor if they are using any contraceptives to prevent pregnancy.

Drug-Drug Interactions

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TopiramateOrphenadrine (citrate)
Severe

Drug-Drug Interactions

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TopiramateOrphenadrine (citrate)
Severe
How does the drug interact with Topiranol-25Mg Tablet:
Combining Orphenadrine with Topiranol-25Mg Tablet can increase the risk of overheating and reduced sweating.

How to manage the interaction:
Although there is a possible interaction between Orphenadrine (citrate) and Topiranol-25Mg Tablet, you can take these medicines together if prescribed by your doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Topiranol-25Mg Tablet:
Topiranol-25Mg Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like clomipramine.

How to manage the interaction:
Although taking Topiranol-25Mg Tablet and Clomipramine together can cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Topiranol-25Mg Tablet:
When Pimozide is taken with Topiranol-25Mg Tablet, it can cause the body to process Pimozide faster.

How to manage the interaction:
Although taking Pimozide and Topiranol-25Mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Topiranol-25Mg Tablet:
Coadministration of Amitriptyline and Topiranol-25Mg Tablet may cause increased body temperature and decreased sweating.

How to manage the interaction:
Amitriptyline and sodium oxybate interact, however if a doctor prescribes them, they can still be taken. Consult a doctor if you have symptoms like sleepiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or rapid breathing, or impairment in thinking. Never stop taking any medication without consulting a doctor.
How does the drug interact with Topiranol-25Mg Tablet:
Topiranol-25Mg Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like clozapine.

How to manage the interaction:
Taking Topiranol-25Mg Tablet with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. Your doctor can recommend other options that won't cause problems when taken together. It's important to be careful and keep a close eye on your health. Do not stop using any medications without talking to your doctor.
How does the drug interact with Topiranol-25Mg Tablet:
Taking Ziprasidone with Topiranol-25Mg Tablet can increase body temperature and reduced sweating.

How to manage the interaction:
Co-administration of Topiranol-25Mg Tablet with Ziprasidone can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience drowsiness, dizziness, or lightheadedness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Topiranol-25Mg Tablet:
Co-administration of Flavoxate and Topiranol-25Mg Tablet may increase body temperature and decrease sweating. Heat stroke and hospitalization may occur in some people, especially in warm weather and during vigorous exercise.

How to manage the interaction:
Taking Flavoxate and Topiranol-25Mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like drowsiness, dizziness, or lightheadedness, it's a good idea to reach out to your doctor right away. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Topiranol-25Mg Tablet:
Using Tolterodine with Topiranol-25Mg Tablet can increase body temperature and decreased sweating.

How to manage the interaction:
Although there is an interaction between Tolterodine and Topiranol-25Mg Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sleepiness, dizziness, or lightheadedness. Do not discontinue any medications without consulting a doctor.
TopiramatePromazine
Severe
How does the drug interact with Topiranol-25Mg Tablet:
Combining Promazine with Topiranol-25Mg Tablet can increase the risk of overheating and reduced sweating.

How to manage the interaction:
Although there is a possible interaction between Topiranol-25Mg Tablet and Promazine, you can take these medicines together if prescribed by your doctor. Your doctor can recommend other options that won't cause problems when taken together. It's important to be careful and keep a close eye on things. Do not stop using any medications without a doctor's advice.
How does the drug interact with Topiranol-25Mg Tablet:
Taking Topiranol-25Mg Tablet with meclizine can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although there is a interaction between Meclizine and Topiranol-25Mg Tablet, but it can be taken together if prescribed by your doctor. However, if you experience drowsiness, dizziness, or lightheadedness, increased body temperature and decreased sweating contact your doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a balanced diet that consists of good fats, proteins, carbohydrates, vegetables, and fruit which helps the body and brain to work properly and keep a person healthy and energetic.
  • Fatigue is one of the primary reasons that trigger seizures in the body, so sleeping properly can help in relaxing the brain.
  • One should avoid the consumption of alcohol as it can trigger seizures in patients. Even one or two glasses can trigger epilepsy and worsen the side effects of Topiranol-25Mg Tablet .
  • Keep yourself happy and avoid taking emotional stress as stress causes seizures. Persons who maintain healthy stress levels have reported that they have responded well to the medicine.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Seizures can happen when the brain cells are not working properly or working faster than normal. Topiranol-25Mg Tablet slows down these electrical signals to stop seizures.

No, you should take rest after taking this medicine as this medicine affects the thinking ability and vision of a person so avoid doing any task that requires mental alertness.

Topiranol-25Mg Tablet acts by decreasing the spread of seizure activity in the brain. It also restores the normal balance of neurons which in turn calms the brain. In epilepsy, cells present in the brain talk to each other by generating electric signals. When these cells fail to work properly or working faster than normal then it causes seizures. Topiranol-25Mg Tablet slows down these electrical signals and thus prevents or controls seizures. While in migraine, Topiranol-25Mg Tablet tranquilizes the overactive nerve cells in the brain that are responsible for causing migraine.

Yes, the use of Topiranol-25Mg Tablet is safe for long time use if suggested by the doctor.

Yes, Topiranol-25Mg Tablet may affect the working of contraceptives that include the combined pill, vaginal ring, patches,progestogen-only contraceptive pill, and emergency contraception. Tell your doctor if you are using any type of contraceptives as the doctor may suggest using different types of contraceptives or combined hormonal contraceptives.

No, Topiranol-25Mg Tablet does not affect fertility.

Generally, one should avoid consuming alcohol while taking Topiranol-25Mg Tablet as it may make a person feel sleepy or tired and can cause seizures in some people with epilepsy.

Drug-Drug Interactions Checker List

  • METFORMIN
  • GLIBENCLAMIDE
  • PIOGLITAZONE
  • VENLAFAXINE
  • AMITRIPTYLINE
  • DILTIAZEM
  • HYDROCHLOROTHIAZIDE
  • PROPRANOLOL
  • RISPERIDONE

Disease/Condition Glossary

Epilepsy: It is a neurological disorder in which brain activity becomes abnormal characterized by intense electrical bursts in the brain (seizures). When these bursts happen in one part of the brain it is called a partial seizure while if these bursts occur in the complete brain it is called a generalized seizure. Sometimes, a person starts experiencing the symptoms before starting of seizure that includes a sudden feeling of fear, dizziness, changes in vision, shakiness in arms and legs, and headache. While the symptoms that occur during a seizure include losing consciousness, characterized by confusion, uncontrollable muscle spasms, falling, biting tongue, sudden, rapid eye movements, unusual noises, such as grunting, sudden mood changes, etc.

Migraine: It is a mild to severe headache that starts as a dull ache in the region around the eye. It usually lasts a few hours up to several days and gets worst with the movement. The possible warning signs that can start before the occurrence of migraine include visual changes, unusual tiredness, tingling in an arm or leg. A person facing migraine may also face mild to severe pain in the head, pulsing, throbbing pain in the head, sensitivity to sound and light, vomiting, and Nausea.

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