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  3. Trenaxa MF Tablet 6's

Trenaxa MF Tablet 6's, Pack of 6
Trenaxa MF Tablet 6's, Pack of 6
Trenaxa MF Tablet 6's, Pack of 6
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

MEFENAMIC ACID-250MG + TRANEXAMIC ACID-500MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Trenaxa MF Tablet

Trenaxa MF Tablet is a combination medicine used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, Trenaxa MF Tablet is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Menstrual cramps, also known as dysmenorrhea, are characterized by cramps and pain during menstruation. Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods.

Trenaxa MF Tablet is a combination of two drugs: Tranexamic acid (anti-fibrinolytic) and Mefenamic acid (NSAID). Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.

You are advised to take Trenaxa MF Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, indigestion, heartburn, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Trenaxa MF Tablet may cause dizziness, so drive with caution. Trenaxa MF Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Trenaxa MF Tablet as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Trenaxa MF Tablet

Dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding).

Directions for Use

Take Trenaxa MF Tablet with food to prevent stomach upset. Swallow Trenaxa MF Tablet as a whole with a glass of water, do not chew, or break it.

Medicinal Benefits

Trenaxa MF Tablet is a combination of two drugs, namely: Tranexamic acid and Mefenamic acid. Trenaxa MF Tablet is used to treat abdominal pain, dysmenorrhea (period pain), and menorrhagia (heavy menstrual bleeding). Additionally, Trenaxa MF Tablet is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Tranexamic acid is an anti-fibrinolytic agent that helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid is an NSAID that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Trenaxa MF Tablet helps treat heavy bleeding and pains/cramps during periods.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Trenaxa MF Tablet if you are allergic to any of its contents or if you have severe heart failure. Inform your doctor if you have/had deep vein thrombosis, pulmonary embolism (block a blood vessel in the lungs), coagulopathy (formation of blood clots), epilepsy, irregular periods, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Trenaxa MF Tablet may cause dizziness and drowsiness, so drive only if you are alert. Trenaxa MF Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Trenaxa MF Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Do not take any other NSAIDs for pain relief along with Trenaxa MF Tablet unless prescribed.

Drug-Drug Interactions

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Tranexamic acidMedroxyprogesterone
Critical
Tranexamic acidEthinylestradiol
Critical

Drug-Drug Interactions

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Tranexamic acidMedroxyprogesterone
Critical
How does the drug interact with Trenaxa MF Tablet:
Taking Medroxyprogesterone acetate with Trenaxa MF Tablet may increase the risk of blood clots.

How to manage the interaction:
Taking Medroxyprogesterone with Trenaxa MF Tablet is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
Tranexamic acidEthinylestradiol
Critical
How does the drug interact with Trenaxa MF Tablet:
Taking Ethinylestradiol with Trenaxa MF Tablet may increase the risk of blood clot formation.

How to manage the interaction:
Taking Ethinylestradiol with Trenaxa MF Tablet is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidEtonogestrel
Critical
How does the drug interact with Trenaxa MF Tablet:
Co-administration of Trenaxa MF Tablet may cause blood clotting when taken with Etonogestrel.

How to manage the interaction:
Taking Trenaxa MF Tablet with Etonogestrel is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Tranexamic acidLevonorgestrel
Critical
How does the drug interact with Trenaxa MF Tablet:
Taking Levonorgestrel with Trenaxa MF Tablet may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.

How to manage the interaction:
Taking Trenaxa MF Tablet with Levonorgestrel may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidDrospirenone
Critical
How does the drug interact with Trenaxa MF Tablet:
Taking drospirenone with Trenaxa MF Tablet may increase the risk of blood clot formation.

How to manage the interaction:
Taking Trenaxa MF Tablet with Drospirenone is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Mefenamic acidMeloxicam
Critical
How does the drug interact with Trenaxa MF Tablet:
Co-administration of Trenaxa MF Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Trenaxa MF Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Trenaxa MF Tablet:
Coadministration of Trenaxa MF Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Trenaxa MF Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidEstradiol
Severe
How does the drug interact with Trenaxa MF Tablet:
Co-administration of Estradiol with Trenaxa MF Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking Estradiol with Trenaxa MF Tablet can lead to an interaction; however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidDiethylstilbestrol
Severe
How does the drug interact with Trenaxa MF Tablet:
Co-administration of Diethylstilbestrol with Trenaxa MF Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking Diethylstilbestrol with Trenaxa MF Tablet can possibly lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidConjugated Estrogens
Severe
How does the drug interact with Trenaxa MF Tablet:
Co-administration of Conjugated estrogen with Trenaxa MF Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking Conjugated estrogen with Trenaxa MF Tablet may result in interaction, it can be taken only if your doctor has advised it. However, if you experience chest pain, shortness of breath, coughing up blood, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a healthy diet. Include vegetables, fruits, and whole grains in your meals.
  • Stay hydrated; drink plenty of water.
  • Cut down on sugars, salts, spicy food, coffee, and alcohol.
  • A heating pad can help ease the pain by placing it on the belly or lower back.
  • Exercise can help ease the pain of menstrual cramps.
  • Avoid stress by performing meditation or yoga.
  • Massage your lower back or abdomen to relieve the pain.
  • Take proper rest.

Habit Forming

No

Therapeutic Class

ANTIFIBRINOLYTIC AGENTS

Trenaxa MF Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:34 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Trenaxa MF Tablet contains Tranexamic acid and Mefenamic acid. Tranexamic acid helps the body's natural blood clot process by preventing the breakdown of fibrin, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.

Diarrhoea might be a side-effect of Trenaxa MF Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.

Trenaxa MF Tablet should not be taken for longer durations unless prescribed by the doctor. Trenaxa MF Tablet is usually prescribed for a few days at the time of heavy bleeding and cramps.

Trenaxa MF Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Trenaxa MF Tablet only as prescribed and do not overdose.

Consult your doctor before taking contraceptive pills along with Trenaxa MF Tablet. When taken together, there is an increased risk of deep vein thrombosis (blood clot in the deep vein, usually legs).

Trenaxa MF Tablet contains mefenamic acid, an NSAID which might increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke. Therefore, avoid taking Trenaxa MF Tablet if you have heart-related problems unless prescribed by the doctor.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • CELECOXIB
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE

Disease/Condition Glossary

Menorrhagia: Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods. The exact cause of menorrhagia is unknown, but it could be due to hormonal imbalance, dysfunction of the ovaries, uterine fibroids, polyps, inherited bleeding disorders, intrauterine devices, or medications. Symptoms include socking through one/more sanitary pads/tampons for every hour, needing to use double sanitary protection to control the flow, needing to wake up during the night to change the pad, bleeding for more than a week, passing blood clots, unable to do daily activities due to heavy flow, tiredness, and fatigue.

Dysmenorrhea: Menstrual cramps, also known as dysmenorrhea, is characterised by cramps and pain during menstruation due to heavy flow. Pain, cramps, and discomfort during periods are normal. However, excessive pain during periods is not normal and requires medication. Symptoms of dysmenorrhea include intense throbbing pain in the lower abdomen, dull, continuous aches, pain in the lower back and thighs, nausea, headache, and dizziness. The pain usually starts 1-3 days prior to the period, peaks one day before the period starts, and subsides 2-3days after the onset of the period.

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