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Written By Veda Maddala , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

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Manufacturer/Marketer :

Aretaeus Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About TRIGETROL TABLET

TRIGETROL TABLET belongs to a class of medicines called antidiabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance).

TRIGETROL TABLET is a combination of three antidiabetic drugs, namely: Glibenclamide, Metformin, and Rosiglitazone. Glibenclamide works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Rosiglitazone works by increasing the sensitivity of liver, muscle, and fat cells to insulin and enables cells to remove glucose from blood more effectively. Thereby, TRIGETROL TABLET helps to control blood sugar levels.

Take TRIGETROL TABLET as prescribed by your doctor. You are advised to take TRIGETROL TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhea, vomiting, headache, or low blood sugar. Most of these side effects of TRIGETROL TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to TRIGETROL TABLET or any other medicines, please tell your doctor. TRIGETROL TABLET is not recommended for children below 18 years of age. Avoid breastfeeding while taking TRIGETROL TABLET as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking TRIGETROL TABLET as it may harm an unborn baby. TRIGETROL TABLET should be used with caution in elderly patients. Avoid alcohol consumption with TRIGETROL TABLET as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking TRIGETROL TABLET .

Uses of TRIGETROL TABLET

Type 2 diabetes mellitus

Directions for Use

Take TRIGETROL TABLET with food to avoid stomach upset or take it as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Medicinal Benefits

TRIGETROL TABLET contains three antidiabetic drugs (Glibenclamide, Metformin, and Rosiglitazone) used in the treatment of type 2 diabetes. Glibenclamide stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood. Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Rosiglitazone increases the sensitivity of liver, muscle, and fat cells to insulin and enables cells to remove glucose from blood more effectively. Also, it decreases the amount of glucose produced by the liver and preserves the functioning of beta cells in the pancreas that produce insulin. Thereby, TRIGETROL TABLET helps to control blood sugar levels.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to TRIGETROL TABLET or any other medicines, please tell your doctor. TRIGETROL TABLET is not recommended for children. Avoid breastfeeding while taking TRIGETROL TABLET as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking TRIGETROL TABLET as it may harm the unborn baby. TRIGETROL TABLET should be used with caution in elderly patients. Avoid alcohol consumption with TRIGETROL TABLET as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking TRIGETROL TABLET . Take short, frequent meals and avoid prolonged fasting while taking TRIGETROL TABLET . Beware of symptoms of hypoglycemia (low blood sugar) which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and also consult your doctor. Make sure to carry these with you at all times, especially during long travels.

Drug-Drug Interactions

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MetforminIocetamic acid
Critical
MetforminIopromide
Critical

Drug-Drug Interactions

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MetforminIocetamic acid
Critical
How does the drug interact with Trigetrol Tablet:
Co-administration of Trigetrol Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Trigetrol Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Trigetrol Tablet:
Co-administration of Iopromide with Trigetrol Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Trigetrol Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIoglycamic acid
Critical
How does the drug interact with Trigetrol Tablet:
Co-administration of Ioglycamic acid with Trigetrol Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Trigetrol Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Trigetrol Tablet:
Co-administration of Iohexol with Trigetrol Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Trigetrol Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopamidol
Critical
How does the drug interact with Trigetrol Tablet:
Co-administration of Iopamidol with Trigetrol Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Trigetrol Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoversol
Critical
How does the drug interact with Trigetrol Tablet:
Co-administration of Ioversol with Trigetrol Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Trigetrol Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIoxitalamic acid
Critical
How does the drug interact with Trigetrol Tablet:
Co-administration of Trigetrol Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Trigetrol Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Trigetrol Tablet:
Co-administration of Iomeprol with Trigetrol Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Trigetrol Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIobenzamic acid
Critical
How does the drug interact with Trigetrol Tablet:
Co-administration of Trigetrol Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Trigetrol Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIocarmic acid
Critical
How does the drug interact with Trigetrol Tablet:
Co-administration of Trigetrol Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Trigetrol Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.
  • Maintain healthy body weight as obesity is also related to the onset of diabetes.
  • Maintain a low-fat and low-sugar diet. Replace carbohydrates-containing foods with whole grains, fruits, and vegetables as carbohydrates turn to sugars leading to high blood sugar.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

TRIGETROL TABLET contains Glibenclamide, Metformin and Rosiglitazone. Glibenclamide works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Rosiglitazone works by increasing the sensitivity of liver, muscle and fat cells to insulin and enables cells to remove glucose from blood more effectively. Thereby, TRIGETROL TABLET helps to control blood sugar levels.

TRIGETROL TABLET may increase the risk of low blood sugar levels, especially with alcohol intake, when you exercise more than usual, delay or miss snacks or meal. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.

You are not recommended to take TRIGETROL TABLET with levothyroxine as it may reduce the hypoglycemic (lowering blood sugar levels) effect of metformin. However, please consult a doctor before using TRIGETROL TABLET with other medicines.

In type 1 diabetes, the body doesn’t produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completed. In type 2 diabetes, though islet cells are working, the body doesn’t respond to insulin as the body becomes resistant to insulin.

You are not recommended to stop taking TRIGETROL TABLET on your own as discontinuing TRIGETROL TABLET suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking TRIGETROL TABLET , please consult your doctor so that alternative medicine may be prescribed.

Drug-Drug Interactions Checker List

  • BOSENTAN
  • INSULIN
  • SITAGLIPTIN
  • FUROSEMIDE
  • LEVOTHYROXINE
  • PREGABALIN

Special Advise

  • Regular blood tests are recommended while taking TRIGETROL TABLET to monitor blood sugar levels.

Disease/Condition Glossary

Type 2 diabetes: It is a chronic (long-lasting) condition that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. Symptoms of type 2 diabetes include frequent urination at night, increased thirst, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also includes nerve problems, kidney problems, the damaged retina of eyes or blindness, loss of limbs, sexual dysfunction, and increase the chance of heart attack or stroke.

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