Trustretin-25 Capsule 10's belongs to a group of medications called ‘retinoids’ used to treat psoriasis. Psoriasis is an autoimmune (immune system attacks healthy cells) skin disorder in which the skin becomes scaly, swollen, and itchy. It mostly affects the knee, elbows, scalp, and trunk. It is a lifelong condition, and treatment is given to remove affected skin cells and avoid flare-ups of the disease.

The Trustretin-25 Capsule 10's contains ‘Acitretin’, which belongs to the class of retinoids derived from vitamin A. It has anti-inflammatory and antiproliferative (decreases skin cell multiplication) properties. It works by slowing down the progression of the disease. It reduces the speed of skin cell growth and gradually clears the affected skin. It helps reduce the redness, scaling, and thickness of psoriasis rashes.

Trustretin-25 Capsule 10's is available in the form of tablets/capsules. You should take this medicine exactly as prescribed by your doctor. Trustretin-25 Capsule 10's may cause side-effects such as dry lips, peeling of the skin, especially the palms of the hands and soles of the feet, nose bleed, scaling and thinning of healthy skin, reddening of the skin, itching, burning sensation on the skin, sticky skin, hair loss, swelling and pain in the area around your nails, fragile nails, inflammation of the eye (conjunctivitis), increased thirst, and feeling cold. These side effects usually go away after discontinuing the treatment. However, if any of these side effects persist or worsen, inform your doctor immediately.

Do not take Trustretin-25 Capsule 10's if you are allergic to Acitretin or any other ingredients present in it. Trustretin-25 Capsule 10's should not be used in patients with liver or kidney failure, high cholesterol, and taking other medicines containing retinoids or supplements containing vitamin A. Trustretin-25 Capsule 10's should not be used in pregnant and breastfeeding women. Trustretin-25 Capsule 10's should be used with caution in children as it may affect growth and bone development. Trustretin-25 Capsule 10's may require dose adjustments when used in older people. Do not take alcohol, as it may increase the risk of side effects. Trustretin-25 Capsule 10's may cause vision problems, especially in the dark, so do not drive or operate heavy machinery if you notice any vision problems.

Trustretin-25 Capsule 10's contains ‘Acitretin’ that belongs to the class of ‘retinoids’. Retinoids are derived from vitamin A (retinol) and have anti-inflammatory and antiproliferative (reduces rapid skin cell division) action. Trustretin-25 Capsule 10's works by slowing down the progression of the diseases. Trustretin-25 Capsule 10's is used when the skin condition doesn’t improve with other conventional therapies. It can treat severe or extensive skin problems where the skin has become thick and scaly such as psoriasis. It can be long-term maintenance therapy for psoriasis patients. It can also be used in the treatment of other skin conditions such as ichthyosis (genetic skin disorder), pityriasis (skin rashes that appear as large spots on the chest, abdomen, or back), and lichen planus (itchy, non-infectious rashes on arms and legs).

• Dry lips
• Peeling of the skin, especially the palms of the hands and soles of the feet
• Nose bleed
• Scaling and thinning of healthy skin
• Reddening of the skin
• Itching
• Burning sensation on the skin
• Sticky skin
• Hair loss
• Swelling and pain in the area around your nails
• Fragile nails
• Inflammation of the eye (conjunctivitis)
• Increased thirst
• Feeling cold

Trustretin-25 Capsule 10's should not be used in pregnant and breastfeeding women. So, the doctor may advise you to take a pregnancy test before using Trustretin-25 Capsule 10's. You should also take effective and reliable contraception (such as an intrauterine device, contraceptive implant, or contraceptive pill and condom) during the treatment and after three years of discontinuing the treatment. You should take reliable contraception even if your periods are not regular or not sexually active unless your doctor decides that this is unnecessary. You should not donate blood during the treatment and after three years of discontinuing the treatment. Trustretin-25 Capsule 10's should be used in caution in patients with diabetes as it can alter blood glucose levels. Trustretin-25 Capsule 10's may cause vision problems, especially in the night-time. So, inform your doctor if you notice vision problems. Do not wear contact lenses during the treatment as the Trustretin-25 Capsule 10's may cause dry eyes. Trustretin-25 Capsule 10's may increase skin sensitivity, so avoid going in strong sunlight and using a sunbed. Trustretin-25 Capsule 10's may affect your mood, so inform your doctor if you have mental health problems like depression. Also, inform your doctor if you notice drastic mood changes while using Trustretin-25 Capsule 10's.

Drug-Drug Interactions: Trustretin-25 Capsule 10's should not be used in patients taking other retinoids or supplements containing vitamin A. Trustretin-25 Capsule 10's may interact with an antibiotic (tetracycline) and cause increased pressure in the brain. It may interact with a medicine used to treat cancer, psoriasis, or rheumatic diseases (methotrexate) and cause liver damage. It may decrease the efficacy of an antiepileptic drug (phenytoin). It may also interact with a mini-pill (a type of birth control pill with low doses of progesterone).

Drug-Food Interactions: Do not consume alcohol while using Trustretin-25 Capsule 10's as it may increase the risk of side effects.

Drug-Disease Interactions: Trustretin-25 Capsule 10's should be used with caution in patients with liver or kidney failure, high cholesterol, overweight, alcoholic abuse, diabetes, and mental health problems.

• TETRACYCLINE
• METHOTREXATE
• PHENYTOIN

• Use mild soap while taking baths and prefer warm baths.
• Do not scratch or pick your skin to avoid infecting the affected area.
• Avoid harsh products on your skin.
• Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
• Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
• Avoid consuming foods with excess sugar, as it may flare up inflammation.
• Include fruits, vegetables, whole grains, healthy fats, and fish in your diet.
• Avoid getting in contact with harsh soaps, detergents, and rough fabrics. 

• Growth and bone development should be regularly monitored if the Trustretin-25 Capsule 10's is given to children.
• Patients with diabetes are advised to monitor blood glucose levels while using this medicine regularly.
• Patients with high cholesterol should regularly monitor fat levels in the blood while using this medicine.
• Your doctor may also check liver function before, during, and after three weeks of discontinuing Trustretin-25 Capsule 10's, as this medicine may affect liver function.
• If Trustretin-25 Capsule 10's is prescribed for the long-term, your doctor may perform an x-ray of certain bones once a year, as this medicine may affect bone development.
• Trustretin-25 Capsule 10's may cause birth defects, so women planning for pregnancy are advised to the regular pregnancy test and should not become pregnant for the next three years after using Trustretin-25 Capsule 10's.

Psoriasis: Psoriasis is an autoimmune skin disease characterized by red, itchy, and scaly rashes. It occurs when the immune system mistakenly attacks healthy skin cells. In this condition, skin cells grow and build up rapidly, resulting in scaly rashes, mostly on the knees, elbows, scalp, and trunk. Stress and cold can act as triggers for this disease. It is a chronic disease and doesn’t have a permanent cure. Treatment is given to control the disease and prevent flare-ups.