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  3. UNICARB 450MG INJECTION

UNICARB 450MG INJECTION , Pack of 1
UNICARB 450MG INJECTION , Pack of 1
UNICARB 450MG INJECTION , Pack of 1
Written By Bayyarapu Mahesh Kumar , M Pharmacy
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Whats That

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Composition :

CARBOPLATIN-450MG

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About UNICARB 450MG INJEC

UNICARB 450MG INJEC belongs to a group of anti-cancer medicines used for the treatment of ovarian cancer and small-cell lung cancer. It may sometimes be used to treat other cancers. Cancer forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

UNICARB 450MG INJEC contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

UNICARB 450MG INJEC is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection. You may experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses and electrolyte disturbances. Most of these side effects of UNICARB 450MG INJEC do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking UNICARB 450MG INJEC for as long as your doctor has prescribed. Do not stop the UNICARB 450MG INJEC midway. Talk to your doctor before taking UNICARB 450MG INJEC if you have severe allergic reactions to UNICARB 450MG INJEC or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. UNICARB 450MG INJEC should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking UNICARB 450MG INJEC if you are pregnant or breastfeeding because this UNICARB 450MG INJEC can cause harmful effects on the unborn baby. Both women and men using this UNICARB 450MG INJEC should use birth control to avoid pregnancy.

Uses of UNICARB 450MG INJEC

Ovarian cancer and Small cell lung cancer

Directions for Use

Parenteral: UNICARB 450MG INJEC will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

UNICARB 450MG INJEC contains 'Carboplatin' which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or with other chemotherapy drugs depending on your cancer type.

Storage

Keep UNICARB 450MG INJEC out of the sight and reach of children.
Side effects of Unicarb 450mg Injection
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Avoid loud noises using ear protection aids like earplugs.
  • Take breaks from noisy environments.
  • Consult the doctor if you experience hearing problems; the doctor will monitor your condition and recommend suitable treatment measures.
  • Drink more fluids as dehydration can decrease blood flow to kidneys and increase BUN levels.
  • Eat less protein and stop protein supplements as high protein diet may increase BUN levels.
  • Severe cases may require kidney transplant or dialysis.

Drug Warnings

UNICARB 450MG INJEC should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking UNICARB 450MG INJEC. To treat your condition effectually, continue taking UNICARB 450MG INJEC for as long as your doctor has prescribed. Do not stop the UNICARB 450MG INJEC midway. Talk to your doctor before taking UNICARB 450MG INJEC if you have severe allergic reactions to UNICARB 450MG INJEC or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. UNICARB 450MG INJEC should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking UNICARB 450MG INJEC if you are pregnant or breastfeeding because this UNICARB 450MG INJEC can cause harmful effects on the unborn baby. Both women and men using this UNICARB 450MG INJEC should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during UNICARB 450MG INJEC treatment and appropriate until recovery is achieved.

Drug-Drug Interactions

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CarboplatinSorafenib
Critical
CarboplatinTofacitinib
Severe

Drug-Drug Interactions

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CarboplatinSorafenib
Critical
How does the drug interact with Unicarb 450mg Injection:
Co-administration of Sorafenib with Unicarb 450mg Injection can increase the risk or severity of serious side effects.

How to manage the interaction:
Taking Sorafenib with Unicarb 450mg Injection together is not recommended as it can cause an interaction, consult a doctor before taking it. However if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without consulting a doctor.
CarboplatinTofacitinib
Severe
How does the drug interact with Unicarb 450mg Injection:
Co-administration of Unicarb 450mg Injection with tofacitinib can increase the risk of serous infections.

How to manage the interaction:
Although there is an interaction, Unicarb 450mg Injection can be taken with tofacitinib if prescribed by the doctor. However, If you experience fever, chills, diarrhea, sore throat, muscular pains, breathing difficulty, blood in phlegm(mucous secretion), red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting your doctor.
CarboplatinLeflunomide
Severe
How does the drug interact with Unicarb 450mg Injection:
Co-administration of leflunomide with Unicarb 450mg Injection can increase the risk of infections.

How to manage the interaction:
Co-administration of Unicarb 450mg Injection with leflunomide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm(mucous secretion), red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting your doctor.
CarboplatinCertolizumab
Severe
How does the drug interact with Unicarb 450mg Injection:
Using Unicarb 450mg Injection with Certolizumab can increase the risk of developing serious infections.

How to manage the interaction:
Taking Unicarb 450mg Injection with Certolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CarboplatinNatalizumab
Severe
How does the drug interact with Unicarb 450mg Injection:
Taking Unicarb 450mg Injection with Natalizumab can increase the risk of developing serious infections. Particularly, progressive multifocal leukoencephalopathy(a rare but serious viral infection of the brain).

How to manage the interaction:
Taking Unicarb 450mg Injection with Natalizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, weakness on one side of the body, clumsiness of legs and hands, eye problems, confusion, or changes in thinking, memory and personality, consult a doctor. Do not stop using any medications without a doctor's advice.
CarboplatinTopotecan
Severe
How does the drug interact with Unicarb 450mg Injection:
When Unicarb 450mg Injection is used with topotecan, it may increase the risk of side effects.

How to manage the interaction:
Co-administration of Unicarb 450mg Injection with clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting your doctor.
CarboplatinAdalimumab
Severe
How does the drug interact with Unicarb 450mg Injection:
Using Adalimumab with Unicarb 450mg Injection can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Unicarb 450mg Injection and Adalimumab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CarboplatinDeferiprone
Severe
How does the drug interact with Unicarb 450mg Injection:
Using Unicarb 450mg Injection with Deferiprone, can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Unicarb 450mg Injection and Deferiprone, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CarboplatinFingolimod
Severe
How does the drug interact with Unicarb 450mg Injection:
Using Unicarb 450mg Injection with Fingolimod can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Unicarb 450mg Injection and Fingolimod, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CarboplatinCidofovir
Severe
How does the drug interact with Unicarb 450mg Injection:
Taking cidofovir with Unicarb 450mg Injection can increase the risk of kidney problems.

How to manage the interaction:
Although taking Unicarb 450mg Injection and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience loss of hunger, increased or decreased urination, swelling, shortness of breath, bone pain, muscle cramps, irregular heart rhythm, consult a doctor immediately. It is advised to wait at least for 7 days after stopping Unicarb 450mg Injection, before taking Cidofovir. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Side Effects of UNICARB 450MG INJEC

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Hair loss and numbness
  • Tingling
  • Burning
  • Pain in the hands or feet
  • Nephrotoxicity at high doses
  • Electrolyte disturbances
  • Thrombocytopenia (low blood platelet count)
  • Peripheral neuropathy (nerves malfunction)
  • Leukopenia (low white blood cell count)

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

UNICARB 450MG INJEC Substitute

Substitutes safety advice

Product Substitutes

Drug-Diseases Interactions

verifiedApollotooltip
CARBOPLATIN-450MGOther and unspecified infectious diseases
Moderate
CARBOPLATIN-450MGOther disorders of kidney and ureter, not elsewhere classified
Moderate

Drug-Diseases Interactions

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CARBOPLATIN-450MGOther and unspecified infectious diseases
Moderate
How does the disease interact with Unicarb 450mg Injection:
Antineoplastic drugs regularly can, to variable degrees, promote myelosuppression due to their cytotoxic effects on rapidly growing tissues.

How to manage the interaction:
If you experience any signs or symptoms suggesting infection such as fever, sore throat, or local infection during antineoplastic therapy, immediately consult your doctor. Close clinical monitoring of hematopoietic function is recommended.
CARBOPLATIN-450MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Unicarb 450mg Injection:
The kidney is the main organ used to remove Unicarb 450mg Injection. Patients with a creatinine clearance of less than 60 mL/min had lower total body and renal clearance of Unicarb 450mg Injection.

How to manage the interaction:
If you have any kidney related problems, do not forget to mention it to your doctor, a close monitoring is required.
CARBOPLATIN-450MGHaemorrhage, not elsewhere classified
Mild
How does the disease interact with Unicarb 450mg Injection:
Patients who have substantial bleeding should not use Unicarb 450mg Injection. Both severe myelosuppression and dose-dependent thrombocytopenia are brought on by Unicarb 450mg Injection.

How to manage the interaction:
The use of Unicarb 450mg Injection is not advisable if you have significant bleeding. If you experience any signs or symptoms suggesting bleeding such as petechiae, purpura, epistaxis, hemoptysis, hematuria, and melena, consult your doctor. Close clinical monitoring of hematopoietic function is recommended.

FAQs

UNICARB 450MG INJEC contains 'Carboplatin'. Carboplatin works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.

Yes, UNICARB 450MG INJEC can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.

UNICARB 450MG INJEC should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.

Before you receive treatment with UNICARB 450MG INJEC, tell your doctor about all of your medical conditions. You should not receive UNICARB 450MG INJEC if you are allergic to carboplatin or any contents in UNICARB 450MG INJEC. It should not be employed in patients with severe bone marrow depression or significant bleeding.

If not given an inappropriate dose, UNICARB 450MG INJEC can cause toxic effects, although not everyone gets it. So, UNICARB 450MG INJEC is prescribed by a doctor experienced in the use of medications to treat cancer only.

Avoid taking UNICARB 450MG INJEC if you are pregnant because UNICARB 450MG INJEC can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of UNICARB 450MG INJEC.

Drug-Drug Interactions Checker List

  • PEMETREXED
  • GEMCITABINE
  • PEGFILGRASTIM
  • PACLITAXEL
  • PANTOPRAZOLE
  • AMIKACIN
  • GENTAMICIN
  • KANAMYCIN
  • STREPTOMYCIN
  • TOBRAMYCIN
  • DOCETAXEL

Special Advise

  • Peripheral blood counts should be frequently monitored during carboplatin treatment and, when appropriate, until recovery is achieved.
  • UNICARB 450MG INJEC should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking UNICARB 450MG INJEC.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. UNICARB 450MG INJEC may make your skin sensitive to sunlight.

Disease/Condition Glossary

Ovarian cancer: Cancer that forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

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