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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Aug 20, 2024 | 1:15 PM IST

About Uniphos 1000 Injection 1's

Uniphos 1000 Injection 1's belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt's lymphoma, leukaemia,  neuroblastoma, retinoblastoma, adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma, small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Additionally, Uniphos 1000 Injection 1's is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
Uniphos 1000 Injection 1's contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, Uniphos 1000 Injection 1's helps treat cancer. Uniphos 1000 Injection 1's suppresses the body's immune system and helps treat nephrotic syndrome.
 
In some cases, Uniphos 1000 Injection 1's may cause nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss). You are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding. Uniphos 1000 Injection 1's may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Uniphos 1000 Injection 1's

Malignant diseases (cancer), nephrotic syndrome (kidney disease)

Medicinal Benefits

Uniphos 1000 Injection 1's belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease (cancer of the lymphatic system), mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma (cancer of plasma cells), Burkitt's lymphoma, leukaemia (blood cancer), neuroblastoma (cancer commonly found in the adrenal glands), retinoblastoma (eye cancer), adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma (cancer in and around the bones), small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Uniphos 1000 Injection 1's works by stopping or slowing the growth of cancer cells in the body. Thereby, Uniphos 1000 Injection 1's helps treat cancer. Additionally, Uniphos 1000 Injection 1's is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. Uniphos 1000 Injection 1's suppresses the body's immune system, thereby helping treat nephrotic syndrome.

Directions for Use

Uniphos 1000 Injection 1's will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Uniphos 1000 Injection 1's

  • Nausea
  • Vomiting
  • Stomatitis (inflamed and sore mouth)
  • Weakness
  • Malaise (general discomfort)
  • Fever
  • Leukopenia (low white blood cell count)
  • Alopecia (hair loss)

Drug Warnings

Do not take Uniphos 1000 Injection 1's if you are allergic to any of its components. Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow/obstruction, liver or kidney problems, or urinary or respiratory symptoms. Consult your doctor if you are pregnant or breastfeeding. Uniphos 1000 Injection 1's may cause myelosuppression, immunosuppression, bone marrow failure, and infections; consult your doctor if you have any concerns.

Drug Interactions

Drug-Drug Interactions: Uniphos 1000 Injection 1's may have interaction with protease inhibitors, ACE inhibitors, immunomodulators (natalizumab), chemotherapy agents (paclitaxel), thiazide diuretics, anti-HIV (zidovudine), antiarrhythmics (amiodarone), anti-fungal (amphotericin B), NSAID (indomethacin), immunosuppressant (azathioprine), alkylating agents (busulfan).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow or obstruction.

Drug-Drug Interactions Checker List

  • NATALIZUMAB
  • PACLITAXEL
  • ZIDOVUDINE
  • AMIODARONE
  • AMPHOTERICIN B
  • INDOMETHACIN
  • AZATHIOPRINE
  • BUSULFAN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your food.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Special Advise

  • Monitoring of complete blood count whilst on treatment with Uniphos 1000 Injection 1's is advised.
  • Women of childbearing potential must use highly effective contraception during treatment and for up to 1 year after the last dose.
  • Male patients who are sexually active with a female partner of child-bearing potential must use condoms during treatment and for up to 6 months after the last dose.

Disease/Condition Glossary

Cancer: It occurs due to mutations in genes that regulate cell growth. The mutations cause the cells to divide and multiply in an uncontrolled manner leading to the formation of tumours. The most common cancer treatment methods are surgery, chemotherapy, radiotherapy, bone marrow (stem cell) transplantation, immunotherapy and targeted drug therapy.

Nephrotic syndrome: It is a kidney disorder in which the body excretes too much protein in the urine. Symptoms include foamy urine, weight gain, and swelling around the eyes and in the ankles and feet.

About Uniphos 1000 Injection 1's

Uniphos 1000 Injection 1's belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt's lymphoma, leukaemia,  neuroblastoma, retinoblastoma, adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma, small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Additionally, Uniphos 1000 Injection 1's is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
Uniphos 1000 Injection 1's contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, Uniphos 1000 Injection 1's helps treat cancer. Uniphos 1000 Injection 1's suppresses the body's immune system and helps treat nephrotic syndrome.
 
In some cases, Uniphos 1000 Injection 1's may cause nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss). You are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding. Uniphos 1000 Injection 1's may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Non returnable*
COD available

Online payment accepted

Prescription drug

Whats That

tooltip
Non returnable*
COD available

Online payment accepted

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Uniphos 1000 Injection 1's

Malignant diseases (cancer), nephrotic syndrome (kidney disease)

Medicinal Benefits

Uniphos 1000 Injection 1's belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease (cancer of the lymphatic system), mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma (cancer of plasma cells), Burkitt's lymphoma, leukaemia (blood cancer), neuroblastoma (cancer commonly found in the adrenal glands), retinoblastoma (eye cancer), adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma (cancer in and around the bones), small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Uniphos 1000 Injection 1's works by stopping or slowing the growth of cancer cells in the body. Thereby, Uniphos 1000 Injection 1's helps treat cancer. Additionally, Uniphos 1000 Injection 1's is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. Uniphos 1000 Injection 1's suppresses the body's immune system, thereby helping treat nephrotic syndrome.

Side Effects of Uniphos 1000 Injection 1's

  • Nausea
  • Vomiting
  • Stomatitis (inflamed and sore mouth)
  • Weakness
  • Malaise (general discomfort)
  • Fever
  • Leukopenia (low white blood cell count)
  • Alopecia (hair loss)

Directions for Use

Uniphos 1000 Injection 1's will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Uniphos 1000 Injection 1's if you are allergic to any of its components. Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow/obstruction, liver or kidney problems, or urinary or respiratory symptoms. Consult your doctor if you are pregnant or breastfeeding. Uniphos 1000 Injection 1's may cause myelosuppression, immunosuppression, bone marrow failure, and infections; consult your doctor if you have any concerns.

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions Checker List

  • NATALIZUMAB
  • PACLITAXEL
  • ZIDOVUDINE
  • AMIODARONE
  • AMPHOTERICIN B
  • INDOMETHACIN
  • AZATHIOPRINE
  • BUSULFAN

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your food.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Special Advise

  • Monitoring of complete blood count whilst on treatment with Uniphos 1000 Injection 1's is advised.
  • Women of childbearing potential must use highly effective contraception during treatment and for up to 1 year after the last dose.
  • Male patients who are sexually active with a female partner of child-bearing potential must use condoms during treatment and for up to 6 months after the last dose.

Disease/Condition Glossary

Cancer: It occurs due to mutations in genes that regulate cell growth. The mutations cause the cells to divide and multiply in an uncontrolled manner leading to the formation of tumours. The most common cancer treatment methods are surgery, chemotherapy, radiotherapy, bone marrow (stem cell) transplantation, immunotherapy and targeted drug therapy.

Nephrotic syndrome: It is a kidney disorder in which the body excretes too much protein in the urine. Symptoms include foamy urine, weight gain, and swelling around the eyes and in the ankles and feet.

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