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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

About Valprol Vial Kit 5 ml

Valprol Vial Kit 5 ml belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Valprol Vial Kit 5 ml is also used to treat bipolar disorder. Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain leading to seizures, unusual behavior, and loss of awareness. Bipolar disorder is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. 
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Valprol Vial Kit 5 ml contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Valprol Vial Kit 5 ml increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 
 
Valprol Vial Kit 5 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as sleepiness, dizziness, nausea, headache, and asthenia (weakness). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you are of childbearing age, use effective contraception while on treatment with Valprol Vial Kit 5 ml. Inform your doctor before taking Valprol Vial Kit 5 ml if you are pregnant or breastfeeding. Do not drive or operate machinery as Valprol Vial Kit 5 ml may cause sleepiness and dizziness. Avoid consuming alcohol along with Valprol Vial Kit 5 ml as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

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Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Int-Intas Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Valprol Vial Kit 5 ml

Epilepsy/seizures, Bipolar disorder

Medicinal Benefits

Valprol Vial Kit 5 ml belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Valprol Vial Kit 5 ml decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Additionally, Valprol Vial Kit 5 ml is also used to treat bipolar disorder. Valprol Vial Kit 5 ml increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 

Side Effects of Valprol Vial Kit 5 ml

  • Somnolence (sleepiness)
  • Dizziness
  • Nausea
  • Headache
  • Asthenia (weakness)
  • Paresthesia (prickling or burning sensation)

Directions for Use

Valprol Vial Kit 5 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Valprol Vial Kit 5 ml if you are allergic to any of its contents, if you have urea cycle problems, mitochondrial disorders, or hepatic disease/dysfunction. Inform your doctor if you have/had liver problems, porphyria (blood disorder), diabetes, immune system disorder, bleeding problems, systemic lupus erythematosus (a rare skin condition), or kidney problems. Valprol Vial Kit 5 ml may cause hepatotoxicity (liver damage); consult your doctor if you experience symptoms such as weakness, facial swelling, vomiting, malaise (general discomfort), lethargy (lack of energy or enthusiasm), and anorexia (eating disorder). Valprol Vial Kit 5 ml may also cause pancreatitis (inflammation of the pancreas); consult your doctor if you experience symptoms such as abdominal pain, vomiting, nausea, and/or anorexia (eating disorder).

Therapeutic Class

ANTICONVULSANT

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateErtapenem
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valprol Vial Kit 5 ml:
Combining Sodium phenylbutyrate and Valprol Vial Kit 5 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valprol Vial Kit 5 ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Valprol Vial Kit 5 ml:
The combined use of Ertapenem and Valprol Vial Kit 5 ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valprol Vial Kit 5 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Valprol Vial Kit 5 ml:
Co-administration of Valprol Vial Kit 5 ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valprol Vial Kit 5 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Valprol Vial Kit 5 ml:
Co-administration of Lithium with Valprol Vial Kit 5 ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valprol Vial Kit 5 ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Valprol Vial Kit 5 ml:
Co-administration of Ketamine and Valprol Vial Kit 5 ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valprol Vial Kit 5 ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Valprol Vial Kit 5 ml:
Using buprenorphine together with Valprol Vial Kit 5 ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valprol Vial Kit 5 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Valprol Vial Kit 5 ml:
Co-administration of Leflunomide and Valprol Vial Kit 5 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valprol Vial Kit 5 ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Valprol Vial Kit 5 ml:
Co-administration of Teriflunomide and Valprol Vial Kit 5 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valprol Vial Kit 5 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Valprol Vial Kit 5 ml:
Co-administration of Vorinostat with Valprol Vial Kit 5 ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valprol Vial Kit 5 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Valprol Vial Kit 5 ml:
Co-administration of Meropenam and Valprol Vial Kit 5 ml together can reduce the effect of Valprol Vial Kit 5 ml.

How to manage the interaction:
Co-administration of Meropenam and Valprol Vial Kit 5 ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • TOPIRAMATE
  • LAMOTRIGINE
  • FELBAMATE
  • ETHOSUXIMIDE
  • WARFARIN
  • ZIDOVUDINE
  • DIAZEPAM
  • AMITRIPTYLINE
  • NORTRIPTYLINE
  • RIFAMPICIN

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well; get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan that helps those around you know what to do.
  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Special Advise

  • Contact your doctor immediately if you develop suicidal thoughts such as harming or killing yourself.
  • Regular tests such as serum liver tests, platelet count, coagulation tests, and ammonia level tests are advised whilst on treatment with Valprol Vial Kit 5 ml.
  • If you are of childbearing age, use effective contraception during the entire treatment with Valprol Vial Kit 5 ml.
  • Consult your doctor immediately if you become pregnant while on treatment with Valprol Vial Kit 5 ml.

Author Details

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Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumour, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. Symptoms of manic episodes include high energy, loss of touch with reality, and reduced need for sleep. Symptoms of depressive episodes include low motivation, low energy, and loss of interest in daily life.

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