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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Manufacturer/Marketer :

Ventus Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Vermidol-Xl Tablet

Vermidol-Xl Tablet is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, and bone and joint pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis, also known as joint inflammation, is the tenderness and swelling of the joints. Symptoms include swelling, pain, and stiffness. 

Vermidol-Xl Tablet consists of Diclofenac (Diclofenac Potassium), Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes. Thus, it reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reduces swelling and inflammation.

Vermidol-Xl Tablet should be taken as prescribed by your doctor.  Sometimes it may cause certain common side effects such as nausea, vomiting, stomach pain, loss of appetite, indigestion, and diarrhea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Vermidol-Xl Tablet may cause drowsiness and dizziness, so drive with caution. Vermidol-Xl Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with Vermidol-Xl Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any interactions. It is advised not to take more than the prescribed dose of medicine and for a longer period. 

Uses of Vermidol-Xl Tablet

Pain and inflammation associated with musculoskeletal and joint disorders.

Directions for Use

Take Vermidol-Xl Tablet with food to prevent stomach upset. Swallow Vermidol-Xl Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Vermidol-Xl Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol, and Trypsin chymotrypsin. Vermidol-Xl Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Diclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug) and Paracetamol is an analgesic. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes, thereby reducing mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin is a combination of enzymes that breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation by increasing the blood supply at the affected area.

Storage

Keep Vermidol-Xl Tablet out of the sight and reach of children.

Drug Warnings

Avoid taking Vermidol-Xl Tablet if you are allergic to any of its contents; if you have/had severe heart problems, active or recurring peptic ulcer, gastrointestinal perforation, bleeding problems, inflammation of intestines, or severe liver or kidney impairment. Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, angina, bowel problems, a habit of smoking, or liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Stop taking Vermidol-Xl Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. This medicine is not recommended for use in children as safety is not established. It is advised not to take more than the prescribed dose of Vermidol-Xl Tablet for a prolonged period.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Vermidol-Xl Tablet:
Co-administration of Vermidol-Xl Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Vermidol-Xl Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Vermidol-Xl Tablet:
Taking Vermidol-Xl Tablet with warfarin may, increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Vermidol-Xl Tablet and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vermidol-Xl Tablet:
Co-administration of methotrexate with Vermidol-Xl Tablet can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Vermidol-Xl Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with Vermidol-Xl Tablet:
Co-administration of Vermidol-Xl Tablet with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Vermidol-Xl Tablet and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Vermidol-Xl Tablet:
Concomitant use of Vermidol-Xl Tablet with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking Vermidol-Xl Tablet with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Vermidol-Xl Tablet:
Coadministration of Vermidol-Xl Tablet with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Vermidol-Xl Tablet and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacValdecoxib
Severe
How does the drug interact with Vermidol-Xl Tablet:
Taking Valdecoxib with Vermidol-Xl Tablet may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Vermidol-Xl Tablet and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
How does the drug interact with Vermidol-Xl Tablet:
Co-administration of Vermidol-Xl Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Vermidol-Xl Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Vermidol-Xl Tablet:
Co administration of Vermidol-Xl Tablet with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Vermidol-Xl Tablet and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacVorapaxar
Severe
How does the drug interact with Vermidol-Xl Tablet:
Taking Vermidol-Xl Tablet with Vorapaxar can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Vermidol-Xl Tablet and Vorapaxar, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

Side Effects of Vermidol-Xl Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhea
  • Indigestion
  • Loss of appetite
  • Heartburn

Habit Forming

No

Therapeutic Class

ANALGESICS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Vermidol-Xl Tablet contains Diclofenac, Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.

Do not take any other medicines for pain relief, such as NSAIDs along with Vermidol-Xl Tablet , unless prescribed by a doctor, as it might increase the risk of side effects.

Avoid exceeding the dose and duration advised by the doctor. Taking more than the daily dose of Vermidol-Xl Tablet might cause serious liver damage or allergic reactions like rash, difficulty breathing, and swelling of the face, throat, and mouth. Therefore, Vermidol-Xl Tablet should not be taken for longer durations unless prescribed by the doctor.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • CLOPIDOGREL
  • CHLORAMPHENICOL
  • DIGOXIN
  • METHOTREXATE
  • ZIDOVUDINE
  • CICLOSPORIN
  • WARFARIN

Special Advise

 

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints, or other body parts. Ankylosing spondylitis symptoms include decreased flexibility which usually leads to a hunched-forward posture and pain in the back and joints.

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Vermidol-Xl Tablet as it may increase drowsiness. It may also increase the risk of stomach bleeding.

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Pregnancy

Caution

Inform your doctor if you are pregnant or planning pregnancy before taking Vermidol-Xl Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding before taking Vermidol-Xl Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Vermidol-Xl Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have liver problems. Dose adjustment may be needed. Vermidol-Xl Tablet is not recommended for patients with severe hepatic impairment.

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Kidney

Caution

Please consult your doctor if you have kidney impairment. Dose adjustment may be needed. Vermidol-Xl Tablet is not recommended for patients with severe renal impairment.

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Children

Unsafe

Vermidol-Xl Tablet is not recommended for children as safety and effectiveness have not been established.

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