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Reviewed By Sureshvarma D , MPharma
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Manufacturer/Marketer

Natco Pharma Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About VORIZOL 50MG TABLET

VORIZOL 50MG TABLET belongs to the class of medicines known as 'antifungals' used to treat a broad range of infections caused due to fungi and yeast. A fungal infection is caused when a fungus invades and affects any part of the body, including the mouth, throat, esophagus, lungs, bladder, genital area and blood.

VORIZOL 50MG TABLET contains ‘Voriconazole’ that kills or prevents fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, which interferes with the fungal cell membrane's formation. As a result, fungal or yeast cells get killed, or their growth is minimized. 

Take VORIZOL 50MG TABLET as prescribed by your doctor. You are advised to take VORIZOL 50MG TABLET for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience certain common side effects such as vomiting, headache, nausea, abnormal liver function tests, rash, slow heart rate, and altered vision. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Do not take VORIZOL 50MG TABLET if you have had an allergic reaction VORIZOL 50MG TABLET or any of its ingredients. VORIZOL 50MG TABLET is associated with liver toxicity, including fatalities in patients with other serious underlying diseases. VORIZOL 50MG TABLET is a pregnancy category D drug, so it should not be taken by breastfeeding and pregnant women. Exposure to sunlight should be avoided while taking $Name as it makes you sensitive to the sun's UV rays or use a high sun protection factor (SPF) while going out. Antacid should be taken at 2 hours after taking VORIZOL 50MG TABLET.

Uses of VORIZOL 50MG TABLET

Fungal infections

Directions for Use

Tablet: Take VORIZOL 50MG TABLET with or without food or as directed by your physician. Swallow the whole tablet with a glass of water. Do not crush, chew or break it. Oral suspension/Syrup: Shake the oral suspension well before use, and always use a measuring device for intake.

Medicinal Benefits

VORIZOL 50MG TABLET belongs to the class of medicines known as 'antifungal' containing Voriconazole, used to treat a broad range of infections caused due to fungi and yeast. It treats various fungal infections like invasive aspergillosis (fungal infection in the lungs), esophageal candidiasis (white patching in the mouth and throat) and candidemia (a fungal infection in the blood). It is also used to treat certain fungal infections when other medications do not work for certain patients. It works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, interfering with the fungal cell membrane's formation. As a result, fungal or yeast cells get killed, or their growth is minimized.

Storage

Store in a cool and dry place away from sunlight

Side Effects of VORIZOL 50MG TABLET

  • Vomiting
  • Headache
  • Nausea
  • Abnormal liver function tests
  • Rash
  • Sinus infections
  •  Low numbers of white and red blood cells
  • Slow heart rate
  • Altered vision
  • Low blood sugar
  • Depression, hallucinations

Drug Warnings

Do not take VORIZOL 50MG TABLET if you have had an allergic reaction VORIZOL 50MG TABLET or any of its ingredients. VORIZOL 50MG TABLET is associated with liver toxicity, including fatalities in patients with other serious underlying diseases. If you are suffering from liver disease, the doctor will lower the dose, and a regular liver function test will be done. VORIZOL 50MG TABLET is a pregnancy category D drug, so it should not be taken in breastfeeding and pregnant women. If you are suffering from a heart problem like an irregular heartbeat, slow heart rate or abnormality in ECG (electrocardiogram), please inform your doctor before starting VORIZOL 50MG TABLET. Exposure to sunlight should be avoided while taking $Name as it makes you sensitive to the sun's UV rays or use a high sun protection factor (SPF) while going out. Antacid should be taken at 2 hours after taking VORIZOL 50MG TABLET.

Drug-Drug Interactions

verifiedApollotooltip
VoriconazoleEfavirenz
Critical
VoriconazoleConivaptan
Critical

Drug-Drug Interactions

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VoriconazoleEfavirenz
Critical
How does the drug interact with Vorizol 50mg Tablet:
Coadministration of Vorizol 50mg Tablet with Efavirenz can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Efavirenz can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
VoriconazoleConivaptan
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using Conivaptan together with Vorizol 50mg Tablet may significantly increase the blood levels and effects of conivaptan.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Conivaptan is not recommended, please consult your doctor before taking it. Call a doctor if you experience difficulty swallowing, trouble speaking, trouble controlling body movements. Do not stop using any medications without talking to a doctor.
VoriconazoleZiprasidone
Critical
How does the drug interact with Vorizol 50mg Tablet:
Co-administration of Vorizol 50mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Vorizol 50mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
VoriconazoleIvabradine
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using ivabradine together with Vorizol 50mg Tablet may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Vorizol 50mg Tablet together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
VoriconazolePhenobarbital
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using Vorizol 50mg Tablet together with Phenobarbital may significantly reduce the blood levels of Vorizol 50mg Tablet.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Phenobarbital is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
VoriconazoleMethylergometrine
Critical
How does the drug interact with Vorizol 50mg Tablet:
Coadministration of Methylergometrine with Vorizol 50mg Tablet may increase the blood level of Methylergometrine.

How to manage the interaction:
Although Methylergometrine with Vorizol 50mg Tablet can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
VoriconazoleCarbamazepine
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using Vorizol 50mg Tablet together with Carbamazepine may significantly reduce the blood levels of Vorizol 50mg Tablet.

How to manage the interaction:
Taking Carbamazepine with Vorizol 50mg Tablet is not recommended, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
VoriconazoleAlfuzosin
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using alfuzosin together with Vorizol 50mg Tablet may significantly increase the blood levels and effects of alfuzosin.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Alfuzosin is not recommended, please consult a doctor before taking it. Call a doctor if you experience dizziness, headache, nasal congestion, or heart palpitation. Do not stop using any medications without talking to a doctor.
VoriconazoleQuinidine
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using Quinidine together with Vorizol 50mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Quinidine is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
VoriconazoleSimvastatin
Critical
How does the drug interact with Vorizol 50mg Tablet:
Taking Vorizol 50mg Tablet and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects (liver damage and rhabdomyolysis - involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Vorizol 50mg Tablet and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if a doctor advises. However, if you experience muscle pain, fever or dark-colored urine, vomiting, and yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • In wet places such as changing rooms and gym showers, don’t walk barefoot to prevent fungal infections.
  • Do not scratch the affected skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.
  • Avoid taking VORIZOL 50MG TABLET (oral form) with foods containing chocolate and caffeine, such as cocoa beans, tea, coffee, cola and energy drinks, as it may increase the adverse effects of caffeine.
  • Avoid alcohol intake with VORIZOL 50MG TABLET (oral form) as it may cause adverse effects and increase the risk of liver damage.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcohol and switches to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

VORIZOL 50MG TABLET Substitute

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PIMOZIDE
  • QUETIAPINE
  • REBOXETINE
  • ERGOTAMINE
  • DIHYDROERGOTAMINE
  • CARBAMAZEPINE
  • RIFABUTIN
  • SIROLIMUS
  • RITONAVIR
  • CISAPRIDE
  • RIFAMPICIN

Special Advise

  • Liver function tests should be monitored regularly while taking VORIZOL 50MG TABLET.
  • Wear a strong SPF while going out in the sun.

Disease/Condition Glossary

Fungal infection: It occurs when a fungus enters, infects and multiplies in the body. Fungi can live in water, soil, air and plants. Fungi affect any part of the body, including the mouth, throat, esophagus, lungs, bladder, genital area and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal. A few common fungal infections are yeast infections that affect the genital area, esophagus and urinary tract caused by Candida. 

Invasive aspergillosis: A fungal infection that starts in the lungs and spreads throughout the bloodstream to other organs.

Esophageal candidiasis: A yeast (a type of fungus) infection that may cause white patching in the mouth and throat. 

Candidemia: A fungal infection in the blood.

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