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  3. VPARIN 25000I.U INJECTION

VPARIN 25000I.U INJECTION, Pack of 1 INJECTION
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

HEPARIN-25000I.U

Manufacturer/Marketer :

Vh Bhagat & Company

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About VPARIN 25000I.U INJECTION

VPARIN 25000I.U INJECTION belongs to a class of drugs called anticoagulants or blood thinners. VPARIN 25000I.U INJECTION is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.  Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. VPARIN 25000I.U INJECTION works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot) preventing blood clot formation.

VPARIN 25000I.U INJECTION will be administered by a healthcare professional; do not self-administer. Some people may experience hemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of VPARIN 25000I.U INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to VPARIN 25000I.U INJECTION or any other medicines, please tell your doctor. It is not known whether VPARIN 25000I.U INJECTION harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using VPARIN 25000I.U INJECTION. VPARIN 25000I.U INJECTION is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking VPARIN 25000I.U INJECTION.

Uses of VPARIN 25000I.U INJECTION

Prevention of blood clots.

Directions for Use

VPARIN 25000I.U INJECTION will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

VPARIN 25000I.U INJECTION is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). VPARIN 25000I.U INJECTION also reduces the risk of blood clots during surgeries (like heart surgery). VPARIN 25000I.U INJECTION is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Storage

Keep VPARIN 25000I.U INJECTION out of the sight and reach of children.

Drug Warnings

Use VPARIN 25000I.U INJECTION cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving VPARIN 25000I.U INJECTION. Patients should inform the doctor that they are receiving VPARIN 25000I.U INJECTION before any surgery is scheduled.

Drug-Drug Interactions

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HeparinAlteplase
Critical
HeparinTenecteplase
Critical

Drug-Drug Interactions

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HeparinAlteplase
Critical
How does the drug interact with Vparin 25000i.u Injection:
Taking Alteplase with Vparin 25000i.u Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Vparin 25000i.u Injection with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinTenecteplase
Critical
How does the drug interact with Vparin 25000i.u Injection:
Taking Tenecteplase with Vparin 25000i.u Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Vparin 25000i.u Injection with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Vparin 25000i.u Injection:
Using Vparin 25000i.u Injection with Oritavancin can make Vparin 25000i.u Injection less effective as a therapy.

How to manage the interaction:
Vparin 25000i.u Injection is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Vparin 25000i.u Injection's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Vparin 25000i.u Injection:
When Vparin 25000i.u Injection is taken with bazedoxifene the effects of Vparin 25000i.u Injection are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Vparin 25000i.u Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinTiclopidine
Critical
How does the drug interact with Vparin 25000i.u Injection:
Taking Ticlopidine with Vparin 25000i.u Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Vparin 25000i.u Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinMifepristone
Critical
How does the drug interact with Vparin 25000i.u Injection:
Taking Mifepristone with Vparin 25000i.u Injection can increase the risk of negative side effects.

How to manage the interaction:
Taking Vparin 25000i.u Injection with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinUrokinase
Severe
How does the drug interact with Vparin 25000i.u Injection:
Taking Vparin 25000i.u Injection with Urokinase can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Vparin 25000i.u Injection with Urokinase can result in an interaction, but it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HeparinSulfadiazine
Severe
How does the drug interact with Vparin 25000i.u Injection:
Sulfadiazine enhances the effects of Vparin 25000i.u Injection by slowing its breakdown.

How to manage the interaction:
Co-administration of Sulfadiazine with Vparin 25000i.u Injection can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
HeparinCefpodoxime
Severe
How does the drug interact with Vparin 25000i.u Injection:
Co-administration of Cefpodoxime with Vparin 25000i.u Injection may enhance the levels or effects of Vparin 25000i.u Injection by anticoagulation (preventing blood from clotting).

How to manage the interaction:
Although there is an interaction, Cefpodoxime can be taken with Vparin 25000i.u Injection if prescribed by the doctor. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
HeparinDicoumarol
Severe
How does the drug interact with Vparin 25000i.u Injection:
Coadministration of Vparin 25000i.u Injection and dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although taking Vparin 25000i.u Injection and Dicoumarol together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-25000I.UHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-25000I.UHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Vparin 25000i.u Injection along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Vparin 25000i.u Injection.

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

VPARIN 25000I.U INJECTION Substitute

Substitutes safety advice

Product Substitutes

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:29 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, you are not recommended to take ibuprofen with VPARIN 25000I.U INJECTION as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with VPARIN 25000I.U INJECTION.

Yes, VPARIN 25000I.U INJECTION may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, VPARIN 25000I.U INJECTION may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, VPARIN 25000I.U INJECTION may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking VPARIN 25000I.U INJECTION to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Drug-Drug Interactions Checker List

  • SALICYLIC ACID
  • IBUPROFEN
  • INDOMETHACIN
  • PHENYLBUTAZONE
  • CELECOXIB
  • HYDROXYCHLOROQUINE
  • ABCIXIMAB
  • DIPYRIDAMOLE
  • DIGITALIS
  • TETRACYCLINE
  • NITROGLYCERIN

Special Advise

Regular blood tests are advised while taking VPARIN 25000I.U INJECTION to monitor prothrombin, platelets and coagulation time on regular basis.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung) is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath. 

Stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours.

Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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