Zabesta AM Tablet 10's belongs to the class of medicines called antihypertensives used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart diseases, irregular heartbeat, and other complications.

Zabesta AM Tablet 10's contains Amlodipine (calcium channel blocker) and Bisoprolol (beta blocker). Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol helps in relaxing our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.

Take Zabesta AM Tablet 10's with or without food as prescribed by your doctor with a full glass of water. You may have common side effects like headache, feeling exhausted and swollen ankles that usually resolve after some time. Prolonged intake of Zabesta AM Tablet 10's may lead to a lowering of blood pressure. So, you must closely monitor your blood pressure if you ever have had a stroke, heart attack, or currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and do not stop taking it suddenly without consulting your doctor.

It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Do not take grapefruit or grapefruit juices with Zabesta AM Tablet 10's as it can increase the concentration of Zabesta AM Tablet 10's and worsen its side effects. Please inform your doctor if you have had an allergic reaction to Zabesta AM Tablet 10's, is pregnant or planning to get pregnant, is breastfeeding, has liver disease, kidney disease, heart failure, diabetes, heart valve problem or heart attack. Reducing the amount of table salt (sodium chloride) in your food often relieves the swelling of the body. Zabesta AM Tablet 10's is prescribed to adults and children more than six years of age.

Zabesta AM Tablet 10's is a combination of two medicines namely: Amlodipine and Bisoprolol, which together helps in lowering raised blood pressure effectively. Amlodipine, a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol (beta blocker) helps in relaxing our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.

• Bradycardia (slow heart rate)
• Increased blood potassium level
• Cold extremities
• Gastrointestinal disturbances including nausea
• Fatigue

Don't stop taking Zabesta AM Tablet 10's without talking to your doctor first. Stopping Zabesta AM Tablet 10's abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use Zabesta AM Tablet 10's if you have very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. It should not be given to the children less than 12 years of age. Before taking Zabesta AM Tablet 10's you should tell doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood sugar level (hypoglycaemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome).

Drug-Drug Interaction: Zabesta AM Tablet 10's may interact with other beta-blockers (acebutolol, atenolol, bisoprolol, carteolol, esmolol, metoprolol, nadolol, nebivolol or sotalol) causing a dangerous drop in the heart rate. It also reacts with other anti-hypertensive drugs (aliskiren, amiloride, enalapril, captopril, quinapril, diltiazem). Besides this, Zabesta AM Tablet 10's should not be used with other asthma medications (theophylline, aminophylline), potassium-rich supplements or any other pain killers (ibuprofen). If you are using these medicines, tell your doctor before taking Zabesta AM Tablet 10's. 

Drug-Food Interaction: Zabesta AM Tablet 10's is known to interact with grapefruit and protein-enriched foods. Using Zabesta AM Tablet 10's together with ayurvedic, homoeopathy, Unani, herbal supplements, or any other OTC items may decrease the effects of Zabesta AM Tablet 10's. Hence, it is better to maintain at least 2 hours gap between the administration of Zabesta AM Tablet 10's and these products. 

Drug-Disease Interaction: Zabesta AM Tablet 10's should not be given to the people with diabetes, thyroid disease, asthma, cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease or heart failure.

• ACEBUTOLOL
• ATENOLOL
• BISOPROLOL
• CARTEOLOL
• ESMOLOL
• METOPROLOL
• NADOLOL
• NEBIVOLOL
• SOTALOL
• ALISKIREN
• AMILORIDE
• ENALAPRIL
• CAPTOPRIL
• QUINAPRIL
• DILTIAZEM
• THEOPHYLLINE
• AMINOPHYLLINE
• IBUPROFEN

• Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
• Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
• Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
• If you are taking alcohol then only one serving for women and two servings for men is advisable.
• Quitting smoking is the best strategy to lower the risk of heart disease.
• Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
• Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.
• Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.

Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.