Amlodipine+bisoprolol
About
Amlodipine+bisoprolol belongs to the class of medicines called antihypertensives used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart diseases, irregular heartbeat, and other complications.
Amlodipine+bisoprolol contains Amlodipine (calcium channel blocker) and Bisoprolol (beta blocker). Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol helps in relaxing our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.
Take Amlodipine+bisoprolol with or without food as prescribed by your doctor with a full glass of water. You may have common side effects like headache, feeling exhausted and swollen ankles that usually resolve after some time. Prolonged intake of Amlodipine+bisoprolol may lead to a lowering of blood pressure. So, you must closely monitor your blood pressure if you ever have had a stroke, heart attack, or currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and do not stop taking it suddenly without consulting your doctor.
It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Do not take grapefruit or grapefruit juices with Amlodipine+bisoprolol as it can increase the concentration of Amlodipine+bisoprolol and worsen its side effects. Please inform your doctor if you have had an allergic reaction to Amlodipine+bisoprolol, is pregnant or planning to get pregnant, is breastfeeding, has liver disease, kidney disease, heart failure, diabetes, heart valve problem or heart attack. Reducing the amount of table salt (sodium chloride) in your food often relieves the swelling of the body. Amlodipine+bisoprolol is prescribed to adults and children more than six years of age.
Uses of Amlodipine+bisoprolol
Medicinal Benefits
Amlodipine+bisoprolol is a combination of two medicines namely: Amlodipine and Bisoprolol, which together helps in lowering raised blood pressure effectively. Amlodipine, a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol (beta blocker) helps in relaxing our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.
Directions for Use
Storage
Side Effects of Amlodipine+bisoprolol
- Bradycardia (slow heart rate)
- Increased blood potassium level
- Cold extremities
- Gastrointestinal disturbances including nausea
- Fatigue
In-Depth Precautions and Warning
Drug Warnings
Don't stop taking Amlodipine+bisoprolol without talking to your doctor first. Stopping Amlodipine+bisoprolol abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use Amlodipine+bisoprolol if you have very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. It should not be given to the children less than 12 years of age. Before taking Amlodipine+bisoprolol you should tell doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood sugar level (hypoglycaemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome).
Drug Interactions
Drug-Drug Interaction: Amlodipine+bisoprolol may interact with other beta-blockers (acebutolol, atenolol, bisoprolol, carteolol, esmolol, metoprolol, nadolol, nebivolol or sotalol) causing a dangerous drop in the heart rate. It also reacts with other anti-hypertensive drugs (aliskiren, amiloride, enalapril, captopril, quinapril, diltiazem). Besides this, Amlodipine+bisoprolol should not be used with other asthma medications (theophylline, aminophylline), potassium-rich supplements or any other pain killers (ibuprofen). If you are using these medicines, tell your doctor before taking Amlodipine+bisoprolol.
Drug-Food Interaction: Amlodipine+bisoprolol is known to interact with grapefruit and protein-enriched foods. Using Amlodipine+bisoprolol together with ayurvedic, homoeopathy, Unani, herbal supplements, or any other OTC items may decrease the effects of Amlodipine+bisoprolol. Hence, it is better to maintain at least 2 hours gap between the administration of Amlodipine+bisoprolol and these products.
Drug-Disease Interaction: Amlodipine+bisoprolol should not be given to the people with diabetes, thyroid disease, asthma, cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease or heart failure.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Amlodipine+bisoprolol to avoid unpleasant side-effects.
Pregnancy
unsafeAmlodipine+bisoprolol should not be taken until prescribed. Amlodipine+bisoprolol can have some harmful effects on the baby (foetus), Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast Feeding
cautionAmlodipine+bisoprolol is usually not recommended in breastfeeding mothers. Limited human data available suggests that the drug does not do any significant harm to the baby. Consume only if benefits outweigh risks.
Driving
unsafeIt is not recommended to drive after taking Amlodipine+bisoprolol as it may occasionally cause drowsiness or fatigue.
Liver
cautionAmlodipine+bisoprolol to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionAmlodipine+bisoprolol to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
unsafeAmlodipine+bisoprolol is not recommended in children. The safety and efficacy of Amlodipine+bisoprolol in children have not yet been established.
Habit Forming
Diet & Lifestyle Advise
- Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
- Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
- Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
- If you are taking alcohol then only one serving for women and two servings for men is advisable.
- Quitting smoking is the best strategy to lower the risk of heart disease.
- Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
- Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.
- Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.
Special Advise
Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
Patients Concern
Disease/Condition Glossary
Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.
FAQs
It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shot up any time. If you have any discomfort, please consult your doctor immediately
Usually, Amlodipine+bisoprolol is prescribed for a long term or life long treatment for heart-related chronic conditions and disorders. You should follow the doctor's advise and take it until your doctor tells to stop. Suddenly stop taking Amlodipine+bisoprolol may raise your blood pressure and increase your risk of heart att
Your doctor may probably tell you to stop taking Amlodipine+bisoprolol as it lowers blood pressure (hypotension) when combined with general anaesthesia before surgery. So, please inform your doctor before surgery if you are taking Amlodipine+bisoprolol.
In case, you have missed a dose of Amlodipine+bisoprolol, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both the doses together. Take only one dose, taking a double dose of Amlodipine+bisoprolol will lead to low blood pressure.
Yes, Amlodipine+bisoprolol is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
Yes, Amlodipine+bisoprolol can cause dry mouth. Therefore, it is always advised to increase fluid intake while taking Amlodipine+bisoprolol. If you still feel excessive thirsty, please consult your doctor and do as advised for best results of Amlodipine+bisoprolol.
