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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Aug 20, 2024 | 1:17 PM IST

About ZAVEDOS INJECTION 5MG

ZAVEDOS INJECTION 5MG is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. ZAVEDOS INJECTION 5MG is used in the treatment of Acute Myeloid Leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

ZAVEDOS INJECTION 5MG contains Idarubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis. Thus, ZAVEDOS INJECTION 5MG stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death. ZAVEDOS INJECTION 5MG is used in combination with other medicines for the treatment of acute myeloid leukemia.

ZAVEDOS INJECTION 5MG may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, stomach pain, headache, pale skin, difficulty urinating, fever, and pain at the site of injection. Most of these side effects of ZAVEDOS INJECTION 5MG do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. ZAVEDOS INJECTION 5MG is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

ZAVEDOS INJECTION 5MG should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with ZAVEDOS INJECTION 5MG. ZAVEDOS INJECTION 5MG is contraindicated for pregnant women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease, bone marrow suppression, or heart disease, as it may cause serious adverse effects or worsen the condition. Avoid alcohol consumption with ZAVEDOS INJECTION 5MG as it may increase the risk of liver damage. This medicine is not recommended for children as safety and efficacy are not established.

Uses of ZAVEDOS INJECTION 5MG

Acute Myeloid Leukemia.

Medicinal Benefits

ZAVEDOS INJECTION 5MG contains Idarubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis. Thus, ZAVEDOS INJECTION 5MG stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Directions for Use

Your doctor will administer ZAVEDOS INJECTION 5MG. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ZAVEDOS INJECTION 5MG

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Dizziness
  • Weakness
  • Fever
  • Pale skin
  • Headache
  • Difficulty urinating
  • Injection site reactions
  • Pain at the site of injection

Drug Warnings

ZAVEDOS INJECTION 5MG should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with ZAVEDOS INJECTION 5MG. ZAVEDOS INJECTION 5MG is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease, pre-existing bone marrow suppression, or pre-existing heart disease, as it may cause serious adverse effects or worsen the condition. Avoid alcohol consumption with ZAVEDOS INJECTION 5MG as it may increase the risk of liver damage. This medicine is not recommended for children as safety and efficacy are not established.

Drug Interactions

Drug-Drug Interactions: No interactions found.

Drug-Food Interactions: ZAVEDOS INJECTION 5MG may interact with alcohol. Therefore, avoid alcohol consumption with ZAVEDOS INJECTION 5MG as it may increase the risk of liver damage.

Drug-Disease Interactions: Inform your doctor if you have liver or kidney disease before starting treatment with ZAVEDOS INJECTION 5MG.

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking ZAVEDOS INJECTION 5MG as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Special Advise

  • ZAVEDOS INJECTION 5MG is intended for intravenous administration only. 
  • This medicine should be administered only by a well-trained and experienced oncologist in a hospital setting.
  • Regular blood tests are recommended while receiving ZAVEDOS INJECTION 5MG to monitor the number and type of cells in the blood, liver and kidney functioning.
  • Cardiac function should be monitored carefully. Regular ECG should be done to check for any changes.

Disease/Condition Glossary

Acute Myeloid Leukemia (AML): It is a type of cancer that occurs in the bone marrow and blood. It abnormally increases the number of immature white blood cells. The symptoms include unexplained weight loss, excessive sweating, bone pain, frequent nosebleeds, heavier-than-normal periods in females, and shortness of breath. The risk factors include smoking and genetic or blood disorders.

About ZAVEDOS INJECTION 5MG

ZAVEDOS INJECTION 5MG is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. ZAVEDOS INJECTION 5MG is used in the treatment of Acute Myeloid Leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

ZAVEDOS INJECTION 5MG contains Idarubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis. Thus, ZAVEDOS INJECTION 5MG stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death. ZAVEDOS INJECTION 5MG is used in combination with other medicines for the treatment of acute myeloid leukemia.

ZAVEDOS INJECTION 5MG may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, stomach pain, headache, pale skin, difficulty urinating, fever, and pain at the site of injection. Most of these side effects of ZAVEDOS INJECTION 5MG do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. ZAVEDOS INJECTION 5MG is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

ZAVEDOS INJECTION 5MG should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with ZAVEDOS INJECTION 5MG. ZAVEDOS INJECTION 5MG is contraindicated for pregnant women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease, bone marrow suppression, or heart disease, as it may cause serious adverse effects or worsen the condition. Avoid alcohol consumption with ZAVEDOS INJECTION 5MG as it may increase the risk of liver damage. This medicine is not recommended for children as safety and efficacy are not established.

Non returnable*
COD available

Online payment accepted

Prescription drug

Whats That

tooltip
Non returnable*
COD available

Online payment accepted

Composition

IDARUBICIN-5MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of ZAVEDOS INJECTION 5MG

Acute Myeloid Leukemia.

Medicinal Benefits

ZAVEDOS INJECTION 5MG contains Idarubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis. Thus, ZAVEDOS INJECTION 5MG stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Side Effects of ZAVEDOS INJECTION 5MG

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Dizziness
  • Weakness
  • Fever
  • Pale skin
  • Headache
  • Difficulty urinating
  • Injection site reactions
  • Pain at the site of injection

Directions for Use

Your doctor will administer ZAVEDOS INJECTION 5MG. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

ZAVEDOS INJECTION 5MG should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with ZAVEDOS INJECTION 5MG. ZAVEDOS INJECTION 5MG is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease, pre-existing bone marrow suppression, or pre-existing heart disease, as it may cause serious adverse effects or worsen the condition. Avoid alcohol consumption with ZAVEDOS INJECTION 5MG as it may increase the risk of liver damage. This medicine is not recommended for children as safety and efficacy are not established.

Therapeutic Class

ANTINEOPLASTIC

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking ZAVEDOS INJECTION 5MG as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Habit Forming

No

Special Advise

  • ZAVEDOS INJECTION 5MG is intended for intravenous administration only. 
  • This medicine should be administered only by a well-trained and experienced oncologist in a hospital setting.
  • Regular blood tests are recommended while receiving ZAVEDOS INJECTION 5MG to monitor the number and type of cells in the blood, liver and kidney functioning.
  • Cardiac function should be monitored carefully. Regular ECG should be done to check for any changes.

Disease/Condition Glossary

Acute Myeloid Leukemia (AML): It is a type of cancer that occurs in the bone marrow and blood. It abnormally increases the number of immature white blood cells. The symptoms include unexplained weight loss, excessive sweating, bone pain, frequent nosebleeds, heavier-than-normal periods in females, and shortness of breath. The risk factors include smoking and genetic or blood disorders.