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ZAVEDOS INJECTION 5MG

ZAVEDOS INJECTION 5MG

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Prescription drug
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Composition

IDARUBICIN-5MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About ZAVEDOS INJECTION 5MG

ZAVEDOS INJECTION 5MG is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. ZAVEDOS INJECTION 5MG is used in the treatment of Acute Myeloid Leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

ZAVEDOS INJECTION 5MG contains Idarubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis. Thus, ZAVEDOS INJECTION 5MG stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death. ZAVEDOS INJECTION 5MG is used in combination with other medicines for the treatment of acute myeloid leukemia.

ZAVEDOS INJECTION 5MG may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, stomach pain, headache, pale skin, difficulty urinating, fever, and pain at the site of injection. Most of these side effects of ZAVEDOS INJECTION 5MG do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. ZAVEDOS INJECTION 5MG is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

ZAVEDOS INJECTION 5MG should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with ZAVEDOS INJECTION 5MG. ZAVEDOS INJECTION 5MG is contraindicated for pregnant women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease, bone marrow suppression, or heart disease, as it may cause serious adverse effects or worsen the condition. Avoid alcohol consumption with ZAVEDOS INJECTION 5MG as it may increase the risk of liver damage. This medicine is not recommended for children as safety and efficacy are not established.

Uses of ZAVEDOS INJECTION 5MG

Acute Myeloid Leukemia.

Medicinal Benefits

ZAVEDOS INJECTION 5MG contains Idarubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis. Thus, ZAVEDOS INJECTION 5MG stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Directions for Use

Your doctor will administer ZAVEDOS INJECTION 5MG. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ZAVEDOS INJECTION 5MG

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Dizziness
  • Weakness
  • Fever
  • Pale skin
  • Headache
  • Difficulty urinating
  • Injection site reactions
  • Pain at the site of injection

Drug Warnings

ZAVEDOS INJECTION 5MG should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with ZAVEDOS INJECTION 5MG. ZAVEDOS INJECTION 5MG is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease, pre-existing bone marrow suppression, or pre-existing heart disease, as it may cause serious adverse effects or worsen the condition. Avoid alcohol consumption with ZAVEDOS INJECTION 5MG as it may increase the risk of liver damage. This medicine is not recommended for children as safety and efficacy are not established.

Drug Interactions

Drug-Drug Interactions: No interactions found.

Drug-Food Interactions: ZAVEDOS INJECTION 5MG may interact with alcohol. Therefore, avoid alcohol consumption with ZAVEDOS INJECTION 5MG as it may increase the risk of liver damage.

Drug-Disease Interactions: Inform your doctor if you have liver or kidney disease before starting treatment with ZAVEDOS INJECTION 5MG.

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking ZAVEDOS INJECTION 5MG as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Special Advise

  • ZAVEDOS INJECTION 5MG is intended for intravenous administration only. 
  • This medicine should be administered only by a well-trained and experienced oncologist in a hospital setting.
  • Regular blood tests are recommended while receiving ZAVEDOS INJECTION 5MG to monitor the number and type of cells in the blood, liver and kidney functioning.
  • Cardiac function should be monitored carefully. Regular ECG should be done to check for any changes.

Disease/Condition Glossary

Acute Myeloid Leukemia (AML): It is a type of cancer that occurs in the bone marrow and blood. It abnormally increases the number of immature white blood cells. The symptoms include unexplained weight loss, excessive sweating, bone pain, frequent nosebleeds, heavier-than-normal periods in females, and shortness of breath. The risk factors include smoking and genetic or blood disorders.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Other Info - ZAV0003

FAQs

ZAVEDOS INJECTION 5MG contains Idarubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis.
If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with ZAVEDOS INJECTION 5MG as it may cause infections.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol with ZAVEDOS INJECTION 5MG as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. If you are pregnant or planning pregnancy, inform your doctor before receiving ZAVEDOS INJECTION 5MG. Use effective contraception to avoid pregnancy while on treatment with this medicine.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Because of the possibility of major adverse events in nursing infants from the medicine, women should quit nursing prior to taking the drug and refrain from breastfeeding during treatment and for 14 days after the final dosage.

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Driving

Unsafe

ZAVEDOS INJECTION 5MG causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after taking ZAVEDOS INJECTION 5MG.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving ZAVEDOS INJECTION 5MG. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Your doctor may also suggest liver function tests while on treatment with ZAVEDOS INJECTION 5MG.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving ZAVEDOS INJECTION 5MG. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Your doctor may also suggest renal function tests while on treatment with ZAVEDOS INJECTION 5MG.

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Children

Unsafe

ZAVEDOS INJECTION 5MG is not recommended for use in children as the safety and efficacy have not been established.

Author Details

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