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Whats That
About Zaxaglit 5mg Tablet
Zaxaglit 5mg Tablet contains saxagliptin which belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors used in the treatment of type 2 diabetes in adults. Zaxaglit 5mg Tablet is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It is the first-line therapy for patients with type 2 diabetes that restores the body's response to insulin. Insulin is the hormone that controls sugar levels in your blood. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.
Zaxaglit 5mg Tablet work by blocking the action of DPP-4 (an enzyme which destroys hormone ‘Incretin’). The enzyme ‘Incretins’ help to produce more insulin only when required and reduce blood sugar level produced by the liver when not needed. Zaxaglit 5mg Tablet should not be used in patients with type 1 diabetes and for the treatment of diabetic ketoacidosis.
Zaxaglit 5mg Tablet should be taken with food or empty stomach. However, it should be taken at the same time of the day each time for best results. For better advice, your doctor will decide, what dose should be taken and it can change timely depending upon your condition. The most common side effect of Zaxaglit 5mg Tablet are hypoglycemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold) and headache.
Prolonged intake of Zaxaglit 5mg Tablet may cause acute pancreatitis (swollen pancreas), and critical kidney problem. Increased risk of hypoglycemia (low blood sugar level) can occur when Zaxaglit 5mg Tablet is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Zaxaglit 5mg Tablet. Severe allergic reactions might occur in some patients taking Zaxaglit 5mg Tablet like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions including Stevens-Johnson syndrome. Safety and efficacy of Zaxaglit 5mg Tablet in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Zaxaglit 5mg Tablet should be closely monitored as severe drug interaction has been observed.
Uses of Zaxaglit 5mg Tablet
Directions for Use
Medicinal Benefits
Zaxaglit 5mg Tablet work by blocking the action of DPP-4 (an enzyme which destroys hormone ‘Incretin’). The enzyme ‘Incretins’ help to produce more insulin only when required and reduce blood sugar level produced by the liver when not needed. Thus, Zaxaglit 5mg Tablet plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.
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Drug Warnings
Increased risk of hypoglycemia (low blood sugar level) can occur when Zaxaglit 5mg Tablet is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Zaxaglit 5mg Tablet. Prolonged intake of Zaxaglit 5mg Tablet may cause acute pancreatitis (swollen pancreas), and critical kidney problem. Severe allergic reactions might occur in some patients taking Zaxaglit 5mg Tablet like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions including Stevens-Johnson syndrome. Safety and efficacy of Zaxaglit 5mg Tablet in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Zaxaglit 5mg Tablet should be closely monitored as severe drug interaction has been observed.
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Yes, Zaxaglit 5mg Tablet is known to cause stomach upset, indigestion, nausea, and diarrhea. To avoid these side effects please take Zaxaglit 5mg Tablet with a meal. Also, Zaxaglit 5mg Tablet should be taken at evenly spaced intervals to avoid any unpleasant side effects and for best results.
Not recommended in patients with high levels of blood cholesterol as Zaxaglit 5mg Tablet has been reported to increase blood cholesterol levels in a normal patient and thus not recommended in patients with hyperlipidemia.
The patient is advised to take the missed dose as soon as possible, otherwise, jump to next dose. A patient should never take a double dose to compensate for the missed dose. It may aggravate harmful side effects.
According to American Diabetes Association, most of the studies carried out on Zaxaglit 5mg Tablet and its ability to cause cancer resulted in a conclusion that Zaxaglit 5mg Tablet is not associated with any form of cancer& hence is safe to use in patients.
A patient if accidentally takes an overdose of Zaxaglit 5mg Tablet may experience collapse, seizure attack, troubled breathing. In such a case without any delay, emergency health services must be contacted and medical help should be sought.
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Disease/Condition Glossary
Type 2 diabetes is a condition where the body is unable to make sufficient insulin, or the insulin that it makes doesn't work properly or utilized by our body. This can cause high blood sugar levels (hyperglycemia). Symptoms of type 2 diabetes include increased thirst, frequent urination, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), and retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and increase the chance of heart attack or stroke.
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