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  3. ZEPTOL 400MG TABLET

ZEPTOL 400MG TABLET, Pack of 10 TABLETS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Composition :

CARBAMAZEPINE-400MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About ZEPTOL 400MG TABLET

ZEPTOL 400MG TABLET belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy (fits) and trigeminal neuralgia (pain in the face's nerves). Epilepsy is a neurological disorder in which there is a sudden rush of electric impulses (electric activity) in the brain. As a result, the brain's electrical rhythms become imbalanced, resulting in recurrent episodes of seizures or fits. Trigeminal neuralgia is a condition which affects the trigeminal nerve that carries sensations from the face to the brain. 

ZEPTOL 400MG TABLET contains 'Carbamazepine' that reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, ZEPTOL 400MG TABLET decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. 

You are advised to take ZEPTOL 400MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, tiredness, uncontrolled movements, nausea, headache, changes in liver enzymes or low white blood cells count, and minor skin reactions. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking ZEPTOL 400MG TABLET for as long as your doctor has prescribed. Please do not stop taking ZEPTOL 400MG TABLET without consulting your doctor to avoid worsening of seizures. Do not take ZEPTOL 400MG TABLET if you are pregnant or planning for pregnancy unless prescribed by the doctor as it could lead to serious congenital disabilities. It is safe to take ZEPTOL 400MG TABLET while breastfeeding; however, consult your doctor immediately if you think that the baby is having side-effects like excessive sleepiness, skin reactions or yellowing of skin or eyes. ZEPTOL 400MG TABLET causes drowsiness and dizziness, so drive only if you are alert. ZEPTOL 400MG TABLET should not be given to children unless prescribed. Avoid consuming alcohol along with ZEPTOL 400MG TABLET as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of ZEPTOL 400MG TABLET

Epilepsy/seizures, Trigeminal neuralgia

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

ZEPTOL 400MG TABLET belongs to a group of medicines called anti-convulsants or anti-epileptics used to treat epilepsy and trigeminal neuralgia (face nerve pain). ZEPTOL 400MG TABLET works by reducing the electrical impulses and subsequent firing of the nerve impulses that cause fits. ZEPTOL 400MG TABLET decreases the excessive and abnormal nerve activity in the brain, thereby helping in controlling seizures. ZEPTOL 400MG TABLET is also used to relieve nerve pain associated with trigeminal neuralgia. People with glossopharyngeal neuralgia may also experience benefit with ZEPTOL 400MG TABLET. ZEPTOL 400MG TABLET is not associated with any psychological or physical dependence, and there is no potential for abuse.

Storage

Keep ZEPTOL 400MG TABLET out of reach and sight of children.
Side effects of Zeptol 400mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Do not take ZEPTOL 400MG TABLET if you are allergic to 'Carbamezapine' or any of its contents, have serious heart problems, blood illnesses, bone marrow problems, hypothyroidism, glaucoma, urinary retention, osteoporosis or taking anti-depressants called monoamine oxidase inhibitors (MAO's) within the last 14 days or taking herbal preparations containing St. John's wort as an antidepressant. Inform the doctor if you have low sodium levels in the blood or take medicines that could lower the blood's sodium levels, or using hormonal contraceptives. Do not stop taking ZEPTOL 400MG TABLET without consulting your doctor to avoid worsening of seizures episodes. Do not take ZEPTOL 400MG TABLET if you are pregnant unless prescribed by the doctor as ZEPTOL 400MG TABLET might cause serious congenital disabilities. It is safe to take ZEPTOL 400MG TABLET while breastfeeding; however, consult your doctor immediately if you think that the baby is having side-effects like excessive sleepiness, skin reactions or yellowing of skin or eyes. ZEPTOL 400MG TABLET causes drowsiness and dizziness, so drive only if you are alert. ZEPTOL 400MG TABLET should not be given to people less than 18 years of age until and unless prescribed by the doctor. Avoid consuming alcohol along with ZEPTOL 400MG TABLET as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies or mood swings. 

Drug-Drug Interactions

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CarbamazepineNifedipine
Critical
CarbamazepineNimodipine
Critical

Drug-Drug Interactions

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CarbamazepineNifedipine
Critical
How does the drug interact with Zeptol 400mg Tablet:
Coadministration of Nifedipine with Zeptol 400mg Tablet can reduce the blood levels of nifedipine, which may make the medication less effective.

How to manage the interaction:
Taking Nifedipine with Zeptol 400mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
CarbamazepineNimodipine
Critical
How does the drug interact with Zeptol 400mg Tablet:
When Nimodipine is taken with Zeptol 400mg Tablet, it may decrease the blood levels of Nimodipine, which may make Nimodipine less effective in treating your condition.

How to manage the interaction:
Taking Nimodipine with Zeptol 400mg Tablet is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
CarbamazepineIsocarboxazid
Critical
How does the drug interact with Zeptol 400mg Tablet:
Taking Zeptol 400mg Tablet with Isocarboxazid can cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Using Zeptol 400mg Tablet with Isocarboxazid is not recommended, it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
CarbamazepinePraziquantel
Critical
How does the drug interact with Zeptol 400mg Tablet:
When Praziquantel is taken with Zeptol 400mg Tablet, it may decrease the blood levels of Praziquantel, which may make Praziquantel less effective in treating your condition.

How to manage the interaction:
Taking Zeptol 400mg Tablet with Praziquantel is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
CarbamazepineMoclobemide
Critical
How does the drug interact with Zeptol 400mg Tablet:
Taking Zeptol 400mg Tablet with Moclobemide can increase the risk and severity of side effects.

How to manage the interaction:
Using Zeptol 400mg Tablet with Moclobemide is not recommended, it can be taken if recommended by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
CarbamazepineArtemether
Critical
How does the drug interact with Zeptol 400mg Tablet:
Using Zeptol 400mg Tablet with Artemether may decrease the blood levels of Artemether, which may make Artemether less effective in treating your malaria.

How to manage the interaction:
Taking Zeptol 400mg Tablet with Artemether is not recommended, but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.
CarbamazepineLinezolid
Critical
How does the drug interact with Zeptol 400mg Tablet:
Using Zeptol 400mg Tablet with Linezolid can cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Zeptol 400mg Tablet and Linezolid together is not recommended, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
CarbamazepineSelegiline
Critical
How does the drug interact with Zeptol 400mg Tablet:
Taking Zeptol 400mg Tablet with Selegiline can cause serotonin syndrome. (Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selegiline with Zeptol 400mg Tablet is not recommended, but it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
CarbamazepineRanolazine
Critical
How does the drug interact with Zeptol 400mg Tablet:
Taking ranolazine with Zeptol 400mg Tablet may significantly reduce the blood levels of ranolazine, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Ranolazine with Zeptol 400mg Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
CarbamazepinePirfenidone
Critical
How does the drug interact with Zeptol 400mg Tablet:
Taking Pirfenidone with Zeptol 400mg Tablet it reduces the levels and effects of Pirfenidone.

How to manage the interaction:
Taking Pirfenidone with Zeptol 400mg Tablet is not recommended but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

ZEPTOL 400MG TABLET Substitute

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:30 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

ZEPTOL 400MG TABLET decreases the brain's excessive and abnormal nerve activity by blocking sodium currents in your brain and body. This reduces abnormal electrical activity between your nerve cells.

Do not discontinue ZEPTOL 400MG TABLET without consulting your doctor. To treat your condition effectually continue taking ZEPTOL 400MG TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking ZEPTOL 400MG TABLET; your doctor will reduce the dose gradually to avoid worsening of seizures.

ZEPTOL 400MG TABLET may affect the way hormone contraceptives work in your body. This may cause spotting or breakthrough bleeding. ZEPTOL 400MG TABLET may increase the risk of pregnancy as it makes the contraceptive less effective. Talk to your doctor, he/she will discuss the most suitable type of contraception while taking ZEPTOL 400MG TABLET to avoid pregnancy.

ZEPTOL 400MG TABLET may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective contraception method during the treatment with ZEPTOL 400MG TABLET and 2 weeks after the last dose. Avoid getting pregnant while taking ZEPTOL 400MG TABLET as it could lead to serious congenital disabilities. Do not stop taking ZEPTOL 400MG TABLET without consulting your doctor.

ZEPTOL 400MG TABLET may cause hyponatremia (low sodium levels in the blood). This could lead to confusion, reduced concentration, vision problems, nausea, vomiting or worsening of seizures. Regular monitoring of sodium levels is advised while taking ZEPTOL 400MG TABLET. Consult your doctor if you experience these symptoms.

Dry mouth could be a side-effect of ZEPTOL 400MG TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • QUETIAPINE
  • ALPRAZOLAM
  • AMITRIPTYLINE
  • DULOXETINE
  • SERTRALINE
  • FLUOXETINE
  • ERYTHROMYCIN
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  • GABAPENTIN
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  • PREGABALIN
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  • LEVOTHYROXINE SODIUM
  • LITHIUM
  • MELATONIN
  • WARFARIN
  • DIPHENHYDRAMINE
  • CHOLECALCIFEROL

Special Advise

  • Regular monitoring of sodium levels while taking ZEPTOL 400MG TABLET is advised to prevent hyponatremia.
  • Prolonged intake of ZEPTOL 400MG TABLET can cause severe skin reactions called Stevens Johnsons syndrome (SJS) and toxic epidermal necrolysis (TEN). So in case you have any skin blister or rash immediately contact a doctor. 
  • ZEPTOL 400MG TABLET may cause low blood cell count, so if you have any red or purple spots on the body, let your doctor know about this. 

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterised by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Trigeminal neuralgia: It is a condition affecting the trigeminal nerve in the face that causes painful sensations similar to electric shock on one side of the face. Symptoms include mild to severe facial pain often triggered by speaking, chewing, or brushing the teeth.

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