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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer

Rapross Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Zinase-D 50 mg/10 mg Tablet 15's

Zinase-D 50 mg/10 mg Tablet 15's belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of diclofenac and serratiopeptidase. Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage of the tooth nerve, infection, decay, extraction, or injury.

Zinase-D 50 mg/10 mg Tablet 15's is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Serratiopeptidase is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

You can take Zinase-D 50 mg/10 mg Tablet 15's with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take Zinase-D 50 mg/10 mg Tablet 15's based on your medical condition. Zinase-D 50 mg/10 mg Tablet 15's may have common side effects like stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Most of these side effects of Zinase-D 50 mg/10 mg Tablet 15's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take Zinase-D 50 mg/10 mg Tablet 15's if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. Zinase-D 50 mg/10 mg Tablet 15's may be associated with a small increased risk of heart attack ‘myocardial infarction. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Zinase-D 50 mg/10 mg Tablet 15's

Post-traumatic pain, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Zinase-D 50 mg/10 mg Tablet 15's plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers which cause pain and fever. Zinase-D 50 mg/10 mg Tablet 15's relieves pain and inflammation in arthritic conditions with the benefit of increased antibiotic penetration and micro-circulation at the injury site. Serratiopeptidase present in Zinase-D 50 mg/10 mg Tablet 15's is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zinase-D 50 mg/10 mg Tablet 15's

  • Stomach ache
  • Diarrhoea
  • Nausea (feeling sick)
  • Indigestion

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Zinase-D 50 mg/10 mg Tablet 15's as it may lead to an increase in the risk of liver damage. Patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, and hypertension (high blood pressure), should not take Zinase-D 50 mg/10 mg Tablet 15's. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to pain killers and, complications like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Zinase-D 50 mg/10 mg Tablet 15's. Do not drive or operate heavy machinery as intake of Zinase-D 50 mg/10 mg Tablet 15's may cause dizziness. Patients who had recently undergone heart bypass surgery should take Zinase-D 50 mg/10 mg Tablet 15's with caution and only under medical supervision. Use of Zinase-D 50 mg/10 mg Tablet 15's is contraindicated in kidney failure patients or who are undergoing dialysis.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacOmacetaxine mepesuccinate
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Zinase-D 50 mg/10 mg Tablet:
Co-administration of Zinase-D 50 mg/10 mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Zinase-D 50 mg/10 mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacOmacetaxine mepesuccinate
Severe
How does the drug interact with Zinase-D 50 mg/10 mg Tablet:
Taking Zinase-D 50 mg/10 mg Tablet with Omacetaxine mepesuccinate can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Zinase-D 50 mg/10 mg Tablet and Omacetaxine mepesuccinate but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacRamucirumab
Severe
How does the drug interact with Zinase-D 50 mg/10 mg Tablet:
Co-administration of Zinase-D 50 mg/10 mg Tablet and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of Zinase-D 50 mg/10 mg Tablet and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacEnoxaparin
Severe
How does the drug interact with Zinase-D 50 mg/10 mg Tablet:
Taking Zinase-D 50 mg/10 mg Tablet with Enoxaparin can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Zinase-D 50 mg/10 mg Tablet and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
DiclofenacCidofovir
Severe
How does the drug interact with Zinase-D 50 mg/10 mg Tablet:
Coadministration of Zinase-D 50 mg/10 mg Tablet with cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Zinase-D 50 mg/10 mg Tablet and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
DiclofenacSulindac
Severe
How does the drug interact with Zinase-D 50 mg/10 mg Tablet:
Co-administration of Zinase-D 50 mg/10 mg Tablet and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Zinase-D 50 mg/10 mg Tablet and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacTenofovir disoproxil
Severe
How does the drug interact with Zinase-D 50 mg/10 mg Tablet:
Co-administration of Zinase-D 50 mg/10 mg Tablet with tenofovir disoproxil may increase the risk of developing kidney problems.

How to manage the interaction:
There may be a possible interaction between Zinase-D 50 mg/10 mg Tablet and Tenofovir disoproxil but they can be taken together if your doctor has prescribed them. However consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacTacrolimus
Severe
How does the drug interact with Zinase-D 50 mg/10 mg Tablet:
Co-administration of Zinase-D 50 mg/10 mg Tablet with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Zinase-D 50 mg/10 mg Tablet and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
DiclofenacIbuprofen
Severe
How does the drug interact with Zinase-D 50 mg/10 mg Tablet:
Taking Zinase-D 50 mg/10 mg Tablet and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Zinase-D 50 mg/10 mg Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacCelecoxib
Severe
How does the drug interact with Zinase-D 50 mg/10 mg Tablet:
Co-administration of Zinase-D 50 mg/10 mg Tablet with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Zinase-D 50 mg/10 mg Tablet and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead you can do stretching, low impact aerobic exercise like walking on treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit little as possible, and only for short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a foot rest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS

Zinase-D 50 mg/10 mg Tablet 15's Substitute

Substitutes safety advice
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    17.01per tablet
  • Tolpa D Tablet 10's

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  • Zinase-D 50 mg/10 mg Tablet 10's

    by AYUR

    14.13per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zinase-D 50 mg/10 mg Tablet 15's when taken by patients who are allergic to pain-killers can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease, stomach ulcers and high blood pressure.

You should only take Zinase-D 50 mg/10 mg Tablet 15's if doctor has prescribed you. The maximum recommended dose of Zinase-D 50 mg/10 mg Tablet 15's is twice daily. Zinase-D 50 mg/10 mg Tablet 15's can be one in the morning and one in the evening.

Rheutamoid arthritis is an autoimmune disease that causes chronic inflammation and pain of the joints.

Ankylosing spondylitis is a arthritis of the spine which can lead to the fusion of the vertebrae, lead to pain and inflammation in the spine.

Yes, Zinase-D 50 mg/10 mg Tablet 15's can cause stomach upset. So, it should be preferably taken with food to avoid it.

Drug-Drug Interactions Checker List

  • NIMESULIDE
  • OXYPHENBUTAZONE
  • METAMIZOLE
  • METHOTREXATE
  • WARFARIN

Disease/Condition Glossary

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains, or trauma or post-surgery may require a prolonged amount of time to heal. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation are caused due to sprains, strains, trauma or post-surgery. These types of injuries may require a prolonged amount of time to heal.

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