Diclofenac+serratiopeptidase
About
Diclofenac+serratiopeptidase belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of diclofenac and serratiopeptidase. Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage of the tooth nerve, infection, decay, extraction, or injury.
Diclofenac+serratiopeptidase is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Serratiopeptidase is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.
You can take Diclofenac+serratiopeptidase with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take Diclofenac+serratiopeptidase based on your medical condition. Diclofenac+serratiopeptidase may have common side effects like stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Most of these side effects of Diclofenac+serratiopeptidase do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Try not to stop taking this medicine of your own. Do not take Diclofenac+serratiopeptidase if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. Diclofenac+serratiopeptidase may be associated with a small increased risk of heart attack ‘myocardial infarction. It is advisable not to exceed the recommended dose or duration of treatment.
Uses of Diclofenac+serratiopeptidase
Medicinal Benefits
Diclofenac+serratiopeptidase plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers which cause pain and fever. Diclofenac+serratiopeptidase relieves pain and inflammation in arthritic conditions with the benefit of increased antibiotic penetration and micro-circulation at the injury site. Serratiopeptidase present in Diclofenac+serratiopeptidase is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.
Directions for Use
Storage
Side Effects of Diclofenac+serratiopeptidase
- Stomach ache
- Diarrhoea
- Nausea (feeling sick)
- Indigestion
In-Depth Precautions and Warning
Drug Warnings
Consumption of alcohol should be avoided during the treatment with Diclofenac+serratiopeptidase as it may lead to an increase in the risk of liver damage. Patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, and hypertension (high blood pressure), should not take Diclofenac+serratiopeptidase. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to pain killers and, complications like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Diclofenac+serratiopeptidase. Do not drive or operate heavy machinery as intake of Diclofenac+serratiopeptidase may cause dizziness. Patients who had recently undergone heart bypass surgery should take Diclofenac+serratiopeptidase with caution and only under medical supervision. Use of Diclofenac+serratiopeptidase is contraindicated in kidney failure patients or who are undergoing dialysis.
Drug Interactions
Drug-Drug Interaction: Drugs containing pain killers (nimesulide, oxyphenbutazone, metamizole), anti-cancer (methotrexate), lithium, iodine, and blood clotting agents (warfarin) should not be taken with Diclofenac+serratiopeptidase as they can worsen your condition.
Drug-Food Interaction: Drinking alcohol should be avoided while taking Diclofenac+serratiopeptidase as it can cause unpleasant effects.
Drug-Disease Interaction: People with peptic ulcer, gastric bleeding, severe heart failure, stroke, ulcerative colitis, Crohn's disease, alcoholism, and high blood pressure should avoid intake of Diclofenac+serratiopeptidase. Please seek medical advice.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionYou are recommended not to consume alcohol along with Diclofenac+serratiopeptidase to avoid unpleasant side-effects.
Pregnancy
cautionPlease inform your doctor if you are pregnant or planning to become pregnant before taking Diclofenac+serratiopeptidase.
Breast Feeding
cautionDiclofenac+serratiopeptidase may pass into the breast milk. Consult your doctor for more information on this if you are a breastfeeding mother.
Driving
cautionDiclofenac+serratiopeptidase may affect driving as it causes dizziness. Drive or operate machinery only when you are alert.
Liver
cautionDiclofenac+serratiopeptidase to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.
Kidney
cautionDiclofenac+serratiopeptidase to be taken with caution if you have a history of kidney diseases/conditions. Dose may have to be adjusted by your doctor.
Children
cautionDiclofenac+serratiopeptidase is not recommended for children under 10 years of age. For them dose has to be adjusted and recommended by a child specialist only.
Habit Forming
Diet & Lifestyle Advise
- Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
- Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead you can do stretching, low impact aerobic exercise like walking on treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.
- In chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize level of chemical called cytokines, which ramp up inflammation.
- Your sitting posture is important especially when have pain and inflammation conditions. Try to sit little as possible, and only for short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a foot rest if required.
Patients Concern
Disease/Condition Glossary
Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains, or trauma or post-surgery may require a prolonged amount of time to heal. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation are caused due to sprains, strains, trauma or post-surgery. These types of injuries may require a prolonged amount of time to heal.
FAQs
Diclofenac+serratiopeptidase when taken by patients who are allergic to pain-killers can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease, stomach ulcers and high blood pressure.
You should only take Diclofenac+serratiopeptidase if doctor has prescribed you. The maximum recommended dose of Diclofenac+serratiopeptidase is twice daily. Diclofenac+serratiopeptidase can be one in the morning and one in the evening.
Rheutamoid arthritis is an autoimmune disease that causes chronic inflammation and pain of the joints.
Ankylosing spondylitis is a arthritis of the spine which can lead to the fusion of the vertebrae, lead to pain and inflammation in the spine.
Yes, Diclofenac+serratiopeptidase can cause stomach upset. So, it should be preferably taken with food to avoid it.
